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Redefining Outcome Measures

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The Role of Epiglottis in Obstructive Sleep Apnea

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Abstract

Sleep testing is the most important diagnostic tool in respiratory sleep medicine and is unique in measuring an abundance of simultaneously obtained objective measures such as sleep state, airflow, and oxygen saturation. The data collected resulted in the scoring of sleep and associated events. Traditionally, the diagnosis and severity of obstructive sleep apnea (OSA) have been largely quantified by the numeric calculation of the number of apneas and hypopneas per hour of sleep (AHI). However, the AHI is a surrogate marker for disease severity and is not the only metric. In this chapter, we elaborate on various other objective treatment outcomes to consider. We reflect on various factors to take into account when interpreting sleep studies. We discuss various clinical endpoints since one does not only aim to improve respiratory disturbances during sleep. We focus on how to report on the treatment of patients with OSA. For example, how does one define success? How does one take compliance into consideration since the effectiveness of conservative treatment regarding the reduction of AHI depends both on its impact on airway obstruction and compliance. We consider the impact of sleep position and how to take this factor into consideration.

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Authors and Affiliations

  1. Department of Otorhinolaryngology, OLVG, location West, Amsterdam, The Netherlands

    Madeline J. L. Ravesloot

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  1. Madeline J. L. Ravesloot
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Correspondence to Madeline J. L. Ravesloot .

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  1. General Hospital Celje, Celje, Slovenia

    Matej Delakorda

  2. Jan Tooropstraat, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands

    Nico de Vries

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Ravesloot, M.J.L. (2023). Redefining Outcome Measures. In: Delakorda, M., de Vries, N. (eds) The Role of Epiglottis in Obstructive Sleep Apnea. Springer, Cham. https://doi.org/10.1007/978-3-031-34992-8_4

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