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Surgical Management: Management of Traumatic Bone Defects

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Textbook of Polytrauma Management

Abstract

Traumatic bone defects represent a complex clinical scenario and a major cause of patient disability. Advances in fixation methods, bone reconstruction, soft tissue management, and antibiotics have led to an increase in limb salvage rates. Autogenous bone grafting remains the gold standard for small defects, while distraction osteogenesis, vascularized bone grafts and the induced membrane technique among others, offer solutions for the larger defects. Each method carries unique advantages and shortcomings.

These debilitating injuries must be managed in specialized units with input from a multidisciplinary team.

The rehabilitation may be prolonged, while the end result may be associated with a degree of residual functional impairment.

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References

  1. Keating JF, Simpson AHRW, Robinson CM. The management of fractures with bone loss. J Bone Joint Surg Series B. 2005;87:142.

    Article  CAS  Google Scholar 

  2. Trauma A, Support L. Atls 2018. Atls. 2018.

    Google Scholar 

  3. Roberts CS, Pape HC, Jones AL, Malkani AL, Rodriguez JL, Giannoudis PV. Damage control orthopaedics: evolving concepts in the treatment of patients who have sustained orthopaedic trauma. Instr Course Lect. 2005;54:447.

    PubMed  Google Scholar 

  4. Lange RH. Limb reconstruction versus amputation decision making in massive lower extremity trauma. Clin Orthop Relat Res. 1989;243:92.

    Google Scholar 

  5. Mommsen P, Zeckey C, Hildebrand F, Frink M, Khaladj N, Lange N, et al. Traumatic extremity arterial injury in children: epidemiology, diagnostics, treatment and prognostic value of mangled extremity severity score. J Orthop Surg Res. 2010;5:25.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Court-Brown CM, Heckman JD, McQueen MM, Ricci WM, Tornetta P, McKee MD. Rockwood and Green’s fractures in adults. 2015.

    Google Scholar 

  7. Bosse MJ, MacKenzie EJ, Kellam JF, Burgess AR, Webb LX, Swiontkowski MF, et al. A prospective evaluation of the clinical utility of the lower-extremity injury-severity scores. J Bone Joint Surg Ser A. 2001;83:3.

    Article  CAS  Google Scholar 

  8. McNamara MG, Heckman JD, Corley FG. Severe open fractures of the lower extremity: a retrospective evaluation of the mangled extremity severity score (mess). J Orthop Trauma. 1994;8:81.

    Article  CAS  PubMed  Google Scholar 

  9. Pape H-C, Sanders R, Borrelli J, GmbH S-V. The poly-traumatized patient with fractures a multi-disciplinary approach. 2016.

    Google Scholar 

  10. Adams K, Couch L, Cierny G, Calhoun J, Mader JT. In vitro and in vivo evaluation of antibiotic diffusion from antibiotic- impregnated polymethylmethacrylate beads. Clin Orthop Relat Res. 1992;278:244.

    Article  Google Scholar 

  11. Levin LS, Condit DP. Combined injuries—soft tissue management. Clin Orthop Relat Res. 1996;327:172.

    Article  Google Scholar 

  12. Janis JE, Kwon RK, Attinger CE. The new reconstructive ladder: modifications to the traditional model. Plast Reconstr Surg. 2011;127:2055.

    Article  Google Scholar 

  13. Mauffrey C, Barlow BT, Smith W. Management of segmental bone defects. J Am Acad Orthop Surg. 2015;23:143.

    PubMed  Google Scholar 

  14. Nauth A, Schemitsch E, Norris B, Nollin Z, Watson JT. Critical-size bone defects. J Orthop Trauma [Internet]. 2018;32:S7–11. http://journals.lww.com/00005131-201803003-00002

    Article  Google Scholar 

  15. Roddy E, DeBaun MR, Daoud-Gray A, Yang YP, Gardner MJ. Treatment of critical-sized bone defects: clinical and tissue engineering perspectives. Eur J Orthop Surg Traumatol. 2018;28:351.

    Article  PubMed  Google Scholar 

  16. Obremskey W, Molina C, Collinge C, Nana A, Tornetta P, Sagi C, et al. Current practice in the management of open fractures among orthopaedic trauma surgeons. Part A: initial management. A survey of orthopaedic trauma surgeons. J Orthop Trauma. 2014;28:e198.

    Article  PubMed  Google Scholar 

  17. Lasanianos NG, Kanakaris NK, Giannoudis PV. Current management of long bone large segmental defects. Orthop Trauma. 2010;24:149.

    Article  Google Scholar 

  18. Hinsche AF, Giannoudis PV, Matthews SE, Smith RM. Spontaneous healing of large femoral cortical bone defects: does genetic predisposition play a role? Acta Orthop Belg. 2003;69:441.

    PubMed  Google Scholar 

  19. Bauer TW, Muschler GF. Bone graft materials: an overview of the basic science. Clin Orthop Relat Res. 2000;371:10.

    Article  Google Scholar 

  20. Dimitriou R, Mataliotakis GI, Angoules AG, Kanakaris NK, Giannoudis PV. Complications following autologous bone graft harvesting from the iliac crest and using the RIA: a systematic review. Injury. 2011;42:S3-15.

    Article  PubMed  Google Scholar 

  21. Pfeifer R, Kobbe P, Knobe M, Pape H-C. The reamer-irrigator-aspirator (RIA) system. Oper Orthop Traumatol. 2011;23(5):446–52.

    Article  CAS  PubMed  Google Scholar 

  22. Cox G, Jones E, McGonagle D, Giannoudis PV. Reamer-irrigator-aspirator indications and clinical results: a systematic review. Int Orthop. 2011;35:951.

    Article  PubMed  PubMed Central  Google Scholar 

  23. Ilizarov GA. The tension-stress effect on the genesis and growth of tissues. Part I. The influence of stability of fixation and soft-tissue preservation. Clin Orthop Relat Res. 1989;238:249.

    Article  Google Scholar 

  24. Aronson J, Johnson E, Harp JH. Local bone transportation for treatment of intercalary defects by the Ilizarov technique: biomechanical and clincial considerations. Clin Orthop Relat Res. 1989;243:71.

    Article  Google Scholar 

  25. Wozasek GE, Zak L. Acute shortening and then lengthening. In: Rozbruch SR, Hamdy R, editors. Limb lengthening and reconstruction surgery case atlas [internet]. Cham: Springer International Publishing; 2015. p. 1–9. https://doi.org/10.1007/978-3-319-02767-8_153-1.

    Chapter  Google Scholar 

  26. Papakostidis C, Bhandari M, Giannoudis PV. Distraction osteogenesis in the treatment of long bone defects of the lower limbs: effectiveness, complications and clinical results; a systematic review and meta-analysis. Bone and Joint Journal. 2013;95-B:1973.

    Article  Google Scholar 

  27. Lin CH, Wei FC, Chen HC, Chuang DCC. Outcome comparison in traumatic lower-extremity reconstruction by using various composite vascularized bone transplantation. Plast Reconstr Surg. 1999;104:984.

    Article  CAS  PubMed  Google Scholar 

  28. Shin EH, Shin AY. Vascularized bone grafts in orthopaedic surgery. JBJS Rev. 2017;5:e1.

    Article  PubMed  Google Scholar 

  29. Gonzalez del Pino J, Gomez Castresana F, Benito M, Weilan DAJ. Role of free vascularized bone grafts in the experimentally-induced ischemic necrosis of the femoral head. J Reconstr Microsurg. 1990;6:151.

    Article  CAS  PubMed  Google Scholar 

  30. Friedrich JB, Moran SL, Bishop AT, Wood CM, Shin AY. Free vascularized fibular graft salvage of complications of long-bone allograft after tumor reconstruction. J Bone Joint Surg Ser A. 2008;90:93.

    Article  Google Scholar 

  31. Friedrich JB, Moran SL, Bishop AT, Wood CM, Shin AY. Vascularized fibula flap onlay for salvage of pathologic fracture of the long bones. Plast Reconstr Surg. 2008;121:2001.

    Article  CAS  PubMed  Google Scholar 

  32. Khira YM, Badawy HA. Pedicled vascularized fibular graft with Ilizarov external fixator for reconstructing a large bone defect of the tibia after tumor resection. J Orthop Traumatol. 2013;14:91.

    Article  PubMed  PubMed Central  Google Scholar 

  33. Allsopp BJ, Hunter-Smith DJ, Rozen WM. Vascularized versus nonvascularized bone grafts: what is the evidence? Clin Orthop Relat Res. 2016;474:1319.

    Article  PubMed  PubMed Central  Google Scholar 

  34. Cavadas PC, Landín L, Ibáñez J, Nthumba P. Reconstruction of major traumatic segmental bone defects of the tibia with vascularized bone transfers. Plast Reconstr Surg. 2010;125:215.

    Article  CAS  PubMed  Google Scholar 

  35. Zhen P, Hu YY, Luo ZJ, Liu XY, Lu H, Li XS. One-stage treatment and reconstruction of gustilo type III open tibial shaft fractures with a vascularized fibular osteoseptocutaneous flap graft. J Orthop Trauma. 2010;24:745.

    Article  PubMed  Google Scholar 

  36. Masquelet AC, Fitoussi F, Begue T, Muller GP. Reconstruction of the long bones by the induced membrane and spongy autograft. Ann Chir Plast Esthet. 2000;45:346.

    CAS  PubMed  Google Scholar 

  37. Masquelet A, Kanakaris NK, Obert L, Stafford P, Giannoudis PV. Bone repair using the Masquelet technique. J Bone Joint Surg (Am Vol). 2019;101:1024.

    Article  Google Scholar 

  38. Taylor BC, French BG, Ty Fowler T, Russell J, Poka A. Induced membrane technique for reconstruction to manage bone loss. J Am Acad Orthop Surg. 2012;20:142.

    Article  PubMed  Google Scholar 

  39. Morelli I, Drago L, George DA, Gallazzi E, Scarponi S, Romanò CL. Masquelet technique: myth or reality? A systematic review and meta-analysis. Injury [Internet]. 2016;47:S68–76. https://linkinghub.elsevier.com/retrieve/pii/S0020138316308427

    Article  Google Scholar 

  40. Karger C, Kishi T, Schneider L, Fitoussi F, Masquelet AC. Treatment of posttraumatic bone defects by the induced membrane technique. Orthop Traumatol Surg Res. 2012;98:97.

    Article  CAS  PubMed  Google Scholar 

  41. Cobos JA, Lindsey RW, Gugala Z. The cylindrical titanium mesh cage for treatment of a long bone segmental defect: description of a new technique and report of two cases. J Orthop Trauma. 2000;14:54.

    Article  CAS  PubMed  Google Scholar 

  42. Lindsey RW, Gugala Z. Cylindrical titanium mesh cage for the reconstruction of long bone defects. Osteosynthesis Trauma Care. 2004;12(03):108–15.

    Article  Google Scholar 

  43. Gugala Z, Lindsey RW, Gogolewski S. New approaches in the treatment of critical-size segmental defects in long bones. Macromol Symp [Internet]. 2007;253(1):147–61. https://doi.org/10.1002/masy.200750722.

    Article  CAS  Google Scholar 

  44. Sheth NP, Bonadio MB, Demange MK. Bone loss in revision total knee arthroplasty: evaluation and management. J Am Acad Orthop Surg. 2017;25:348.

    Article  PubMed  Google Scholar 

  45. Kamath AF, Lewallen DG, Hanssen AD. Porous tantalum metaphyseal cones for severe tibial bone loss in revision knee arthroplasty: a five to nine-year follow-up. J Bone Joint Surg Am. 2015;97:216.

    Article  PubMed  Google Scholar 

  46. Panegrossi G, Ceretti M, Papalia M, Casella F, Favetti F, Falez F. Bone loss management in total knee revision surgery. Int Orthop. 2014;38:419.

    Article  PubMed  PubMed Central  Google Scholar 

  47. Gautam D, Malhotra R. Megaprosthesis versus allograft prosthesis composite for massive skeletal defects. J Clin Orthop Trauma. 2018;9:63.

    Article  PubMed  Google Scholar 

  48. De Gori M, Scoccianti G, Frenos F, Bettini L, Familiari F, Gasparini G, et al. Modular endoprostheses for nonneoplastic conditions: midterm complications and survival. Biomed Res Int. 2016;2016:2606521.

    PubMed  PubMed Central  Google Scholar 

  49. Capanna R, Scoccianti G, Frenos F, Vilardi A, Beltrami G, Campanacci DA. What was the survival of Megaprostheses in lower limb reconstructions after tumor resections? Clin Orthop Relat Res. 2015;473:820.

    Article  PubMed  Google Scholar 

  50. Calori GM, Colombo M, Ripamonti C, Malagoli E, Mazza E, Fadigati P, et al. Megaprosthesis in large bone defects: opportunity or chimaera? Injury. 2014;45(2):388–93.

    Article  CAS  PubMed  Google Scholar 

  51. Calori GM, Albisetti W, Agus A, Iori S, Tagliabue L. Risk factors contributing to fracture non-unions. Injury. 2007;38:S11.

    Article  PubMed  Google Scholar 

  52. Calori GM, Phillips M, Jeetle S, Tagliabue L, Giannoudis PV. Classification of non-union: need for a new scoring system? Injury. 2008;39(Suppl.2):S59–63.

    PubMed  Google Scholar 

  53. Calori GM, Colombo M, Malagoli E, Mazzola S, Bucci M, Mazza E. Megaprosthesis in post-traumatic and periprosthetic large bone defects: issues to consider. Injury. 2014;45:S105.

    Article  PubMed  Google Scholar 

  54. Korim MT, Esler CNA, Ashford RU. Systematic review of proximal femoral arthroplasty for non-neoplastic conditions. J Arthroplast. 2014;29:2117.

    Article  Google Scholar 

  55. Korim MT, Esler CNA, Reddy VRM, Ashford RU. A systematic review of endoprosthetic replacement for non-tumour indications around the knee joint. Knee. 2013;20:367.

    Article  PubMed  Google Scholar 

  56. Vaishya R, Thapa SS, Vaish A. Non-neoplastic indications and outcomes of the proximal and distal femur megaprosthesis: a critical review. Knee Surg Relat Res. 2020;32:18.

    Article  PubMed  PubMed Central  Google Scholar 

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Correspondence to Peter V. Giannoudis .

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Patsiogiannis, N., Giannoudis, P.V. (2022). Surgical Management: Management of Traumatic Bone Defects. In: Pape, HC., Borrelli Jr., J., Moore, E.E., Pfeifer, R., Stahel, P.F. (eds) Textbook of Polytrauma Management . Springer, Cham. https://doi.org/10.1007/978-3-030-95906-7_31

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  • DOI: https://doi.org/10.1007/978-3-030-95906-7_31

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