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Sweet Syndrome

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European Handbook of Dermatological Treatments

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Abstract

Sweet syndrome (SS) or acute febrile neutrophilic dermatosis is an inflammatory skin disease characterized by fever, peripheral blood neutrophilia, painful tender erythematous plaques on face, neck, and extremities, and histologically by a dense infiltrate of mature neutrophils of the upper dermis. SS can occur in four different subtypes, that is, idiopathic, drug-induced (DISS), paraneoplastic or malignancy-associated (MASS), and drug-induced in a setting of malignancy SS (DISS/MASS). An important hallmark of the disease is its prompt response to systemic corticosteroid therapy.

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Abbreviations

AML:

Acute myeloid leukemia

CML:

Chronic myeloid leukemia

DISS:

Drug-induced sweet syndrome

ESR:

Erythrocyte sedimentation rate

G-CSF:

Granulocyte colony-stimulating factor

GM-CSF:

Granulocyte/macrophage colony-stimulating factor

IFN:

Interferon

IL:

Interleukin

MASS:

Malignancy-associated sweet syndrome

SS:

Sweet syndrome

Th:

Helper T cells

TNF:

Tumor necrosis factor

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Authors and Affiliations

  1. Municipal Hospital Dresden, Academic Teaching Hospital of the Technical University of Dresden, Dresden, Germany

    Uwe Wollina

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  1. Uwe Wollina
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Correspondence to Uwe Wollina .

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Editors and Affiliations

  1. Andreas Syggros Hospital, Athens State University, Athens, Greece

    Andreas D. Katsambas

  2. Research Center CSRMR, Marconi University, Rome, Roma, Italy

    Torello M. Lotti

  3. Andreas Syggros Hospital, Athens State University, Athens, Greece

    Clio Dessinioti

  4. Dermatoloy Unit, Livorno Hospital, Livorno, Italy

    Angelo Massimiliano D'Erme

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Wollina, U. (2023). Sweet Syndrome. In: Katsambas, A.D., Lotti, T.M., Dessinioti, C., D'Erme, A.M. (eds) European Handbook of Dermatological Treatments. Springer, Cham. https://doi.org/10.1007/978-3-031-15130-9_92

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  • DOI: https://doi.org/10.1007/978-3-031-15130-9_92

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  • Publisher Name: Springer, Cham

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  • Online ISBN: 978-3-031-15130-9

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