Abstract
Craniomaxillofacial (CMF) landmark localization is an important step for characterizing jaw deformities and designing surgical plans. However, due to the complexity of facial structure and the deformities of CMF patients, it is still difficult to accurately localize a large scale of landmarks simultaneously. In this work, we propose a three-stage coarse-to-fine deep learning method for digitizing 105 anatomical craniomaxillofacial landmarks on cone-beam computed tomography (CBCT) images. The first stage outputs a coarse location of each landmark from a low-resolution image, which is gradually refined in the next two stages using the corresponding higher resolution images. Our method is implemented using Mask R-CNN, by also incorporating a new loss function that learns the geometrical relationships between the landmarks in the form of a root/leaf structure. We evaluate our approach on 49 CBCT scans of patients and achieve an average detection error of 1.75 ± 0.91 mm. Experimental results show that our approach overperforms the related methods in the term of accuracy.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Zhan, Y., et al.: Robust automatic knee MR slice positioning through redundant and hierarchical anatomy detection. IEEE TMI 30(12), 2087–2100 (2011)
Criminisi, A., et al.: Regression forests for efficient anatomy detection and localization in computed tomography scans. MedIA 17(8), 1293–1303 (2013)
Payer, C., Štern, D., Bischof, H., Urschler, M.: Regressing heatmaps for multiple landmark localization using CNNs. In: Ourselin, S., Joskowicz, L., Sabuncu, M.R., Unal, G., Wells, W. (eds.) MICCAI 2016. LNCS, vol. 9901, pp. 230–238. Springer, Cham (2016). https://doi.org/10.1007/978-3-319-46723-8_27
Zhang, J., et al.: Joint craniomaxillofacial bone segmentation and landmark digitization by context-guided fully convolutional networks. In: Descoteaux, M., Maier-Hein, L., Franz, A., Jannin, P., Collins, D.L., Duchesne, S. (eds.) MICCAI 2017. LNCS, vol. 10434, pp. 720–728. Springer, Cham (2017). https://doi.org/10.1007/978-3-319-66185-8_81
Ren, S., et al.: Faster R-CNN: towards real-time object detection with region proposal networks. In: Advances in Neural Information Processing Systems, pp. 91–99 (2015)
He, K., et al.: Mask R-CNN. arXiv Preprint (2017)
Girshick, R.: Fast R-CNN. arXiv:1504.08083 (2015)
Yan, J., et al.: Three-dimensional CT measurement for the craniomaxillofacial structure of normal occlusion adults in Jiangsu, Zhejiang and Shanghai Area. China J. Oral Maxillofac. Surg. 8, 2–9 (2010)
Yuan, P., et al.: Design, development and clinical validation of computer-aided surgical simulation system for streamlined orthognathic surgical planning. Int. J. Comput. Assist. Radiol. Surg. 12, 2129–2143 (2017)
Lian, C., et al.: Multi-channel multi-scale fully convolutional network for 3D perivascular spaces segmentation in 7T MR images. MedIA 46, 106–117 (2018)
Lian, C., et al.: Hierarchical fully convolutional network for joint atrophy localization and Alzheimer’s disease diagnosis using structural MRI. IEEE TPAMI (2019)
Acknowledgment
This work was supported in part by NIDCR grants (DE022676 and DE027251).
Author information
Authors and Affiliations
Corresponding authors
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer Nature Switzerland AG
About this paper
Cite this paper
Lang, Y. et al. (2019). Automatic Detection of Craniomaxillofacial Anatomical Landmarks on CBCT Images Using 3D Mask R-CNN. In: Zhang, D., Zhou, L., Jie, B., Liu, M. (eds) Graph Learning in Medical Imaging. GLMI 2019. Lecture Notes in Computer Science(), vol 11849. Springer, Cham. https://doi.org/10.1007/978-3-030-35817-4_16
Download citation
DOI: https://doi.org/10.1007/978-3-030-35817-4_16
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-35816-7
Online ISBN: 978-3-030-35817-4
eBook Packages: Computer ScienceComputer Science (R0)