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Dietary Management by Probiotics, Prebiotics and Synbiotics for the Prevention of Antimicrobial Resistance

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Sustainable Agriculture Reviews 49

Part of the book series: Sustainable Agriculture Reviews ((SARV,volume 49))

Abstract

The increasing global threat of multi drug resistant pathogens is indicating that this is the time to put together our efforts to develop some approaches to turn down the spread of drug resistivity among the microbial world. The best way to reduce the evolution of antimicrobial resistance is to eliminate the heavy burden of antibiotics from our environment. The unfeasibility of elimination of antibiotics from our healthcare system directs us to develop some effective means to reduce their use at the least level. For this, we need to shift from completely antibiotic dependent therapeutic strategy to the multiple prophylactic and therapeutic approaches. Substantial efforts are being invested worldwide to find the sustainable line of defense against the rising pressure of antimicrobial resistance.

In this chapter we investigated the possible role of alternative multiple strategies using biologics such as probiotics, prebiotics, synbiotics and their metabolites in alleviation of the development of drug resistance. These environment and host friendly approaches could reduce the burden of infections by the means of direct or indirect mechanisms such as colonization interference, antimicrobial activity and stimulation of host defense system. Regardless of prompt research and substantial increase in clinical relevance, the approaches are still used as subsidiary or prophylactic strategy only. Advanced efforts are required to establish them as an absolute therapeutic alternative to reduce or replace the use of antibiotics.

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Elshaghabee, F.M.F., Rokana, N. (2021). Dietary Management by Probiotics, Prebiotics and Synbiotics for the Prevention of Antimicrobial Resistance. In: Panwar, H., Sharma, C., Lichtfouse, E. (eds) Sustainable Agriculture Reviews 49. Sustainable Agriculture Reviews, vol 49. Springer, Cham. https://doi.org/10.1007/978-3-030-58259-3_2

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