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PPPM Innovation in Primary, Secondary and Tertiary Care

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Predictive, Preventive, and Personalised Medicine: From Bench to Bedside

Abstract

Reactive medicine has reached its ethical, economic and technological limits as demonstrated by pandemic spread of acute infections and chronic disorders. European Association for Predictive, Preventive and Personalised Medicine EPMA in cooperation with the European network of physicians (European Medical Association, EMA, Brussels) synergistically promote the paradigm change from reactive medical services to predictive, preventive and personalised medicine (3PM/PPPM) that is a new philosophy in both—bio/medical sciences and daily medical practice going on hand-in-hand from bench to bedside. Scientifically justified and clinically approved PPPM approach aims to benefit primary, secondary and tertiary care. In a long-term way, the accents are anticipated to get shifted towards the cost-effective protection against health-to-disease transition. A holistic approach and technological innovation are considered.

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References

  1. Radanliev P, De Roure D, Walton R, Van Kleek M, Montalvo RM, Santos O, Maddox L, Cannady S (2020) COVID-19 what have we learned? The rise of social machines and connected devices in pandemic management following the concepts of predictive, preventive and personalized medicine. EPMA J 11(3):311–332. https://doi.org/10.1007/s13167-020-00218-x

    Article  PubMed  PubMed Central  Google Scholar 

  2. Richter K, Kellner S, Hillemacher T, Golubnitschaja O (2021) Sleep quality and COVID-19 outcomes: the evidence-based lessons in the framework of predictive, preventive and personalised (3P) medicine. EPMA J 12(2):221–241. https://doi.org/10.1007/s13167-021-00245-2

    Article  PubMed  PubMed Central  Google Scholar 

  3. Skladany L, Koller T, Adamcova Selcanova S, Vnencakova J, Jancekova D, Durajova V, Laffers L, Svac J, Janickova K, Palkovič M, Kohout P, Golubnitschaja O (2021) Challenging management of severe chronic disorders in acute pandemic situation: chronic liver disease under COVID-19 pandemic as the proof-of-principle model to orchestrate the measures in 3PM context. EPMA J 12(1):1–14. https://doi.org/10.1007/s13167-021-00231-8

    Article  PubMed  PubMed Central  Google Scholar 

  4. Kropp M, Golubnitschaja O, Mazurakova A, Koklesova L, Sargheini N, Vo TKS, de Clerck E, Polivka J Jr, Potuznik P, Polivka J, Stetkarova I, Kubatka P (2023) Thumann G diabetic retinopathy as the leading cause of blindness and early predictor of cascading complications-risks and mitigation. EPMA J 14(1):21–42. https://doi.org/10.1007/s13167-023-00314-8

    Article  PubMed  PubMed Central  Google Scholar 

  5. Koklesova L, Samec M, Liskova A, Zhai K, Büsselberg D, Giordano FA, Kubatka P, Golunitschaja O (2021) Mitochondrial impairments in aetiopathology of multifactorial diseases: common origin but individual outcomes in context of 3P medicine. EPMA J 12(1):27–40. https://doi.org/10.1007/s13167-021-00237-2

    Article  PubMed  PubMed Central  Google Scholar 

  6. Mazurakova A, Koklesova L, Samec M, Kudela E, Kajo K, Skuciova V, Csizmár SH, Mestanova V, Pec M, Adamkov M, Al-Ishaq RK, Smejkal K, Giordano FA, Büsselberg D, Biringer K, Golubnitschaja O, Kubatka P (2022) Anti-breast cancer effects of phytochemicals: primary, secondary, and tertiary care. EPMA J 13(2):315–334. https://doi.org/10.1007/s13167-022-00277-2

    Article  PubMed  PubMed Central  Google Scholar 

  7. Ellinger J, Alajati A, Kubatka P, Giordano FA, Ritter M, Costigliola V, Golubnitschaja O (2022) Prostate cancer treatment costs increase more rapidly than for any other cancer-how to reverse the trend? EPMA J 13(1):1–7. https://doi.org/10.1007/s13167-022-00276-3

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Golubnitschaja O, Costigliola V, EPMA (2012) General report & recommendations in predictive, preventive and personalised medicine 2012: white paper of the European Association for predictive, preventive and personalised medicine. EPMA J 3(1):14. https://doi.org/10.1186/1878-5085-3-14

    Article  PubMed  PubMed Central  Google Scholar 

  9. Golubnitschaja O, Baban B, Boniolo G, Wang W, Bubnov R, Kapalla M, Krapfenbauer K, Mozaffari M, Costigliola V (2016) Medicine in the early twenty-first century: paradigm and anticipation—EPMA position paper 2016. EPMA J 7:23. https://doi.org/10.1186/s13167-016-0072-4

    Article  PubMed  PubMed Central  Google Scholar 

  10. Golubnitschaja O (ed) Book series “Advances in predictive, preventive and personalised medicine”. Springer, Dordrecht, Heidelberg, New York, London. https://www.springer.com/series/10051

  11. Wang W, Yan Y, Guo Z, Hou H, Garcia M, Tan X, Anto EO, Mahara G, Zheng Y, Li B, Wang Y, Guo X, Golubnitschaja O (2021) All around suboptimal health. A joint position paper of the suboptimal health study consortium and European Association for predictive, preventive and personalised medicine. EPMA J 12(4):1–31. https://doi.org/10.1007/s13167-021-00253-2

    Article  Google Scholar 

  12. Golubnitschaja O (ed) (2019., ISBN 978-3-030-13549-2 ISBN 978-3-030-13550-8 (eBook)) Flammer Syndrome—From Phenotype to Associated Pathologies, Prediction, Prevention and Personalisation V.11. https://doi.org/10.1007/978-3-030-13550-8

    Book  Google Scholar 

  13. Koklesova L, Mazurakova A, Samec M, Kudela E, Biringer K, Kubatka P, Golubnitschaja O (2022) Mitochondrial health quality control: measurements and interpretation in the framework of predictive, preventive, and personalized medicine. EPMA J 13:177–193. https://doi.org/10.1007/s13167-022-00281-6

    Article  PubMed  PubMed Central  Google Scholar 

  14. Zhan X, Li J, Guo Y, Golubnitschaja O (2021) Mass spectrometry analysis of human tear fluid biomarkers specific for ocular and systemic diseases in the context of 3P medicine. EPMA J 12(4):449–475. https://doi.org/10.1007/s13167-021-00265-y

    Article  PubMed  PubMed Central  Google Scholar 

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Correspondence to Olga Golubnitschaja .

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Golubnitschaja, O., Kapalla, M., Podbielska, H., Costigliola, V. (2023). PPPM Innovation in Primary, Secondary and Tertiary Care. In: Podbielska, H., Kapalla, M. (eds) Predictive, Preventive, and Personalised Medicine: From Bench to Bedside. Advances in Predictive, Preventive and Personalised Medicine, vol 17. Springer, Cham. https://doi.org/10.1007/978-3-031-34884-6_1

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