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Endocrine Therapy

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Practical Medical Oncology Textbook

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Abstract

Hormone therapy can be a key strategy in the treatment of some neoplasms. The rational of this approach is based on the sensitivity of cancer cells due to the presence of specific receptors; for this reason they must be carefully investigated during histological analyses or with specific functional imaging techniques. They can be implied in different settings, i.e., pre- or postmenopause women with breast cancer: in these cases for the choice of the drug, these characteristics of patients must be held in consideration. A very peculiar condition is related to the onset of resistant mechanisms, which can be caused by the downregulation of the receptors. Hormonal therapy is nowadays used in case of breast, prostate, and neuroendocrine tumors with different results and benefits for the patients.

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Authors and Affiliations

  1. Medical Oncology Unit, Department of Clinical Medicine and Surgery, University of Naples “Federico II”, Naples, Italy

    Francesco Schettini, Giuseppe Buono, Mario Giuliano, Grazia Arpino & Sabino De Placido

  2. Lester and Sue Smith Breast Center at Baylor College of Medicine, Houston, TX, USA

    Mario Giuliano

Authors
  1. Francesco Schettini
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  2. Giuseppe Buono
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  3. Mario Giuliano
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  4. Grazia Arpino
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  5. Sabino De Placido
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Corresponding author

Correspondence to Sabino De Placido .

Editor information

Editors and Affiliations

  1. Department of Surgical, Oncological and Oral Sciences, University of Palermo, Palermo, Italy

    Antonio Russo

  2. Oncology Department, University of Antwerp, Edegem, Belgium

    Marc Peeters

  3. Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Palermo, Italy

    Lorena Incorvaia

  4. Center for Thoracic Oncology, Tisch Cancer Institute, Mount Sinai System & Icahn School of Medicine, Mount Sinai, NY, USA

    Christian Rolfo

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Schettini, F., Buono, G., Giuliano, M., Arpino, G., De Placido, S. (2021). Endocrine Therapy. In: Russo, A., Peeters, M., Incorvaia, L., Rolfo, C. (eds) Practical Medical Oncology Textbook. UNIPA Springer Series. Springer, Cham. https://doi.org/10.1007/978-3-030-56051-5_10

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  • DOI: https://doi.org/10.1007/978-3-030-56051-5_10

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-56050-8

  • Online ISBN: 978-3-030-56051-5

  • eBook Packages: MedicineMedicine (R0)

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