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Curcumin and Piperine in COVID-19: A Promising Duo to the Rescue?

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Identification of Biomarkers, New Treatments, and Vaccines for COVID-19

Part of the book series: Advances in Experimental Medicine and Biology ((PMISB,volume 1327))

Abstract

COVID-19 is now pandemic throughout the world, and scientists are searching for effective therapies to prevent or treat the disease. The combination of curcumin and piperine is a potential option for the management of COVID-19 based on several mechanisms including antiviral, anti-inflammatory, immunomodulatory, antifibrotic, and antioxidant effects. Here, we describe the probable mechanism of curcumin-piperine against COVID-19. Administration of curcumin-piperine combination appears as a potential strategy to counterbalance the pathophysiological features of COVID-19 including inflammation. The optimal dose and duration of curcumin-piperine supplementation should be determined in the future.

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Acknowledgements

The authors would like to thank the Department of Community Nutrition of Isfahan University of Medical Sciences.

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Authors and Affiliations

  1. Student Research Committee, Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran

    Mahsa Miryan

  2. Nutrition Research Center, Student Research Committee, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran

    Mahsa Miryan

  3. Nutritional Sciences Department, School of Nutritional Sciences and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran

    Davood Soleimani

  4. Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

    Gholamreza Askari & Mohammad Bagherniya

  5. Anesthesia and Critical Care Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

    Gholamreza Askari & Mohammad Bagherniya

  6. Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran

    Gholamreza Askari & Mohammad Bagherniya

  7. Department of Food Science and Technology, Quchan Branch, Islamic Azad University, Quchan, Iran

    Tannaz Jamialahmadi

  8. Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

    Tannaz Jamialahmadi

  9. Laboratory of Neuroproteomics, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil

    Paul C. Guest

  10. Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran

    Amirhossein Sahebkar

  11. Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

    Amirhossein Sahebkar

  12. Polish Mother’s Memorial Hospital Research Institute (PMMHRI), Lodz, Poland

    Amirhossein Sahebkar

  13. School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

    Amirhossein Sahebkar

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  1. Mahsa Miryan
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  2. Davood Soleimani
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  3. Gholamreza Askari
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  4. Tannaz Jamialahmadi
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  5. Paul C. Guest
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  6. Mohammad Bagherniya
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  7. Amirhossein Sahebkar
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Corresponding authors

Correspondence to Mohammad Bagherniya or Amirhossein Sahebkar .

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  1. Charlesworth House, Debden, Essex, UK

    Paul C. Guest

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Miryan, M. et al. (2021). Curcumin and Piperine in COVID-19: A Promising Duo to the Rescue?. In: Guest, P.C. (eds) Identification of Biomarkers, New Treatments, and Vaccines for COVID-19. Advances in Experimental Medicine and Biology(), vol 1327. Springer, Cham. https://doi.org/10.1007/978-3-030-71697-4_16

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