Abstract
We aim to extend existing models of single-cell mechanics to the EMI framework, to define spatially resolved mechanical models of cardiac myocytes embedded in a passive extracellular space. The models introduced here will be pure mechanics models employing fairly simple constitutive laws for active and passive mechanics. Future extensions of the models may include a coupling to the electrophysiology and electro-diffusion models described in the other chapters, to study the impact of spatially heterogeneous ion concentrations on the cell and tissue mechanics.
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Telle, Å., Wall, S.T., Sundnes, J. (2021). Modeling Cardiac Mechanics on a Sub-Cellular Scale. In: Tveito, A., Mardal, KA., Rognes, M.E. (eds) Modeling Excitable Tissue. Simula SpringerBriefs on Computing(), vol 7. Springer, Cham. https://doi.org/10.1007/978-3-030-61157-6_3
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