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Micro-molding and Its Application to Drug Delivery

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Nano- and Microfabrication Techniques in Drug Delivery

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Abstract

Micro-molding techniques are used in many areas including pharmaceutical technology. Injection molding is the cyclic process of polymer processing. Most of them are thermoplastics. The procedure is performed by injecting a molten polymer of a certain viscosity from an injection unit into a tempered mold using heat and pressure. The workpiece hardens in the mold by cooling or by cross-linking. Hot embossing uses pressure. The template is pressed into a heated polymer. In this case, a thermo-softening polymer is placed between molds, heated, and later allowed to cool maintaining constant pressure. Casting is a process where the non-viscous polymer is poured into a tempered mold. The casting takes the shape of the mold cavity and is created in it by evaporating the solvent or dispersant, gelling, chemical reactions, or cross-linking. These techniques can also be applied to prepare solid dosage forms or controlled-release systems such as implants or vaginal rings among others. In this way, using these techniques results in precise medication. It is directly related to the patient’s quality of life and successful treatment.

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  1. Faculty of Pharmacy, Department of Pharmaceutical Technology, University of Sarajevo, Sarajevo, Bosnia and Herzegovina

    Edina Vranić

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  1. School of Pharmacy, Queen’s University Belfast, Belfast, UK

    Dimitrios Lamprou

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Vranić, E. (2023). Micro-molding and Its Application to Drug Delivery. In: Lamprou, D. (eds) Nano- and Microfabrication Techniques in Drug Delivery . Advanced Clinical Pharmacy - Research, Development and Practical Applications, vol 2. Springer, Cham. https://doi.org/10.1007/978-3-031-26908-0_11

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