Abstract
Photothermal therapies rely on various types of optically active nanomaterials, such as carbon, silicon, titanium dioxide, iron-based, polymeric, and rare earth-doped nanomaterials, which are aiming to convert light into heat. However, lack of clear guidelines and standardized approaches to determine their photothermal properties hinders quantitative comparison between them and impedes focusing on the most promising ones. Therefore, the major motivation for this chapter is to highlight the recent progress, constrained to last 5 years, in the field of non-plasmonic photothermal agents activated in NIR spectral range, to qualitatively compare wide selection of available materials and to essay a quantitative comparison by adopting a simple, but effective approach. Moreover, the advantages and disadvantages of different photothermal agents were discussed in terms of their cytotoxicity, easiness of their biofunctionalization, and the minimal dose for efficient heat generation.
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Acknowledgments
A.B. acknowledges the FET Open project that has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 801305. K.K and K.E acknowledge “High sensitive thermal imaging for biomedical and microelectronic application” project is carried out within the First Team program of the Foundation for Polish Science co-financed by the European Union under the European Regional Development Fund.
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Marciniak, L., Kniec, K., Elzbieciak, K., Bednarkiewicz, A. (2020). Non-plasmonic NIR-Activated Photothermal Agents for Photothermal Therapy. In: Benayas, A., Hemmer, E., Hong, G., Jaque, D. (eds) Near Infrared-Emitting Nanoparticles for Biomedical Applications. Springer, Cham. https://doi.org/10.1007/978-3-030-32036-2_12
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