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Head and Neck Pathology

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ENT Board Prep

Abstract

Overview of common head and neck pathology. Papillary thyroid carcinoma features the formation of papillae and unique nuclear features like “orphan Annie eye” nuclei and psammoma bodies. Melanoma is characterized by melanin pigment and is S100+, HMB 45+, Melan A+ (melanocytic antigen), Tyrosinase+. Laryngeal papillomas show papillary fronds or finger-like projections of stratified squamous epithelium with fibrovascular cores.

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Further Reading

  1. Balakumar R, Farr MRB, Fernando M, et al. Adult-type rhabdomyoma of the larynx in Birt-Hogg-Dubé syndrome: evidence for a real association. Head Neck Pathol. 2019;13(3):507–11.

    Article  PubMed  Google Scholar 

  2. Benedict JJ, Derkay CS. Recurrent respiratory papillomatosis: a 2020 perspective. Laryngosc Investig Otolaryngol. 2021;6(2):340–5.

    Article  Google Scholar 

  3. Bradford CR, Ferlito A, Devaney KO, et al. Prognostic factors in laryngeal squamous cell carcinoma. Laryngosc Investig Otolaryngol. 2020;5(1):74–81.

    Article  Google Scholar 

  4. Rindi G, Klimstra DS, Abedi-Ardekani B, et al. A common classification framework for neuroendocrine neoplasms: an International Agency for Research on Cancer (IARC) and World Health Organization (WHO) expert consensus proposal. Mod Pathol. 2018;31(12):1770–86.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Griffith CC, Schmitt AC, Little JL, Magliocca KR. New developments in salivary gland pathology: clinically useful ancillary testing and new potentially targetable molecular alterations. Arch Pathol Lab Med. 2017;141(3):381–95.

    Article  PubMed  Google Scholar 

  6. Grayson JW, Hopkins C, Mori E, Senior B, Harvey RJ. Contemporary classification of chronic rhinosinusitis beyond polyps vs no polyps: a review. JAMA Otolaryngol Head Neck Surg. 2020;146(9):831–8.

    Article  PubMed  Google Scholar 

  7. Minni A, Gera R, Bulgheroni C, et al. Endoscopic resection of sinonasal inverted papilloma: a multivariate retrospective analysis of factors affecting recurrence and persistence. Ear Nose Throat J. 2019;100(5):542–8.

    Google Scholar 

  8. Lilja M, Viitasalo S, Hytönen M, et al. Sinonasal oncocytic papilloma-a series of 20 cases with special emphasis on recurrences. Laryngosc Investig Otolaryngol. 2019;4(6):567–72.

    Article  Google Scholar 

  9. Bracigliano A, et al. Sinonasal tumors: update on histological and clinical management. Curr Oncol. 2021;28(4):2420–38.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Rooper LM, Agaimy A, Dickson BC, et al. DEK-AFF2 carcinoma of the sinonasal region and skull base: detailed clinicopathologic characterization of a distinctive entity. Am J Surg Pathol. 2021;45(12):1682–93.

    Article  PubMed  Google Scholar 

  11. Castle JT. Cholesteatoma pearls: practical points and update. Head Neck Pathol. 2018;12(3):419–29.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Asa SL, et al. Middle ear “adenoma”: a neuroendocrine tumor with predominant L cell differentiation. Endocr Pathol. 2021;32(4):433–41.

    Article  CAS  PubMed  Google Scholar 

  13. Majewska A, Budny B, Ziemnicka K, Ruchała M, Wierzbicka M. Head and neck paragangliomas-a genetic overview. Int J Mol Sci. 2020;21(20):7669.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Thompson LDR, Magliocca KR, et al. CAIX and pax-8 commonly immunoreactive in endolymphatic sac tumors: a clinicopathologic study of 26 cases with differential considerations for metastatic renal cell carcinoma in von Hippel-Lindau patients. Head Neck Pathol. 2019;13(3):355–63.

    Article  PubMed  Google Scholar 

  15. Bai Y, Kakudo K, Jung CK. Updates in the pathologic classification of thyroid neoplasms: a review of the World Health Organization classification. Endocrinol Metab. 2020;35(4):696–715.

    Article  Google Scholar 

  16. Juhlin C, Erickson LA. Genomics and epigenomics in parathyroid neoplasia: from bench to surgical pathology practice. Endocr Pathol. 2021;32(1):17–34.

    Article  PubMed  Google Scholar 

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Fan, C.J., Filimonov, A., Olarte, L.S., Magliocca, K., Lin, F.Y. (2023). Head and Neck Pathology. In: Lin, F.Y., Patel, Z.M. (eds) ENT Board Prep. Springer, Cham. https://doi.org/10.1007/978-3-031-26048-3_12

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  • DOI: https://doi.org/10.1007/978-3-031-26048-3_12

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-26047-6

  • Online ISBN: 978-3-031-26048-3

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