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Cardiac PET/MR Basics

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FDG-PET/CT and PET/MR in Cardiovascular Diseases

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Abstract

The past decade has seen the emergence of hybrid PET/MR scanners in the pre-clinical and clinical environments, offering new imaging opportunities in various areas of application and organ systems. Well-established in the research setting, PET/MR is now entering the realm of clinical applications, with the potential to provide unique insights into numerous diseases and biological processes. The hybridization of PET and MRI as a simultaneous imaging modality came with challenges and opportunities, ranging from the development of new instrumentation to novel approaches for image acquisition and quantification. For instance, PET/MR required a complete redesign of PET scintillation detectors and front-end electronics to permit operation within the MR environment. New approaches to attenuation correction were needed for PET/MR since MRI does not directly provide information on tissue attenuation properties. PET/MR also offers the opportunity to develop novel algorithms for PET motion correction, leveraging the unique ability of MRI to measure organ motion with high spatiotemporal resolution. This article provides a summary of the challenges and opportunities associated with PET/MR technology, with a particular focus placed on cardiac applications.

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Authors and Affiliations

  1. Gordon Center for Medical Imaging, Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA

    Yoann Petibon, Chao Ma, Jinsong Ouyang & Georges El Fakhri

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  1. Yoann Petibon
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  2. Chao Ma
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  3. Jinsong Ouyang
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  4. Georges El Fakhri
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Correspondence to Georges El Fakhri .

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  1. Montreal Heart Institute, Montréal, QC, Canada

    Matthieu Pelletier-Galarneau

  2. BC Cancer Agency, Vancouver, BC, Canada

    Patrick Martineau

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Petibon, Y., Ma, C., Ouyang, J., El Fakhri, G. (2022). Cardiac PET/MR Basics. In: Pelletier-Galarneau, M., Martineau, P. (eds) FDG-PET/CT and PET/MR in Cardiovascular Diseases. Springer, Cham. https://doi.org/10.1007/978-3-031-09807-9_2

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