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From Substitution to Regeneration: The Tridimensional Interplay Between Cells and Biomaterials

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Women in 3D Printing

Part of the book series: Women in Engineering and Science ((WES))

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Abstract

Advancements in technology allow for longer lifespan, creating the need for improved medical devices, especially in orthopedics. Using technologies like additive manufacturing (AM), it is possible to achieve a high degree of personalization, namely patient-specific implants with complex shapes and controlled porous structures. This process not only foments the creativity, but it also promotes the research of new biomaterials, and the optimisation of existing processes and techniques. During my PhD studies, I aimed to exploit AM for the development of novel materials and devices within bone regenerative medicine. I have investigated the use of Apatite-Wollastonite (AW), a bioactive glass-ceramic, as feedstock for AM techniques. From doping of AW powders with alumina to the use of the AW precursor glass as a filler for polymer-ceramic biocomposites, the goal was always to obtain a device able to improve osseointegration. A material like AW can be easily tuned, allowing for a high degree of freedom composition-wise. Two AM techniques were applied, binder jetting and fused filament fabrication, to create a load bearing device and scaffolds for critical-size defects, respectively. The choice of the developed materials and techniques envisioned the fast translation into an industrial context, and their easy commercialization.

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Authors and Affiliations

  1. Politecnico di Torino, Torino, Italy

    Priscila Melo

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  1. Priscila Melo
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Correspondence to Priscila Melo .

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  1. StaceyD Consulting, LLC, Peoria, IL, USA

    Stacey M DelVecchio

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Melo, P. (2021). From Substitution to Regeneration: The Tridimensional Interplay Between Cells and Biomaterials. In: DelVecchio, S.M. (eds) Women in 3D Printing. Women in Engineering and Science. Springer, Cham. https://doi.org/10.1007/978-3-030-70736-1_9

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  • DOI: https://doi.org/10.1007/978-3-030-70736-1_9

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