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Procalcitonin-Guided Antibiotic Discontinuation

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Reducing Mortality in Critically Ill Patients

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Abstract

Procalcitonin (PCT) is a blood biomarker used in clinical practice to detect bacterial etiology in patients with sepsis or acute respiratory tract infection, to assess infection severity, and to monitor the effectiveness of antibiotic therapy. In February 2017, the U.S. Food and Drug Administration (FDA) approved the use of the first PCT assay to guide antibiotic use in the context of lower respiratory tract infections (LRTI) and sepsis [1].

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Authors and Affiliations

  1. Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy

    Marta Mucchetti, Nicolò Maimeri & Pasquale Nardelli

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  1. Marta Mucchetti
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  2. Nicolò Maimeri
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  3. Pasquale Nardelli
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Correspondence to Marta Mucchetti .

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Editors and Affiliations

  1. Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy

    Giovanni Landoni

  2. Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy

    Martina Baiardo Redaelli

  3. Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy

    Chiara Sartini

  4. Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy

    Alberto Zangrillo

  5. Department of Intensive Care, Austin Hospital, Heidelberg, VIC, Australia

    Rinaldo Bellomo

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Mucchetti, M., Maimeri, N., Nardelli, P. (2021). Procalcitonin-Guided Antibiotic Discontinuation. In: Landoni, G., Baiardo Redaelli, M., Sartini, C., Zangrillo, A., Bellomo, R. (eds) Reducing Mortality in Critically Ill Patients. Springer, Cham. https://doi.org/10.1007/978-3-030-71917-3_15

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  • DOI: https://doi.org/10.1007/978-3-030-71917-3_15

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