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Adult and Childhood Vasculitis of the Nervous System

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Clinical Neuroimmunology

Part of the book series: Current Clinical Neurology ((CCNEU))

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Abstract

The vasculitides are heterogeneous clinicopathologic disorders that share the common features of vascular inflammation. The resulting disorders vary depending upon the involvement of specific organs, the caliber of vessels, the underlying inflammatory process, and individual host factors. The cumulative result is diminished blood flow, vascular alterations, and eventual occlusion with variable ischemia, necrosis, and tissue damage. An international revised nomenclature system based upon the current state of knowledge provides clinicians and investigators with the necessary nosology and findings relevant to each of the vasculitides. It has been nearly a century since vasculitis was first described. This chapter reviews historical aspects, nosology, classification, clinical and laboratory presentation, and treatment of adult and childhood systemic and nervous system vasculitis.

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Authors and Affiliations

  1. Department of Neurology, White Plains Hospital, New York, NY, USA

    David S. Younger

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  1. David S. Younger
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  1. Rhode Island Hospital and Alpert Medical School of Brown University, Brown Neurology, Providence, RI, USA

    Syed A. Rizvi

  2. Rhode Island Hospital and Alpert Medical School of Brown University, Brown Neurology, Providence, RI, USA

    Jonathan F. Cahill

  3. Department of Neurology, MS Comprehensive Care Center, Stony Brook University Medical Center, Stony Brook, NY, USA

    Patricia K. Coyle

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Younger, D.S. (2020). Adult and Childhood Vasculitis of the Nervous System. In: Rizvi, S., Cahill, J., Coyle, P. (eds) Clinical Neuroimmunology. Current Clinical Neurology. Humana, Cham. https://doi.org/10.1007/978-3-030-24436-1_14

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