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Simultaneous EEG and fMRI Recordings (EEG–fMRI)

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fMRI

Abstract

Scalp electroencephalography (EEG) is characterised by a limited spatial resolution and by a low sensitivity to generators distant from the cortical surface. In contrast, fMRI is characterised by a good spatial resolution, and it is sensitive to the signal of deep brain structures. By combining EEG with functional magnetic resonance imaging (fMRI), it is possible to detect blood oxygenation level-dependent (BOLD) signal changes related to EEG patterns detected on the scalp: EEG-pattern-associated networks can be detected anywhere in the brain with a good spatial resolution. This chapter gives an introduction to the methodology of EEG–fMRI and summarises EEG–fMRI studies focused on epilepsy-related investigations: EEG–fMRI studies on focal epilepsy, generalised epilepsy and paediatric epilepsy are presented.

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Abbreviations

AAS:

Averaged artefact subtraction

BOLD:

Blood oxygenation level-dependent

EEG:

Electroencephalography

fMRI:

Functional magnetic resonance imaging

GSW:

Generalised spike-wave discharges

HRF:

Haemodynamic response function

IGE:

Idiopathic generalised epilepsy

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Authors and Affiliations

  1. Department of Neurophysiology, Great Ormond Street Hospital for Children, London, UK

    Friederike Moeller

  2. Clinic of Child and Adolescents Psychiatry and Psychotherapy, Ev. Hospital Bethel, Bielefeld, Germany

    Michael Siniatchkin

  3. Montreal Neurological Institute, McGill University, Montreal, QC, Canada

    Jean Gotman

Authors
  1. Friederike Moeller
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  2. Michael Siniatchkin
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  3. Jean Gotman
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Correspondence to Friederike Moeller .

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  1. Department of Radiology and Nuclear Medicine, Kantonsspital Winterthur, Winterthur, Switzerland

    Stephan Ulmer

  2. Department of Radiology and Neuroradiology, University Hospital Schleswig-Holstein, Kiel, Germany

    Olav Jansen

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Moeller, F., Siniatchkin, M., Gotman, J. (2020). Simultaneous EEG and fMRI Recordings (EEG–fMRI). In: Ulmer, S., Jansen, O. (eds) fMRI. Springer, Cham. https://doi.org/10.1007/978-3-030-41874-8_13

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  • DOI: https://doi.org/10.1007/978-3-030-41874-8_13

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