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Adipose Tissue Lipid Metabolism During Exercise

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Exercise Metabolism

Part of the book series: Physiology in Health and Disease ((PIHD))

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Abstract

Adipose tissue-derived fatty acids are the primary source of energy during low-intensity exercise. Although the relative contribution of fat to energy production during exercise decreases with increasing exercise intensity, fatty acids still contribute meaningfully to energy production even during vigorous exercise. How exercise triggers the liberation of fatty acids from this “remote” energy storage site for subsequent oxidation in the exercising muscle is complex, with multiple integrated steps and some seemingly paradoxical regulation. Adipose tissue metabolic function and composition differ considerably in subcutaneous vs. visceral adipose tissue beds, and there are also sizable differences between subcutaneous adipose tissue in different regions of the human body (e.g., subcutaneous abdominal vs. subcutaneous femoral/gluteal), whereas most of the fatty acids used for energy during exercise are derived from triacylglycerol stored in subcutaneous abdominal white adipose tissue. This chapter will focus primarily on changes in subcutaneous white adipose tissue that occur during and right after a session of endurance exercise.

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  1. Substrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, MI, USA

    Jeffrey F. Horowitz

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    Glenn McConell

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Horowitz, J.F. (2022). Adipose Tissue Lipid Metabolism During Exercise. In: McConell, G. (eds) Exercise Metabolism. Physiology in Health and Disease. Springer, Cham. https://doi.org/10.1007/978-3-030-94305-9_7

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