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Gut Involvement in Cellular Immunodeficiencies

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Cellular Primary Immunodeficiencies

Part of the book series: Rare Diseases of the Immune System ((RDIS))

Abstract

Primary cellular immunodeficiencies may often initially present with manifestations affecting the gastrointestinal tract. Not only infections but also inflammatory, autoimmune, and in some cases malignant manifestations may suggest the presence of a defect in the immune system.

Gastrointestinal manifestations are present in 5–50% of patients with primary immunodeficiency, which is not surprising since the intestine is the largest lymphoid organ.

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Authors and Affiliations

  1. Department of Rheumatology and Clinical Immunology, Medical Center—University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany

    Arianna Troilo & Natalie Frede

  2. Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy

    Arianna Troilo, Chiara Della Bella & Mario Milco D’Elios

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  1. Arianna Troilo
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  2. Natalie Frede
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  3. Chiara Della Bella
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  4. Mario Milco D’Elios
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Correspondence to Mario Milco D’Elios .

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Editors and Affiliations

  1. Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy

    Mario Milco D'Elios

  2. Department of Life Sciences, University of Siena, Siena, Italy

    Cosima Tatiana Baldari

  3. Department of Experimental and Clinical Medicine, University of Florence, Firenze, Florence, Italy

    Francesco Annunziato

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Troilo, A., Frede, N., Della Bella, C., D’Elios, M.M. (2021). Gut Involvement in Cellular Immunodeficiencies. In: D'Elios, M.M., Baldari, C.T., Annunziato, F. (eds) Cellular Primary Immunodeficiencies. Rare Diseases of the Immune System. Springer, Cham. https://doi.org/10.1007/978-3-030-70107-9_13

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