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Breast

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Pediatric Ultrasound

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Abstract

Ultrasound is the imaging modality of choice in evaluation of the pediatric breast. Ultrasound is noninvasive, readily performed, and does not involve the administration of ionizing radiation. This chapter provides a comprehensive overview of the clinical applications of ultrasound to disorders of the pediatric and adolescent breast. Normal breast development is described, and common developmental disorders, benign and malignant masses are reviewed. Inflammatory abnormalities and lesions related to maternal estrogen hormonal stimulation are discussed along with a brief review of treatment options.

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Abbreviations

CT:

Computed tomography

GCT:

Granular cell tumor

IMLN:

Intramammary lymph node

MR:

Magnetic resonance

PASH:

Pseudoangiomatous stromal hyperplasia

SMR:

Sexual Maturity Rating

References

  1. Gao Y, Saksena MA, Brachtel EF, terMeulen DC, Rafferty EA. How to approach breast lesions in children and adolescents. Eur J Radiol. 2015;84(7):1350–64.

    Article  PubMed  Google Scholar 

  2. Valeur NS, Rahbar H, Chapman T. Ultrasound of pediatric breast masses: what to do with lumps and bumps. Pediatr Radiol. 2015;45(11):1584–99.

    Article  PubMed  Google Scholar 

  3. Greydanus DE, Matytsina L, Gains M. Breast disorders in children and adolescents. Prim Care. 2006;33:455–502.

    Article  PubMed  Google Scholar 

  4. Lee EJ, Chang Y-W, Oh JH, Hwang J, Hong SS, Kim H-J. Breast lesions in children and adolescents: diagnosis and management. Korean J Radiol. 2018;19(5):978–91.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Evans A, Trimboli RM, Athanasiou A, Balleyguier C, Baltzer PA, Bick U, et al. Breast ultrasound: recommendations for information to women and referring physicians by the European Society of Breast Imaging. Insights Imaging. 2018;9(4):449–61.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Raza S, Odulate A, Ong EM, Chikarmane S, Harston CW. Using real-time tissue elastography for breast lesion evaluation: our initial experience. J Ultrasound Med. 2010;29(4):551–63.

    Google Scholar 

  7. Lee SH, Chang JM, Kim WH, Bae MS, Seo M, Koo HR, et al. Added value of shear-wave elastography for evaluation of breast masses detected with screening US imaging. Radiology. 2014;273(1):61–9.

    Article  PubMed  Google Scholar 

  8. Grossl NA. Supernumerary breast tissue: historical perspectives and clinical features. South Med J. 2000;93(1):29–32.

    Article  CAS  PubMed  Google Scholar 

  9. Kaplowitz PB, Oberfield SE. Reexamination of the age limit for defining when puberty is precocious in girls in the United States: implications for evaluation and treatment. Drug and Therapeutics and Executive Committees of the Lawson Wilkins Pediatric Endocrine Society. Pediatrics. 1999;104(4 Pt 1):936–41.

    Article  CAS  PubMed  Google Scholar 

  10. Tanner JM, Davies PS. Clinical longitudinal standards for height and height velocity for north American children. J Pediatr. 1985;107(3):317–29.

    Article  CAS  PubMed  Google Scholar 

  11. Bruserud IS, Roelants M, Oehme NHB, Eide GE, Bjerknes R, Rosendahl K, et al. Ultrasound assessment of pubertal breast development in girls: intra- and interobserver agreement. Pediatr Radiol. 2018;48(11):1576–83.

    Google Scholar 

  12. García CJ, Espinoza A, Dinamarca V, Navarro O, Daneman A, García H, et al. Breast US in children and adolescents. Radiographics. 2000;20(6):1605–12.

    Article  PubMed  Google Scholar 

  13. Lim HS, Kim SJ, Baek JM, Kim JW, Shin SS, Seon HJ, et al. Sonographic findings of accessory breast tissue in axilla and related diseases. J Ultrasound Med. 2017;36(7):1469–78.

    Article  PubMed  Google Scholar 

  14. DeFilippis EM, Arleo EK. The ABCs of accessory breast tissue: basic information every radiologist should know. AJR Am J Roentgenol. 2014;202(5):1157–62.

    Article  PubMed  Google Scholar 

  15. Caouette-Laberge L, Borsuk D. Congenital anomalies of the breast. Semin Plast Surg. 2013;27(1):36–41.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Chung EM, Cube R, Hall GJ, González C, Stocker JT, Glassman LM. From the archives of the AFIP: breast masses in children and adolescents: radiologic-pathologic correlation. Radiographics. 2009;29(3):907–31.

    Article  PubMed  Google Scholar 

  17. Govrin-Yehudain J, Kogan L, Cohen HI, Falik-Zaccai TC. Familial juvenile hypertrophy of the breast. J Adolesc Health. 2004;35(2):151–5.

    Article  PubMed  Google Scholar 

  18. Troccola A, Maruccia M, Dessy LA, Onesti MG. Cortisone-induced gigantomastia during chemotherapy. G Chir. 2011;32(5):​266–9.

    CAS  PubMed  Google Scholar 

  19. Karagüzel G, Bilen S, Karaçal N, Yıldız K, Livaoğlu M. Virginal breast hypertrophy: different presentations of 2 cases and the role of Tamoxifen as an adjuvant therapy. J Pediatr Adolesc Gynecol. 2016;29(5):e71–4.

    Article  PubMed  Google Scholar 

  20. Hoppe IC, Patel PP, Singer-Granick CJ, Granick MS. Virginal mammary hypertrophy: a meta-analysis and treatment algorithm. Plast Reconstr Surg. 2011;127(6):2224–31.

    Article  CAS  PubMed  Google Scholar 

  21. Dancey A, Khan M, Dawson J, Peart F. Gigantomastia – a classification and review of the literature. J Plast Reconstr Aesthet Surg. 2008;61(5):493–502.

    Google Scholar 

  22. Braunstein GD. Gynecomastia. N Engl J Med. 1993;328(7):490–5.

    Article  CAS  PubMed  Google Scholar 

  23. Leung AKC, Leung AAC. Gynecomastia in infants, children, and adolescents. Recent Pat Endocr Metab Immune Drug Discov. 2017;10(2):127–37.

    Article  PubMed  Google Scholar 

  24. Kaneda HJ, Mack J, Kasales CJ, Schetter S. Pediatric and adolescent breast masses: a review of pathophysiology, imaging, diagnosis, and treatment. AJR Am J Roentgenol. 2013;200(2):W204–12.

    Article  PubMed  Google Scholar 

  25. Rong X, Zhu Q, Jia W, Ma T, Wang X, Guo N, et al. Ultrasonographic assessment of male breast diseases. Breast J. 2018;24(4):599–605.

    Article  PubMed  Google Scholar 

  26. Borders H, Mychaliska G, Gebarski KS. Sonographic features of neonatal mastitis and breast abscess. Pediatr Radiol. 2009;39(9):955–8.

    Article  PubMed  Google Scholar 

  27. Coffin CM. The breast. In: Stocker JT, Dehner LP, editors. Pediatric pathology. 2nd ed. Philadelphia. Lippincott Williams & Wilkins; 2002.

    Google Scholar 

  28. Pettinato G, Manivel JC, Kelly DR, Wold LE, Dehner LP. Lesions of the breast in children exclusive of typical fibroadenoma and gynecomastia. A clinicopathologic study of 113 cases. Pathol Annu. 1989;24(Pt 2):296–328.

    PubMed  Google Scholar 

  29. Luo J, Long T, Cai Y, Teng Y, Fan Z, Liang Z, et al. Abscess drainage with or without antibiotics in lactational breast abscess: study protocol for a randomized controlled trial. Infect Drug Resist. 2020;13:183–90.

    Google Scholar 

  30. McHoney M, Munro F, MacKinlay G. Mammary duct ectasia in children: report of a short series and review of the literature. Early Hum Dev. 2011;87(8):527–30.

    Article  PubMed  Google Scholar 

  31. Aydin R, Gul SB, Polat AV. Detection of duct ectasia of mammary gland by ultrasonography in a neonate with bloody nipple discharge. Pediatr Neonatol. 2014;55(3):228–30.

    Article  PubMed  Google Scholar 

  32. Huneeus A, Schilling A, Horvath E, Pinochet M, Carrasco O. Retroareolar cysts in the adolescent. J Pediatr Adolesc Gynecol. 2003;16(1):45–9.

    Article  PubMed  Google Scholar 

  33. Wallace D, Sian A, Carne A, Irvine TE. Diagnosis and management of retroareolar cysts in adolescents: a case report. J Surg Case Rep. 2013;2013(7):rjt052.

    Article  PubMed  PubMed Central  Google Scholar 

  34. Talaei A, Moradi A, Rafiei F. The evaluation of the effect of metformin on breast fibrocystic disease. Breast Dis. 2017;37(2):49–53.

    Article  CAS  PubMed  Google Scholar 

  35. Malherbe K, Fatima S. Fibrocystic breast disease. StatPearls [Internet]. StatPearls publishing: Treasure Island; 2020. [cited 2020 Feb 17]. Available from: http://www.ncbi.nlm.nih.gov/books/NBK551609/

    Google Scholar 

  36. Boyle M, Lakhoo K, Ramani P. Galactocele in a male infant: case report and review of literature. Pediatr Pathol. 1993;13(3):305–8.

    Article  CAS  PubMed  Google Scholar 

  37. Alaniz VI, Jeudy M, Pearlman M, Quint EH. Galactocele in a prepubertal girl. J Pediatr Adolesc Gynecol. 2017;30(4):499–500.

    Google Scholar 

  38. Rajdev SK, Makwana N, Lester R, Agwu JC. An unusual case of bilateral galactocoele in a male infant. Arch Dis Child. 2011;96(11):1087.

    Article  PubMed  Google Scholar 

  39. Welch ST, Babcock DS, Ballard ET. Sonography of pediatric male breast masses: gynecomastia and beyond. Pediatr Radiol. 2004;34(12):952–7.

    Article  PubMed  Google Scholar 

  40. Nguyen C, Kettler MD, Swirsky ME, Miller VI, Scott C, Krause R, et al. Male breast disease: pictorial review with radiologic-pathologic correlation. Radiographics. 2013;33(3):763–79.

    Article  PubMed  Google Scholar 

  41. Tayyab SJ, Adrada BE, Rauch GM, Yang WT. A pictorial review: multimodality imaging of benign and suspicious features of fat necrosis in the breast. Br J Radiol. 2018;91(1092):20180213.

    Article  PubMed  PubMed Central  Google Scholar 

  42. Bilgen IG, Ustun EE, Memis A. Fat necrosis of the breast: clinical, mammographic and sonographic features. Eur J Radiol. 2001;39(2):92–9.

    Article  CAS  PubMed  Google Scholar 

  43. Soo MS, Kornguth PJ, Hertzberg BS. Fat necrosis in the breast: sonographic features. Radiology. 1998;206(1):261–9.

    Article  CAS  PubMed  Google Scholar 

  44. Hudspeth TN, Shin K, Babiera GV, Krishnamurthy S, Woodtichartpreecha P, Karbasian N, et al. A pictorial review of sonography of intramammary lymph nodes: when to care and what to do about it. Ultrasound Q. 2019;35(1):74–8.

    Article  PubMed  Google Scholar 

  45. Rampaul RS, Dale OT, Mitchell M, Blamey RW, Macmillan RD, Robertson JF, et al. Incidence of intramammary nodes in completion mastectomy specimens after axillary node sampling: implications for breast conserving surgery. Breast. 2008;17(2):195–8.

    Google Scholar 

  46. Weinstein SP, Conant EF, Orel SG, Zuckerman JA, Bellah R. Spectrum of US findings in pediatric and adolescent patients with palpable breast masses. Radiographics. 2000;20(6):1613–21.

    Article  CAS  PubMed  Google Scholar 

  47. Paltiel HJ, Burrows PE, Kozakewich HP, Zurakowski D, Mulliken JB. Soft-tissue vascular anomalies: utility of US for diagnosis. Radiology. 2000;214(3):747–54.

    Article  CAS  PubMed  Google Scholar 

  48. Ryu JY, Eo PS, Lee JS, Lee JW, Lee SJ, Lee JM, et al. Surgical approach for venous malformation in the head and neck. Arch Craniofac Surg. 2019;20(5):304–9.

    Article  PubMed  PubMed Central  Google Scholar 

  49. Boon LM, Mulliken JB, Enjolras O, Vikkula M. Glomuvenous malformation (glomangioma) and venous malformation: distinct clinicopathologic and genetic entities. Arch Dermatol. 2004;140(8):971–6.

    Article  PubMed  Google Scholar 

  50. Richter GT, Friedman AB. Hemangiomas and vascular malformations: current theory and management. Int J Pediatr. 2012;2012:​645678.

    Article  PubMed  PubMed Central  Google Scholar 

  51. Berenguer B, Burrows PE, Zurakowski D, Mulliken JB. Sclerotherapy of craniofacial venous malformations: complications and results. Plast Reconstr Surg. 1999;104(1):1–11.

    Google Scholar 

  52. Merrow AC, Gupta A, Patel MN, Adams DM. 2014 revised classification of vascular lesions from the international society for the study of vascular anomalies: radiologic-pathologic update. Radiographics. 2016;36(5):1494–516.

    Article  PubMed  Google Scholar 

  53. Park T, Lee HS, Jung EJ, Kim JY, Jeong CY, Ju YT, et al. Concomitant breast and axillary lymphangioma in an adult: a case report and a review of the literature. Medicine (Baltimore). 2018;97(45):e12946.

    Article  Google Scholar 

  54. Sanchez R, Ladino-Torres MF, Bernat JA, Joe A, DiPietro MA. Breast fibroadenomas in the pediatric population: common and uncommon sonographic findings. Pediatr Radiol. 2010;40(10):​1681–9.

    Article  PubMed  Google Scholar 

  55. Vagios I, Nonni A, Liakea A, Constantinidou A, Kontos M. Intraductal papilloma of the male breast: a case report and review of the literature. J Surg Case Rep. 2019;2019(2):rjz023.

    Article  PubMed  PubMed Central  Google Scholar 

  56. Eiada R, Chong J, Kulkarni S, Goldberg F, Muradali D. Papillary lesions of the breast: MRI, ultrasound, and mammographic appearances. AJR Am J Roentgenol. 2012;198(2):264–71.

    Article  PubMed  Google Scholar 

  57. Lad S, Seely J, Elmaadawi M, Peddle S, Perkins G, Robertson S, et al. Juvenile papillomatosis: a case report and literature review. Clin Breast Cancer. 2014;14(5):e103–5.

    Article  CAS  PubMed  Google Scholar 

  58. Rosen PP, Kimmel M. Juvenile papillomatosis of the breast. A follow-up study of 41 patients having biopsies before 1979. Am J Clin Pathol. 1990;93(5):599–603.

    Article  CAS  PubMed  Google Scholar 

  59. Bazzocchi F, Santini D, Martinelli G, Piccaluga A, Taffurelli M, Grassigli A, et al. Juvenile papillomatosis (epitheliosis) of the breast. A clinical and pathologic study of 13 cases. Am J Clin Pathol. 1986;86(6):745–8.

    Article  CAS  PubMed  Google Scholar 

  60. Yilmaz R, Bayramoglu Z, Bicen F, Kayhan A, Yesil S, Acunas G. Sonographic and magnetic resonance imaging characteristics of juvenile papillomatosis: three cases with different manifestations. Ultrasound Q. 2017;33(2):174–8.

    Article  PubMed  Google Scholar 

  61. Elsedfy H. A clinical approach to benign breast lesions in female adolescents. Acta Biomed. 2017;88(2):214–21.

    PubMed  PubMed Central  Google Scholar 

  62. Virk RK, Khan A. Pseudoangiomatous stromal hyperplasia: an overview. Arch Pathol Lab Med. 2010;134(7):1070–4.

    Article  PubMed  Google Scholar 

  63. Raj SD, Sahani VG, Adrada BE, Scoggins ME, Albarracin CT, Woodtichartpreecha P, et al. Pseudoangiomatous stromal hyperplasia of the breast: multimodality review with pathologic correlation. Curr Probl Diagn Radiol. 2017;46(2):130–5.

    Article  PubMed  Google Scholar 

  64. Mai C, Rombaut B, Hertveldt K, Claikens B, Van Wettere P. Diffuse pseudoangiomatous stromal hyperplasia of the breast: a case report and a review of the radiological characteristics. JBR-BTR. 2014;97(2):81–3.

    CAS  PubMed  Google Scholar 

  65. Wieman SM, Landercasper J, Johnson JM, Ellis RL, Wester SM, Lambert PJ, et al. Tumoral pseudoangiomatous stromal hyperplasia of the breast. Am Surg. 2008;74(12):1211–4.

    Article  PubMed  Google Scholar 

  66. Yoon KH, Koo B, Lee KB, Lee H, Lee J, Kim JY, et al. Optimal treatment of pseudoangiomatous stromal hyperplasia of the breast. Asian J Surg. 2020;43(7):735–41.

    Google Scholar 

  67. Powell CM, Cranor ML, Rosen PP. Pseudoangiomatous stromal hyperplasia (PASH). A mammary stromal tumor with myofibroblastic differentiation. Am J Surg Pathol. 1995;19(3):270–7.

    Article  CAS  PubMed  Google Scholar 

  68. Vuitch MF, Rosen PP, Erlandson RA. Pseudoangiomatous hyperplasia of mammary stroma. Hum Pathol. 1986;17(2):185–91.

    Article  CAS  PubMed  Google Scholar 

  69. Ravikanth R, Kamalasekar K. Imaging of lactating adenoma: differential diagnosis of solid mass lesion in a lactating woman. J Med Ultrasound. 2019;27(4):208–10.

    Article  PubMed  PubMed Central  Google Scholar 

  70. Barco Nebreda I, Vidal MC, Fraile M, Canales L, González C, Giménez N, et al. Lactating adenoma of the breast. J Hum Lact. 2016;32(3):559–62.

    Article  PubMed  Google Scholar 

  71. Sabate JM, Clotet M, Torrubia S, Gomez A, Guerrero R, de las Heras P, et al. Radiologic evaluation of breast disorders related to pregnancy and lactation. Radiographics. 2007;27(Suppl 1):S101–24.

    Article  PubMed  Google Scholar 

  72. Erguvan-Dogan B, Dempsey PJ, Ayyar G, Gilcrease MZ. Primary desmoid tumor (extraabdominal fibromatosis) of the breast. AJR Am J Roentgenol. 2005;185(2):488–9.

    Article  PubMed  Google Scholar 

  73. Rosen PP, Ernsberger D. Mammary fibromatosis. A benign spindle-cell tumor with significant risk for local recurrence. Cancer. 1989;63(7):1363–9.

    Article  CAS  PubMed  Google Scholar 

  74. Grimaldi MC, Trentin C, Lo Gullo R, Cassano E. Fibromatosis of the breast mimicking cancer: a case report. Radiol Case Rep. 2018;13(1):1–5.

    Article  PubMed  Google Scholar 

  75. Muller M, Dessogne P, Baron M, Picquenot JM, Riopel C, Diologent B, et al. Desmoid tumor of the breast in a 9 years old little girl. Ann Pathol. 2011;31(1):41–5.

    Article  PubMed  Google Scholar 

  76. Al-Balas M, De Leo A, Serra M, Santini D, Taffurelli M. Granular cell tumour of the breast: a rare presentation of a breast mass in an elderly female with a subsequent breast cancer diagnosis. SAGE Open Med Case Rep. 2019;7:2050313X19841154.

    Google Scholar 

  77. Adeniran A, Al-Ahmadie H, Mahoney MC, Robinson-Smith TM. Granular cell tumor of the breast: a series of 17 cases and review of the literature. Breast J. 2004;10(6):528–31.

    Article  PubMed  Google Scholar 

  78. Yang WT, Edeiken-Monroe B, Sneige N, Fornage BD. Sonographic and mammographic appearances of granular cell tumors of the breast with pathological correlation. J Clin Ultrasound. 2006;34(4):153–60.

    Article  PubMed  Google Scholar 

  79. Meani F, Di Lascio S, Wandschneider W, Montagna G, Vitale V, Zehbe S, et al. Granular cell tumor of the breast: a multidisciplinary challenge. Crit Rev Oncol Hematol. 2019;144:102828.

    Article  PubMed  Google Scholar 

  80. Szántó J, András C, Tsakiris J, Gomba S, Szentirmay Z, Bánlaki S, et al. Secretory breast cancer in a 7.5-year old boy. Breast. 2004;13(5):439–42.

    Article  PubMed  Google Scholar 

  81. Gutierrez JC, Housri N, Koniaris LG, Fischer AC, Sola JE. Malignant breast cancer in children: a review of 75 patients. J Surg Res. 2008;147(2):182–8.

    Article  PubMed  Google Scholar 

  82. Pietruszka M, Barnes L. Cystosarcoma phyllodes: a clinicopathologic analysis of 42 cases. Cancer. 1978;41(5):1974–83.

    Article  CAS  PubMed  Google Scholar 

  83. Nguyen NT, Maciolek LM, Qiu S, Sadruddin S, Nguyen QD. Malignant phyllodes tumor of the breast in a 26-year-old woman. Cureus. 2020;12(1):e6590.

    Google Scholar 

  84. Zhang Y, Kleer CG. Phyllodes tumor of the breast: Histopathologic features, differential diagnosis, and molecular/genetic updates. Arch Pathol Lab Med. 2016;140(7):665–71.

    Article  PubMed  Google Scholar 

  85. Liberman L, Bonaccio E, Hamele-Bena D, Abramson AF, Cohen MA, Dershaw DD. Benign and malignant phyllodes tumors: mammographic and sonographic findings. Radiology. 1996;198(1):121–4.

    Article  CAS  PubMed  Google Scholar 

  86. Tse GMK, Niu Y, Shi H-J. Phyllodes tumor of the breast: an update. Breast Cancer. 2010;17(1):29–34.

    Article  PubMed  Google Scholar 

  87. Joshi SC, Sharma DN, Bahadur AK, Maurya R, Kumar S, Khurana N. Cystosarcoma phyllodes: our institutional experience. Australas Radiol. 2003;47(4):434–7.

    Article  PubMed  Google Scholar 

  88. West KW, Rescorla FJ, Scherer LR, Grosfeld JL. Diagnosis and treatment of symptomatic breast masses in the pediatric population. J Pediatr Surg. 1995;30(2):182–6.

    Google Scholar 

  89. Murphy JJ, Morzaria S, Gow KW, Magee JF. Breast cancer in a 6-year-old child. J Pediatr Surg. 2000;35(5):765–7.

    Article  CAS  PubMed  Google Scholar 

  90. Stavros AT, Thickman D, Rapp CL, Dennis MA, Parker SH, Sisney GA. Solid breast nodules: use of sonography to distinguish between benign and malignant lesions. Radiology. 1995;196(1):123–34.

    Article  CAS  PubMed  Google Scholar 

  91. Venta LA, Dudiak CM, Salomon CG, Flisak ME. Sonographic evaluation of the breast. Radiographics. 1994;14(1):29–50.

    Article  CAS  PubMed  Google Scholar 

  92. Jackson VP. Sonography of malignant breast disease. Semin Ultrasound CT MR. 1989;10(2):119–31.

    CAS  PubMed  Google Scholar 

  93. Bhatia S, Robison LL, Oberlin O, Greenberg M, Bunin G, Fossati-Bellani F, et al. Breast cancer and other second neoplasms after childhood Hodgkin’s disease. N Engl J Med. 1996;334(12):745–51.

    Article  CAS  PubMed  Google Scholar 

  94. Lee CH, Dershaw DD, Kopans D, Evans P, Monsees B, Monticciolo D, et al. Breast cancer screening with imaging: recommendations from the Society of Breast Imaging and the ACR on the use of mammography, breast MRI, breast ultrasound, and other technologies for the detection of clinically occult breast cancer. J Am Coll Radiol. 2010;7(1):18–27.

    Article  PubMed  Google Scholar 

  95. Wu W-H, Ji Q-L, Li Z-Z, Wang Q-N, Liu S-Y, Yu J-F. Mammography and MRI manifestations of breast angiosarcoma. BMC Womens Health. 2019 10;19(1):73.

    Article  PubMed  PubMed Central  Google Scholar 

  96. Vorburger SA, Xing Y, Hunt KK, Lakin GE, Benjamin RS, Feig BW, et al. Angiosarcoma of the breast. Cancer. 2005;104(12):2682–8.

    Article  PubMed  Google Scholar 

  97. Yang WT, Hennessy BT, Dryden MJ, Valero V, Hunt KK, Krishnamurthy S. Mammary angiosarcomas: imaging findings in 24 patients. Radiology. 2007;242(3):725–34.

    Google Scholar 

  98. Dehner LP, Hill DA, Deschryver K. Pathology of the breast in children, adolescents, and young adults. Semin Diagn Pathol. 1999;16(3):​235–47.

    CAS  PubMed  Google Scholar 

  99. Liberman L, Dershaw DD, Kaufman RJ, Rosen PP. Angiosarcoma of the breast. Radiology. 1992;183(3):649–54.

    Article  CAS  PubMed  Google Scholar 

  100. Chen KT, Kirkegaard DD, Bocian JJ. Angiosarcoma of the breast. Cancer. 1980;46(2):368–71.

    Article  CAS  PubMed  Google Scholar 

  101. Varghese B, Deshpande P, Dixit S, Koppiker CB, Jalnapurkar N. Primary angiosarcoma of the breast: a case report. J Radiol Case Rep. 2019;13(2):15–25.

    PubMed  PubMed Central  Google Scholar 

  102. Howarth CB, Caces JN, Pratt CB. Breast metastases in children with rhabdomyosarcoma. Cancer. 1980;46(11):2520–4.

    Article  CAS  PubMed  Google Scholar 

  103. Rogers DA, Lobe TE, Rao BN, Fleming ID, Schropp KP, Pratt AS, et al. Breast malignancy in children. J Pediatr Surg. 1994;29(1):​48–51.

    Article  CAS  PubMed  Google Scholar 

  104. Yang WT, Metreweli C. Sonography of nonmammary malignancies of the breast. AJR Am J Roentgenol. 1999;172(2):343–8.

    Article  CAS  PubMed  Google Scholar 

  105. Sippo DA, Kulkarni K, Carlo PD, Lee B, Eisner D, Cimino-Mathews A, et al. Metastatic disease to the breast from extramammary malignancies: a multimodality pictorial review. Curr Probl Diagn Radiol. 2016;45(3):225–32.

    Google Scholar 

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Authors and Affiliations

  1. Edward B. Singleton Department of Radiology, Texas Children’s Hospital, Baylor College of Medicine, Houston, TX, USA

    Nadia Nagra-Mahmood

  2. Department of Radiology, Children’s Hospital Colorado, University of Colorado School of Medicine, Aurora, CO, USA

    Angie L. Miller

  3. Department of Radiology, University of Central Florida College of Medicine, Maitland, FL, USA

    Jennifer L. Williams

  4. Division of Ultrasound, Department of Radiology, Boston Children’s Hospital and Harvard Medical School, Boston, MA, USA

    Harriet J. Paltiel

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  1. Nadia Nagra-Mahmood
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  4. Harriet J. Paltiel
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Correspondence to Nadia Nagra-Mahmood .

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Editors and Affiliations

  1. Division of Ultrasound, Department of Radiology, Boston Children’s Hospital and Harvard Medical School, Boston, MA, USA

    Harriet J. Paltiel

  2. Division of Thoracic Imaging, Department of Radiology, Boston Children’s Hospital and Harvard Medical School, Boston, MA, USA

    Edward Y. Lee

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Nagra-Mahmood, N., Miller, A.L., Williams, J.L., Paltiel, H.J. (2021). Breast. In: Paltiel, H.J., Lee, E.Y. (eds) Pediatric Ultrasound. Springer, Cham. https://doi.org/10.1007/978-3-030-56802-3_20

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