Abstract
Polyhydroxyalkanoates (PHAs) biopolymers provide a suitable alternative to the synthetic plastics because of their biodegradability, biocompatibility and environment friendly manufacturing processes. PHAs are promising candidate for bio-based plastics because their material properties are quite similar to petroleum-based plastics and can be produced from renewable resources. However, the high production cost limit their application at industrial level. This book chapter discusses about the challenges faced by the society for the commercialization of biodegradable PHAs.
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References
Alves MI et al (2017) Poly (3-hydroxybutyrate)-P (3HB): review of production process technology. Ind Biotechnol 13(4):192–208
Braunegg G, Bona R, Koller M (2004) Sustainable polymer production. Polym Plast Technol Eng 43(6):1779–1793
Castilho LR, Mitchell DA, Freire DMG (2009) Production of polyhydroxyalkanoates (PHAs) from waste material and solid-state fermentation. Bioresour Technol 100:5996–6009
Cavalheiro JMBT et al (2012) Effect of cultivation parameters on the production of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) and poly(3-hydroxybutyrate-4-hydroxybutyrate-3-hydroxyvalerate) by Cupriavidus necator using waste glycerol. Bioresour Technol 111:391–397
Chanprateep S (2010) Current trends in biodegradable polyhydroxyalkanoates. J Biosci Bioeng 110(6):621–632
Domski GJ, Rose JM, Coates GW, Bolig AD, Brookhart M (2007) Living alkene polymerization: new methods for the precision synthesis of polyolefins. Prog Polym Sci 32:30–92
Fiorese ML, Freitas F, Pais J, Ramos AM, de Aragão GM, Reis MA (2009) Recovery of polyhydroxybutyrate (PHB) from Cupriavidus necator biomass by solvent extraction with 1,2-propylene carbonate. Eng Life Sci 9(6):454–461
Gomez JG, Méndez BS, Nikel PI, Pettinari MJ, Prieto MA, Silva LF (2012) Making green polymers even greener: towards sustainable production of polyhydroxyalkanoates from agroindustrial by-products. (ed by Marian Petre) Adv Appl Biotechnol 41–62
Ienczak JL, Schmidell W, de Aragão GMF (2013) High-cell-density culture strategies for polyhydroxyalkanoate production: a review. J Ind Microbiol Biotechnol 40(3–4):275–286
Jacquel N, Lo C-W, Wei Y-H, Wu H-S, Wang SS (2008) Isolation and purification of bacterial poly(3-hydroxyalkanoates). Biochem Eng J 39(1):15–27
Kim M, Cho KS, Ryu HW, Lee EG, Chang YK (2003) Recovery of poly (3-hydroxybutyrate) from high cell density culture of Ralstonia eutropha by direct addition of sodium dodecyl sulfate. Biotechnol Lett 25:55–59
Koller M et al (2008) Polyhydroxyalkanoate production from whey by Pseudomonas hydrogenovora. Bioresour Technol 99:4854–4863
López-Abelairas M, GarcÃa-Torreiro M, Lú-Chau T, Lema JM, Steinbüchel A (2015) Comparison of several methods for the separation of poly (3-hydroxybutyrate) from Cupriavidus necator H16 cultures. Biochem EngJ 93:250–259
Nath A, Dixit M, Bandiya A, Chavda S, Desai AJ (2008) Enhanced PHB production and scale up studies using cheese whey in fed batch culture of Methylobacterium sp. ZP24. Bioresour Technol 99(13):5749–5755
Pan W, Perrotta JA, Stipanovic AJ, Nomura CT, Nakas JP (2012) Production of polyhydroxyalkanoates by Burkholderia cepacia ATCC 17759 using a detoxified sugar maple hemicellulosic hydrolysate. J Ind Microbiol Biotechnol 39:459–469
Penloglou G, Chatzidoukas C, Kiparissides C (2012) Microbial production of polyhydroxybutyrate with tailor-made properties: an integrated modelling approach and experimental validation. Biotechnol Adv 30(1):329–337
Wang Y, Chen G-Q (2017) Polyhydroxyalkanoates: sustainability, production and industrialization. In: Tang C, Ryu CY (eds) Sustainable polymers from biomass. Wiley VCH, Weinheim, Germany, p 14
Wang Y, Yin J, Chen G-Q (2014) Polyhydroxyalkanoates, challenges and opportunities. Curr Opin Biotechnol 30:59–65
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Gahlawat, G. (2019). Challenges in PHAs Production at Mass Scale. In: Polyhydroxyalkanoates Biopolymers. SpringerBriefs in Molecular Science(). Springer, Cham. https://doi.org/10.1007/978-3-030-33897-8_3
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DOI: https://doi.org/10.1007/978-3-030-33897-8_3
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