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The Neuropsychiatric Features of Behavioral Variant Frontotemporal Dementia

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Frontotemporal Dementias

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1281))

Abstract

Behavioral variant frontotemporal dementia (bvFTD) is a syndrome defined by a set of core clinical criteria, which include disinhibition; apathy or inertia; loss of sympathy or empathy; perseverative, stereotyped, or compulsive/ritualistic behavior; and hyperorality. The clinical features of bvFTD overlap substantially with those of psychiatric disease, particularly major depressive disorder and bipolar affective disorder. The similarities between bvFTD and primary psychiatric disease results in a significant diagnostic challenge for clinicians. Understanding the neuropsychiatric aspects of bvFTD may assist in differentiating bvFTD from a primary psychiatric disorder.

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Authors and Affiliations

  1. Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco School of Medicine, San Francisco, CA, USA

    Bradley T. Peet, Sheila Castro-Suarez & Bruce L. Miller

  2. Atlantic Fellow for Equity in Brain Health at UCSF and clinical researcher Instituto Nacional de Ciencias Neurológicas (INCN), Lima, Peru

    Sheila Castro-Suarez

Authors
  1. Bradley T. Peet
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  2. Sheila Castro-Suarez
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  3. Bruce L. Miller
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Corresponding author

Correspondence to Bradley T. Peet .

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Editors and Affiliations

  1. Department of Pathology and Laboratory Medicine, Indiana University, Indianapolis, IN, USA

    Bernardino Ghetti

  2. International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy

    Emanuele Buratti

  3. Department of Neurology, Mayo Clinic, Rochester, MN, USA

    Bradley Boeve

  4. VIB Center for Molecular Neurology University of Antwerp-CDE Antwerpen, Belgium, Department of Neuroscience Mayo Clinic Jacksonville, FL, USA, Antwerpen, Belgium

    Rosa Rademakers

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Peet, B.T., Castro-Suarez, S., Miller, B.L. (2021). The Neuropsychiatric Features of Behavioral Variant Frontotemporal Dementia. In: Ghetti, B., Buratti, E., Boeve, B., Rademakers, R. (eds) Frontotemporal Dementias . Advances in Experimental Medicine and Biology, vol 1281. Springer, Cham. https://doi.org/10.1007/978-3-030-51140-1_2

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