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Abstract

The Cuyo region has diverse landscapes; there are high mountain ranges, mountains, and valleys. Its vegetation is characteristic of an arid region with predominance of xerophilous plants. There are more than 150 species with folk medicinal uses described for this region. Among them, Aloysia gratissima (Gillies & Hook. ex Hook.) Tronc., Lippia integrifolia (Griseb.) Hieron., Minthostachys mollis, Acantholippia seriphioides (A. Gray) Moldenke, and Achyrocline satureioides (Lam.) DC. are described in this chapter with respect to their botanical characteristics, ethnomedical uses, chemicals, biological activity, toxicity, and establishment of in vitro cultures and legal status, when corresponding.

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References

  • Agüero E (2017) Plantas medicinales silvestres del centro de Argentina. Guía para su reconocimiento y uso terapéutico. Editorial Ecoval, Unquillo, Córdoba, Argentina

    Google Scholar 

  • Alonso J, Desmarchelier C (2015) Plantas medicinales. Bases científicas para su aplicación en atención primaria de la salud. Ed. Corpus, Buenos Aires

    Google Scholar 

  • Andersen A, Carosio C, Junqueras M (1997) Principales plantas medicinales de la Provincia de San Luis. Anales de Saipa 15:217–227

    Google Scholar 

  • Anesini C, Pérez C (1993) Screening of plants used in Argentine folk medicine for antimicrobial activity. J Ethnopharmacol 39(2):119–128

    Article  CAS  PubMed  Google Scholar 

  • Argentina Food Code (2013) Chapter XV, Art.1192 bis (res. SPReI & SAGyP, N° 25/2011 &N° 64/2011)

    Google Scholar 

  • Balestrini LA, Bidone J, Bertolin RC, Moresco K, Moreira JC, Teixeira HF (2016) Protective effect of a hydrogel containing Achyrocline satureioides extract-loaded nano emulsion against UV-induced skin damage. J Photochem Photobiol B Biol 163:269–276

    Article  CAS  Google Scholar 

  • Bandoni AL, Lopez MA, Juárez MA, Elechosa MA, van Baren CM, Di Leo LP (2002) Seasonal variations in the composition of the essential oil of “peperina” (Minthostachys mollis (Kunth) Griseb.) from a local population of the Province of Cordoba, Argentina. Essenze Deriv Agrum 72:11–14

    CAS  Google Scholar 

  • Barboza GE, Cantero JJ, Núñez C, Pacciaroni A, Ariza Espinar L (2009) Medicinal Plants: A general review and a phytochemical and ethnopharmacological screening of the native Argentine Flora. Kurtziana 34(12):7365

    Google Scholar 

  • Barioni ED, Santin JR, Daufenback Machado I, Fernandes de Paula Rodrigues S, Ferraz-de-Paula V, Wagner TM, Cogliati B, Correa dos Santos M, Da Silva Machado M, Faloni de Andrade S, Niero R, Poliselli Farsky H (2013) Achyrocline satureioides (Lam.) D.C. Hydroalcoholic extract inhibits neutrophil functions related to innate host defense. Evid Based Complement Alternat Med 2013, Article ID 787916, 12 pages. https://doi.org/10.1155/2013/787916

    Article  Google Scholar 

  • Bassols GB, Gurni AA (1996) Lippia species employed in Latin America folk medicine. Dominguezia 13(1):7–25

    Google Scholar 

  • Benovit SC, Silva LL, Salbego J, Loro VL, Mallmann CA, Baldisserotto B, Flores EMM, Heinzmann BM (2015) Anesthetic activity and bio-guided fractionation of the essential oil of Aloysia gratissima (Gillies & Hook.) Tronc. in silver cat-fish Rhamdia quelen. An Acad Bras Cienc 87(3):1675–1689. https://doi.org/10.1590/0001-3765201520140223

    Article  CAS  PubMed  Google Scholar 

  • Bernasconi Salazar JR, Karlin M, Arnulphi AS, Karlin UO, Accietto RH, Cora A (2017) Plantas del centro de la República Argentina: guia de campo, 1ª edn. Ecoval Editorial. Córdoba

    Google Scholar 

  • Bidone J, Bica VC, Petrovick PR, Simões KLS, Bassani VL, Teixeira HF (2014) Simultaneous quantification of flavonoids from Achyrocline satureioides by a polar-reversed phase LC method — application to skin permeation/retention studies. Pharmazie 69:5–9

    CAS  PubMed  Google Scholar 

  • Bidone J, Fretes Argenta D, Kratz J, Ferreira Pettenuzzo L, Horn AP, Scherer Koester L, Linck Bassani V, Oliveira Simões CM, Ferreira TH (2015) Anti-herpes activity and skin/Mucosa distribution of flavonoids from Achyrocline satureioides extract incorporated into topical nanoemulsions. BioMed Res Int 2015:238010, 7 pages. https://doi.org/10.1155/2015/238010

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Blasina MF, Vaamonde L, Morquio A, Echeverry C, Arredondo F, Dajas F (2009) Differentiation Induced by Achyrocline satureioides (Lam) Infusion in PC12 Cells. Phytother Res 23:1263–1269

    Article  CAS  PubMed  Google Scholar 

  • Bluma R, Etcheverry M (2008) Application of essential oils in maizegrain: impact on Aspergillus section Flavi growth parameters and aflatoxin accumulation. Food Microbiol 25:324–334

    Article  CAS  PubMed  Google Scholar 

  • Bluma R, Amaiden MR, Etcheverry M (2008a) Screening of Argentine plant extracts: Impact on growth parameters and aflatoxin B1 accumulation by Aspergillus section Flavi. Int J Food Microbiol 122:114–125

    Article  CAS  PubMed  Google Scholar 

  • Bluma R, Amaiden MR, Daghero J, Etcheverry M (2008b) Control of Aspergillus section Flavi growth and aflatoxin accumulation by plant essential oils. J Appl Microbiol 105:203–214

    Article  CAS  PubMed  Google Scholar 

  • Braga MEM, Perucho MP, Quispe-Condori S, Rosa PTV, Meireles MAA (2006) Phenolic Compounds Extraction from Achyrocline satureioides, Curcuma longa, Foeniculum vulgare and Rosmarinus officinalis. J Agri Food Chem 43:401–407

    Google Scholar 

  • Bustos DA, Tapia AA, Feresin GE (1996) Ethnopharmacobotanical survey of Baichazeta district, San Juan Provine, Argentina. Fitoterapia 67(5):411–415

    Google Scholar 

  • Cabrera AL, Zardini EM (1978) Manual de la Flora de los alrededores de Buenos Aires, 2nd edn. Editorial ACME SACI, Buenos Aires

    Google Scholar 

  • Calvo D, Cariddi LN, Grosso M, Demo MS, Maldonado AM (2006) Achyrocline satureioides (Lam.) DC (Marcela): Antimicrobial activity on Staphylococcus spp. and immunomodulating effects on human lymphocytes. Rev Latinoam Microbiol 48(3–4):247–255

    CAS  PubMed  Google Scholar 

  • Campagnol PCB, Fries LLM, Terra NN, dos Santos BA, Furtado AS, Toneto ERL, de Campos RML (2011) The influence of Achyrocline satureioides (“Marcela”) extract on the lipid oxidation of salami. Ciênc Tecnol Aliment Campinas 31(1):101–105

    Article  Google Scholar 

  • Cané L (2016) Plantas nativas. Las especies y su cultivo. Ediciones Jardín, Edit, Catapulta, Buenos Aires

    Google Scholar 

  • Cariddi LN (2013) The role of essential oil of Minthostachys verticillata (Griseb) Epling, (Lamiaceae) and its active metabolites in immediate-type hypersensitivity responses. In: Govil JN, Bhattacharya S (eds) Recent progress in medicinal plants essential oils II. Studium Press, LLC, Houston, pp 487–495

    Google Scholar 

  • Cariddi L, Escobar F, Moser M, Panero A, Alaniz F, Zygadlo J, Sabini L, Maldonado A (2011) Monoterpenes isolated from Minthostachys verticillata (Griseb.) Epling essential oil modulates immediate-type hypersensitivity responses in vitro and in vivo. Planta Med 77(15):1687–1694

    Article  CAS  PubMed  Google Scholar 

  • Cariddi LN, Sabini MC, Escobar FM, Bacchetti R, Montironi I, Merckis C, Reinoso EB, Núñez Montoya S, Zanon SM, Comini LR, Sabini LI (2015) In vitro and in vivo cytogenotoxic effects of hot aqueous extract of Achyrocline satureioides (Lam.) DC. BioMed Research International 2015:270973, 12 pages. https://doi.org/10.1155/2015/270973

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Carini JP, Kaaiser S, Ortega GG, Bassani VL (2012) Development, optimisation and validation of a stability-indicating HPLC method of achyrobichalcone quantification using experimental designs. Phytochem Anal 24(3):193–200

    Article  CAS  PubMed  Google Scholar 

  • Carini JP, Klamt F, Linck Bassani V (2014) Flavonoids from Achyrocline satureioides: promising biomolecules for anticancer therapy. RSC Adv 4:3131–3144

    Article  CAS  Google Scholar 

  • Carini JP, Leitão GG, Schneider PH, Santos CC, Costa FN, Holzschuh MH, Klamts F, Bassani VL (2015) Isolation of achyrobichalcone from Achyrocline satureioides by high- speed countercurrent chromatography. Curr Pharm Biotechnol 16:66–71

    Article  CAS  PubMed  Google Scholar 

  • Carney JR, Krenisky JM, Williamson RT, Luo J (2002) Achyrofuran, a New Antihyperglycemic Dibenzofuran from the South American Medicinal Plant Achyrocline satureioides. J Nat Prod 65(2):203–205

    Article  CAS  PubMed  Google Scholar 

  • Caro JA (1982) Sistematización del género Acantholippia grisebach (Verbenaceae) y las especies de la Flora Argentina. Domingezia 3:1–31

    Google Scholar 

  • Casero C, Machín F, Méndez-Álvarez S, Demo M, Ravelo AG, Pérez-Hernández N, Joseph-Nathan P, Estévez-Braun A (2014) Structure and antimicrobial activity of Phloroglucinol derivatives from Achyrocline satureioides. J Nat Prod 78(1):93–102

    Article  CAS  PubMed  Google Scholar 

  • Catalán CA, Iglesias DI, Retamar JA, Iturraspe JB, Dartayet GH, Gros EG (1983) A sesquiterpene diketone from Lippia integrifolia. Phytochemistry 22(6):1507–1508

    Article  Google Scholar 

  • Catalán CAN, de Fenik IJS, Dartayet GH, Gros EG (1991) Integrifolian-1,5-dione and a revised structure for “africanone” biogenetically related sesquterpene ketones from Lippia integrifolia. Phytochemistry 30(4):1323–1326

    Article  Google Scholar 

  • Catalan CAN, de Fenik IJS, de Arriazu PJ, Kokke CMC (1992) 4,5-seco-african-4,5-dione from Lippia integrifolia. Phytochemistry 31(11):4025–4026

    Article  CAS  Google Scholar 

  • Cosentino M, Bombelli Rm Carcano E, Luini A, Marino F, Crema F, Dajas F, Lecchini S (2008) Immunomodulatory properties of Achyrocline satureioides (Lam.) D.C. infusion: a study on human leukocytes. J Ethnopharmacol 116:501–507

    Article  PubMed  Google Scholar 

  • Dartayet GH, Catalán CA, Retamar JA, Gros EG (1984) Sesquiterpenoids from Lippia integrifolia-africanone, a tricyclic sesquterpene ketone. Phytochemistry 23(3):688–689

    Article  CAS  Google Scholar 

  • de Feo V, Ricciardi A, Biscardi D (1998) Chemical composition and antimicrobial screening of the essential oil of Minthostachys verticillata (Griseb.) Epl. (Lamiaceae). J Essent Oil Res 10:61–65

    Article  Google Scholar 

  • De Souza KCB, Schapoval EES, Bassani VL (2002) LC determination of flavonoids: separatin of quercetin, luteolin and 3-0-methylquercetin in Achyrocline satureioides preparations. J Pharm Biomed Anal 28(3–4):771–777

    Article  PubMed  Google Scholar 

  • Del Vitto LA, Petenatti EM, Petenatti ME (1997) Recursos herbolarios de San Luis (República Argentina) Primera parte: plantas nativas. Multequina 6:49–66

    Google Scholar 

  • Delucchi G (2006) Las especies vegetales amenazadas de la Provincia de Buenos Aires: Una actualización. APRONA Bol Cient 39:19–31

    Google Scholar 

  • Demo M, Ceriatti F, Sabini L, Zanón S, Sutil S, Grosso M, Ferreyra S, Ramos B (1998) Relevamiento de plantas medicinales del sur de la provincia de Córdoba con actividad antimicrobiana. 3er. Encuentro Regional del NOA de Plantas Medicinales. 7–9 de mayo de 1998. Santiago del Estero, Argentina

    Google Scholar 

  • Desmarchelier C, Coussio J, Ciccia G (1998) Antioxidant and free radical scavenging effects in extracts of the medicinal herb Achyrocline satureioides (Lam.) DC (AS). Braz J Med Biol Res 31(9):1163–1170

    Article  CAS  PubMed  Google Scholar 

  • Do Carmo G, Baldissera MD, Vaucher RA, Rech VC, Oliveira CB, Rorato Sagrillo M, Boligon AA, Athayde ML, Alves MP, França RT, Lopes STA, Schwertz C, Mendes RE, Monteiro SG, DA Silva AS (2015) Effect of the treatment with Achyrocline satureioides (free and nanocapsules essential oil) and diminazene aceturate on hematological and biochemical parameters in rats infected by Trypanosoma evansi. Exp Parasitol 149:39–46

    Article  CAS  PubMed  Google Scholar 

  • Domínguez J (1928) Materia Médica Argentina. Edit. Peuser, Buenos Aires

    Google Scholar 

  • Duarte M, Figueira G, Pereira B, Magalhães PE Delarmelina C (2004) Atividade antimicrobiana do extrato hidroalcoólico de espécies da coleção de plantas medicinais do CPQBA/Unicamp. Abstract FT-23. III° Congresso Ibero-Americano de Plantas Medicinais. 20–23 de maio de 2004. Rio de Janeiro

    Google Scholar 

  • Duschatzky CB, Martínez AN, Almeida NV, Bonivardo SL (2004) The nematicidal activity of the essential oils isolated from Aloysia triphylla, A. polystachya, A. gratissima, Lippia Argentina plants against the root-knot nematode. J Essent Oil Res 16:626–628

    Article  CAS  Google Scholar 

  • Elechosa MA, Molina AM, Juárez MA, van Baren CM, Di Leo LP, Bandoni AL (2007) Estudio comparativo del aceite esencial de Minthostachys mollis (Kunth.) Griseb., “peperina”, obtenido de colectas en 21 poblaciones de las provincias de Tucumán, Cordoba, San Luis y Catamarca. Bol. Latinoam. Caribe Plant. Med. Aromaticas 6:244–245

    Google Scholar 

  • Elechosa MA, Aguirre E, Bandoni AL, Di Leo Lira PMR, Fernández EA, Heit C, Juárez MA, López S, Martínez A, Martínez E, Marino AM, Molina AC, van Baren CM, Viturro CI (2009) Manual de recolección sustentable de plantas aromáticas nativas de la regióncentral y noroeste de la Argentina. Ed. INTA, Buenos Aires

    Google Scholar 

  • Epling C (1939) Las Labiadas en el Noroeste de la Argentina. Lilloa 4:434–435

    Google Scholar 

  • Escobar FM, Cariddi LN, Sabini MC, Reinoso E, Sutil SB, Torres CV, Zanon SM, Sabini LI (2012) Lack of cytotoxic and genotoxic effects of Minthostachys verticillata essential oil: Studies in vitro and in vivo. Food Chem Toxicol 50:3062–3067

    Article  CAS  PubMed  Google Scholar 

  • Escobar FM, Sabini MC, Cariddi LN, Sabini MC, Mañas FJ, Cristofolini AL, Bagnis G, Gallucci MN, Cavaglieri LR (2015) Safety assessment of essential oil from Minthostachys verticillata (Griseb.) Epling (peperina): 90-Days oral subchronic toxicity study in rats. Regulat Toxicol Pharmacol Rtp 71(1):1–7

    Article  CAS  Google Scholar 

  • Farahani MS, Bahramsoltani R, Farzaei MH, Abdollahi M, Rahimi R (2014) Antidepressant plants and their mechanisms of action: a review of literature. Pharmaceutical sciences 20 (supll 1) 18 18th Iranian Pharmacy Student Seminar. http://pharm-sci.tbzmed.ac.ir

  • Fester GA, Martinuzzi EA (1950) La esencia de peperina. 2a comunicación. An Asoc Quím Argent 38:255–267

    CAS  Google Scholar 

  • Fester GA, Martinuzzi EA, Retamar JA, Ricciardi AIA (1960) Estudios sobre esencias volátiles argentinas. Revista de la Facultad de Ingeniería Quimica 29:21–44

    CAS  Google Scholar 

  • Franco ALP, Oliveira TB, Ferri PH, Bara MTF, de Paula JR (2007) Avaliação da composição química e atividade antibaceriana dos óleos essenciais de Aloysia gratissima (Gillies and Hook) Tronc. (alfazema), Ocium gratissimum L. (alfavaca-cravo) e Curcuma longa L. (açafrao). Rev Eletronica Farm 4:208–220

    Google Scholar 

  • Fuselli SR, Garcia de la Rosa SB, Eguaras MJ, Fritz R, Ndagijimana M, Vannini L, Guerzoni ME (2007) Efficacy of indigenous plant essential oil Andean Thyme (Acantholippia seriphioides A. Gray) to control American Foulbrood (AFB) in honey bee (Apis mellifera L.) hives. J Essent Oil Res 19:514–519

    Article  CAS  Google Scholar 

  • García C, Talarico L, Almeida N, Colombres S, Duschatzky C, Damonte E (2003) Virucidal activity of essential oils from aromatic plants of San Luis, Argentina. Phytother Res 17(9):1073–1075

    Article  CAS  PubMed  Google Scholar 

  • Gastaldi B, Assef Y, van Baren C, Di Leo LP, Retta D, Bandoni AL, González SB (2016) Actividad antioxidante en infusiones, tinturas y aceites esenciales de especies nativas de la Patagonia Argentina. Revista Cubana de Plantas Medicinales 21(1):51–62

    Google Scholar 

  • Gattuso S, Scandizzi A, Busilacchi H, Di Sapio O, Severin C (2006) Achyrocline satureioides (Lam,) DC.: propagación in vitro a partir de segmentos nodales. Revista de Investigaciones de la Facultad de Ciencias Agrarias-UNR VII(11):45–50

    Google Scholar 

  • Gattuso S, Scandizzini A, Busilacchi H, Di Sapio O, Severin C (2007) Achyrocline satureioides (Lam.) DC: Propagagación in vitro a partir de segmentos nodales. Rev Inv Fac Cs Agrarias 11:45–50

    Google Scholar 

  • Gattuso M, Cortadi A, Mc Cargo J, Retta D, Bandoni A, Ferraro G, Gattuso S (2008) Estudio morfoanatómico vegetativo y floral de Achyrocline satureioides; Achyrocline flaccida y Gnaphalium gaudichaudianum (Asteraceae) Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas BLACPMA. 7(4):193–194

    Google Scholar 

  • Gillij YG, Gleiser RM, Zygadlo JA (2008) Mosquito repellent activity of essential oils of aromatic plants growing in Argentina. Bioresour Technol 99:2507–2515

    Article  CAS  PubMed  Google Scholar 

  • Gleiser R, Bonino M, Zygadlo J (2011) Repellence of essential oils of aromatic plants growing in Argentina against Aedes aegypti (Diptera: Culicidae). Parasitol Res 108:69–78

    Article  PubMed  Google Scholar 

  • González MJ, Marioli JM (2010) Antibacterial activity of water extracts and essential oils of various aromatic plants against Paenibacillus larvae, the causative agent of American Foulbrood. J Invertebr Pathol 104(3):209–213

    Article  CAS  PubMed  Google Scholar 

  • González S, Molares S (2004) Plantas Medicinales Utilizadas en Comunidades Rurales del Chubut, Patagonia Argentina. Bol Latinoam Caribe Plant Med Aromat 3:58–62

    Google Scholar 

  • González Pereyra ML, Cariddi LN, Ybarra F, Isola MC, Demo MS, Sabini LI, Maldonado AM (2005) Immunomodulating properties of Minthostachys verticillata on human lymphocytes and basophils. Rev Alergia Mexico 52(3):105–112

    Google Scholar 

  • Gorzalczany S, Sülsen V, Redko F, Vescina C, Muschietti L, Martino V, Acevedo C (2008) Choleretic and antispasmodic effects of Lippia integrifolia aqueous extract. Braz J Pharmacognosy 18:16–20

    CAS  Google Scholar 

  • Grassi-Zampieron RF, França LV, Carollo CA, do Carmo Vieira M, Oliveiros-Bastidas A, de Siqueira JM (2009a) Comparative profiles of Achyrocline alata (Kunth) DC. and A. satureioides (Lam.) DC., Asteraceae, applying HPLC-DAD-MS. Revista Brasileira de Farmacognosia Brazilian Journal of Pharmacognosy 20(4):575–579

    Article  Google Scholar 

  • Grassi-Zampieron RF, Vieira MC, de Siquera JA (2009b) Atividade antioxidante e captora de radicais livres dos extratos de Achyrocline alata (Kunth.) DC. em comparação com extratos de Achyrocline satureioides (Lam.) DC. Revista Brasileira de Farmacognosia Brazilian Journal of Pharmacognosy 19(2B):572–576

    Article  CAS  Google Scholar 

  • Haene E (2007) 100 Flores Argentinas. Ed. Albatros, Buenos Aires

    Google Scholar 

  • Hieronymus J (1882) Plantae Diaphoricae Florae Argentinae. Edit. Peuser, Buenos Aires

    Google Scholar 

  • Hister CAL, Laughingho HD, Da Silva CB, Do Canto Dorow TS, Tedesco SB (2009) Evaluation of the Antiproliferative effect of infusions and essential oil of Aloysia gratissima. Pakistan J Biol Sci 12(24):1581–1584

    Article  CAS  Google Scholar 

  • Holzschuh MH, Gosmann G, Schneider PH, Schapoval EES, Bassani VL (2010) Identification and stability of a new bichalcone in Achyrocline satureioides spray dried powder. Pharmazie 65:650–656

    CAS  PubMed  Google Scholar 

  • Ianicelli J, Pérez de la Torre M, Coviella A, Del Valle AE, Elechosa MA, van Baren CM, Pacheco MG, Escandón AS (2016) In vitro propagation of Lippia integrifolia (Griseb.) Hier. and detection of genetic instability through ISSR markers of in vitro-cultured plants. Rev Fac Agronom, La Plata 115(1):67–76

    Google Scholar 

  • Joray MB, Palacios SM, Carpinella MC (2013) Understanding the interactions between metabolites isolated from Achyrocline satureioides in relation to its antibacterial activity. Phytomedicine 20:258–261

    Article  CAS  PubMed  Google Scholar 

  • Kadarian C, Broussalis AM, Miño J, Lopez P, Gorzalczany S, Ferraro G, Acevedo C (2002) Hepatoprotcctive activity of Achyrocline satureioides (Lam) D. C. Pharmacol Res 45:57–61

    Article  CAS  PubMed  Google Scholar 

  • Labuckas DO, Maestri DM, Grosso NR, Zygadlo JA (1999) Essential oils of Achyrocline satureioides, Achyrocline alata and Achyrocline tomentosa. Planta Med 65:184–186

    Article  CAS  PubMed  Google Scholar 

  • Lima B, López S, Luna L, Aguero MB, Aragon L, Tapia A, Zacchino S, López ML, Zygadlo J, Feresin GE (2011) Essential Oils of Medicinal Plants from the Central Andes of Argentina: Chemical Composition, and Antifungal, Antibacterial, and Insect-Repellent Activities. Chem Biodivers 8:924–936

    Article  CAS  PubMed  Google Scholar 

  • Maciel MJ, Silva da Sliva MA, Ethur E, Marchionatti Avancin CA (2017) Phytochemical indicators and antibacterial activity of the crude hydroalcoholic extract of Achyrocline satureioides ("macela") against antibiotic-resistant Salmonella spp. isolated from animal products (swine and poultry). Revista Brasileira de Higiene e Sanidade Animal 11(3):273–287

    Article  Google Scholar 

  • Marcial G, Sendker J, Brandt S, Perotti de Lampasona M, Catalán CAN, Font de Valdez G, Hensel A (2014) Gastroprotection as an example: Antiadhesion against Helicobacter pylori, anti-inflammatory and antioxidante activities of aqueous extracts from the aerial parts of Lippia integrifolia Hieron. J Ethnopharmacol 155:1125–1133

    Article  PubMed  Google Scholar 

  • Marcial G, de Lampasona MP, Veja MI, Lizarraga E, Viturro CI, Slanis A, Juárez MA, Elechosa MA, Catalán CAN (2016) Intraspecific variation in essential oil composition of the medicinal plant Lippia integrifolia (Verbenaceae). Evid Five Chemotypes Phytochem 122:203–212

    Article  CAS  Google Scholar 

  • Martínez Carretero E (2013) Flora de Mendoza. Multequina 22(5):1–3

    Google Scholar 

  • Martínez Crovetto R (1981) Fertility-regulating plants used in popular medicine in Northeastern Argentina. Parodiana 1:97–117

    Google Scholar 

  • Massori L, Yazdani S, Rezaei F, Amraei M (2017) Phytotherapy for Streptococcus viridians. J Pharm Sci Res 9(7):1205–1208

    Google Scholar 

  • Moresco KS, Silveira AK, Zeidán-Chuñiá F, Fonseca Correia AP, Oliveria RR, Borges AG, Grun L, Barbé-Tuana F, Zmozinski A, Brandelli A, Goretti Rodrigues Vale M, Pens Gelain D, Link Bassani V, Fonseca Moreira JC (2017) Effects of Achyrocline satureioides inflorescence extracts against pathogenic intestinal bacteria: chemical characterization, in vitro tests, and in vivo evaluation. Evid Based Complement Alter Med 2017:4874865, 10 pages. https://doi.org/10.1155/2017/4874865

    Article  Google Scholar 

  • Mota FM, Carvalho HH, Wiest JM (2011) Atividade antibacteriana in vitro de inflorescências de Achyrocline satureioides (Lam.) DC. – Asteraceae (“macela”, “marcela”) sobre agentes bacterianos de interesse em alimentos. Rev Bras Pl Med Botucatu 13(3):298–304

    Article  Google Scholar 

  • Múlgura de Romero ME, Martínez SG, Atkins S, Rotman AD (2002) Morfología de las inflorescencias en Verbenáceae, Verbenoideae III: Tribu Lantaneae Darwinina. Nueva Serie 40(1–4):1–15

    Google Scholar 

  • Murashige T, Skoog F (1962) A revised medium for rapid growth and bio assays with tobacco tissue cultures. Physol Plant 15:473–497

    Article  CAS  Google Scholar 

  • Muschietti L, Derita M, Sülsen V, de Dios MJ, Ferraro G, Zacchino S, Martino V (2005) In vitro antifungal assay of traditional Argentine medicinal plants. J Ethnopharmacol 102(2):233–238

    Article  PubMed  Google Scholar 

  • Núñez C, Cantero J (2000) Las plantas medicinales del sur de la provincia de Córdoba. Edit. Universidad Nacional de Río Cuarto, Argentina

    Google Scholar 

  • O’Leary N, Lu-Irving P, Moroni P, Siedo S (2016) Taxonomic revision of Aloysia (Verbenaceaem Lantaneae) in South America. Ann Mo Bot Gard 101:568–609

    Article  Google Scholar 

  • Oliva M, Will I, Ordoñez L, García Ovando H, Demo YM. (2001). Estudio comparativo del efecto antimicrobiano de extractos crudos vegetales y quinolonas. Abstract P-115. X° Simposio Latinoamericano de Farmacobotánica. 8-11de abril de 2001. Comodoro Rivadavia, Chubut

    Google Scholar 

  • Oliveira de Souza PO, Bianchi SE, Figueró F, Heimfarth L, Moresco KS, Mayer Goncalves R, Bender Hoppe J, Peres Klein C, Gazzana Salbego C, Pens Gelains D, Link Bassani V, Zanotto Gilho A, Fonseca Moreira JC (2018) Anticancer activity of flavonoids isolated from Achyrocline satureioides in gliomas cell lines. Toxicol In Vitro 51:23–33

    Article  CAS  Google Scholar 

  • Palacios SM, Bertoni A, Rossi Y, Santander R, Urzúa A (2009) Insecticidal activity of essential oils from native medicinal plants of Central Argentina against the housefly, Musca domestica (L.). Parasitol Res 106(1):207–212

    Article  PubMed  Google Scholar 

  • Pascual ME, Slowing K, Carretero E, Sánchez Mata D, Villar A (2001) Lippia: traditional uses, chemistry and pharmacology: a review. J Ethnopharmacol 76:201–214

    Article  CAS  PubMed  Google Scholar 

  • Pedemonte M, Rivera F, Testa M, Velluti R, Dajas F, Nadruz E (2013) Achyrocline satureioides (LAM) D.C. would improve sleep quality in patients with Obstructive Sleep Apnea Syndrome: a pilot study. Sleep Sci 6(4):135–140

    Google Scholar 

  • Pellegrini MC, Alonso-Salces RM, Umpierrez ML, Rossini C, Fuselli SR (2017) Chemical composition, antimicrobial activity and mode of action of essential oils against Paenibacillus larvae, ethiological agent of American foulbrood on Apis mellifera. Chem Biodivers 14(4) https://doi.org/10.1002/cbdv.201600382

    Article  CAS  Google Scholar 

  • Peruchi MP, Braga MEM, Meireles MAA (2005) Achyrocline satureioides (Macela) flowers extracts obtained by supercritical fluid extraction. 10th European meeting on Supercritical Fluids: Reaction, Materials and Natural Products Processing

    Google Scholar 

  • Primo V, Rovera M, Zanon S, Oliva M, Demo M, Daghero J, Sabini L (2001) Determination of the antibacterial and antiviral activity of the essential oil from Minthostachys verticillata (Griseb) Epling. Rev Argent Microbiol 33:113–117

    CAS  PubMed  Google Scholar 

  • Ragonese A, Milano V (1984) Vegetales y Sustancias Tóxicas de la Flora Argentina. En: Enciclopedia Argentina de la Agricultura y Jardinería, 2ª. Ed. Edit. Acme, Buenos Aires. pp 256–257

    Google Scholar 

  • Rahimi M (2015) A review: anti diabetic medicinal plants used for diabetes mellitus. Bull Env Pharmacol Life Sci 4(2):163–180

    Google Scholar 

  • Ratera EL, Ratera MO (1980) Plantas de la Flora Argentina empleadas en medicina popular. Ed. Hemisferio sur S.A.

    Google Scholar 

  • Retta DS (2014) Determinación de calidad de “marcela” Achyrocline satureioides (Lam.) DC. (Asteraceae). Parámetros fitoquímicos. Dominguezia 30(2):5–17

    Google Scholar 

  • Retta SD, López P, Gattuso M, Gattuso S, Ferraro G, Bandoni Al (2007) Normalización farmacopeica de marcela (Achyrocline satureioides (Lam. DC.): Validación del método de cuantificación. Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas (BLACPMA) 6(6):380–381

    Google Scholar 

  • Retta D, Dellacassa E, Villamil J, Suárez SA, Bandoni AL (2012) Marcela, a promising medicinal and aromatic plant from Latin America: a review. Ind Crop Prod 38:27–38

    Article  Google Scholar 

  • Ricciardi GAL, Van Baren CM, Lira PDL, Ricciardi AIA, Lorenzo D, Dellacasa E, Bandoni AL (2005) Volatile consitutents from aerial parts of Aloysia gratissima (Gilies and Hook) Tronc. var. gratissima growing in Corrientes, Argentina. Flavour Frag J 21:698–703

    Article  CAS  Google Scholar 

  • Rivera Megret FR, Tejera Correa D, AbinCarriquiri JA, Prunell dos Santos G, Martínez Busi M, Dajas Méndz F (2013) Achyrocline stureioides (Lam,) DC. (marcela) reduces brain damage in permanent focal ischemia in rats. Revista Cubana de Plantas Medicinales 18(3):445–460

    Google Scholar 

  • Rivera F, Urbanavicius J, Gervaz E, Morquio A, Dajas F (2004) Some aspects of the in vivo neuroprotective capacity of flavonoids: bioavailability and structure-activity relationship. Neurotox Res 6(7–8):543–553

    Article  PubMed  Google Scholar 

  • Rocha Sperotto V, Levay Murari A, Rebellato da Silva DA, Rubert Possenti CG, Wiest JM, Marchionatti Avancini CA (2012) Activity of the Decoction of Achyrocline satureioides D.C. (Lam.) – Asteraceae (“macela”) against Standard and Isolated Bacteria from Bovine Mastitis. Acta Sci Vet 40(3):1052–1059

    Google Scholar 

  • Roig FA (2001) Flora medicinal mendocina, las plantas medicinales y aromáticas de la provincia de Mendoza, Argentina. Ed. EDIUNC, Mendoza

    Google Scholar 

  • Rojas de Arias A, Ferro E, Inchausti A, Ascurra M, Acosta N, Rodríguez E, Fournet A (1995) Mutagenicity, insecticidal and trypanocidal activity of some Paraguayan Asteraceae. J Ethnopharmacol 45:35–41

    Article  CAS  PubMed  Google Scholar 

  • Rotman AD, Múlgura de Romero ME (1999) Verbenaceae. Aportes Botánicos de Salta-Seria Flora 5(11):1–83

    Google Scholar 

  • Ruffa MJ, Ferraro G, Wagner ML, Calcagno ML, Campos RH, Cavallaro L (2002) Cytotoxic effect of Argentine medicinal plant extracts on human hepatocellular carcinoma cell line. J Ethnopharmacol 79:335–339

    Article  CAS  PubMed  Google Scholar 

  • Ruffinengo S, Eguaras M, Floris I, Faverin C, Bailac P, Ponzi M (2005) LD50 and repellent effects of essential oils from Argentinian wild plant species on Varroa destructor. J Econ Entomol 98:651–655

    Article  CAS  PubMed  Google Scholar 

  • Ruiz Leal A (1972) Flora popular Mendocina. Deserta 3:9–296

    Google Scholar 

  • Sabini MC, Cariddi LN, Escobar FM, Bachetti RA, Sutil SB, Contigiani MS, Zanon SM, Sabini LI (2011) Evaluation of cytogenotoxic effects of cold aqueous extract from Achyrocline satureioides by Allium cepa L test. Nat Prod Commun 6(7):995–998

    CAS  PubMed  Google Scholar 

  • Sabini MC, Cariddi LN, Escobar FM, Mañas F, Comini L, Reinoso E, Sutil SB, Acosta C, Núñez Montoya S, Contigiani MS, Zanon SM, Sabini LI (2013) Evaluation of the cytotoxicity, genotoxicity and apoptotic induction of an aqueous extract of Achyrocline satureioides (Lam.) D C. Food Chem Toxicol 60:463–470

    Article  CAS  PubMed  Google Scholar 

  • Salgueiro ACF, Folmer V, da Rosa HS, Costa MT, Boligon AA, Paula FR, Roos DH, Punetl GO (2016) In vitro and in silico antioxidant and toxicological activities of Achyrocline satureioides. J Ethnopharmacol 194:6–14

    Article  CAS  PubMed  Google Scholar 

  • Schiuma G (1997) Las plantas aromáticas y medicinales silvestres como productos primarios. Anales de Saipa 15:13–19

    Google Scholar 

  • Schmidt-Lebuhn AN (2008) Ethnobotany, biochemistry and pharmacology of Minthostachys (Lamiaceae). J Ethnopharmacol 118:343–353

    Article  CAS  PubMed  Google Scholar 

  • Sérsic A, Cocucci A, Benítez-Vieyra S, Cosacov A, Díaz L, Glinos E, Grosso N, Lazarte C, Medina M, Moré M, Moyano M, Nattero J, Paiaro V, Trujillo C, Wiemer P (2010) Flores del Centro de Argentina. Una guía ilustrada para conocer 141 especies típicas. Academia Nacional de Ciencias, Córdoba

    Google Scholar 

  • Soler E, Dellacasa E, Moyna M (1986) Composition of Aloysia gratissima flower essential oil. Planta Med 52:488–490

    Article  Google Scholar 

  • Souza AA, Wiest JM (2005) Atividade anti-bacteriana de Aloysia gratissima (Gill et Hook) Tronc. (garupá, ervasanta), usada na medicina tradicional no Rio Gran-de do Sul – Brasil. Rev Bras Pl Med Botucatu 9(3):23–29

    Google Scholar 

  • Speroni E, Cervellati R, Govoni P, Guizzardi S, Renzulli C, Guerra M (2003) Efficacy of different Cynara scolymus preparations on liver complaints. J Ethnopharmacol 86:203–211

    Article  CAS  PubMed  Google Scholar 

  • Strasser B, Fernández EA (2006) Tomillo del campo (Acantholippia seriphioides (A. Gray) Mold.). En: Cultivemos plantas nativas. Ed. Universidad Nacional de San Luis, San Luis

    Google Scholar 

  • Strasser B, Fernández EA, Bandoni AL, Juárez MA, Elechosa MA (2002) Estudios para la conservación de una población de Acantholippia seriphioides (A. Gray) Mold. en San Luis y de las variaciones en lacomposición de su aceite esencial. Communication to the I Congreso Latinoamericano de Fitoquímica y IV Reunión de la Sociedad Latinoamericana de Fitoquímica, Buenos Aires

    Google Scholar 

  • Terblanché FC, Kornelius G (1996) Essential oil constituents of the genus Lippia (Verbenaceae)-A Literature review. J Essent Oil Res 8:471–485

    Article  Google Scholar 

  • Toursarkissian M (1980) Plantas Medicinales de la Argentina. Sus nombres botánicos, vulgares, usos y distribución geográfica. Editorial hemisferio sur

    Google Scholar 

  • Trovati G, Sanchez EA, Chierice GO (2009) TLC Separation and Identification of the Essential Oil Constituents from Aloysia gratissima. J Liq Chromatogr Relat Technol 32:890–895

    Article  CAS  Google Scholar 

  • Valladares GR, Zapata A, Zygadlo J, Banchio E (2002) Phytochemical induction by herbivores could affect quality of essential oils from aromatic plants. J Agric Food Chem 50(14):4059–4061

    Article  CAS  PubMed  Google Scholar 

  • Van Baren CM, Di Leo LP, Elechosa MA, Molina AM, Juarez MA, Martínez A, Perelman S, Bandoni AL (2014) New insights into the chemical biodiversity of Minthostachys mollis in Argentina. Biochem Syst Ecol 57:374–383

    Article  CAS  Google Scholar 

  • Van Baren C, Elechosa MA, Di Leo LP, Retta DS, Juárez MA, Martínez AJ, Molina AM, Bandoni AL (2015) Acantholippia seriphioides: Chemical biodi-versity of wild populations from the Cuyo region in Argentina. Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas 14(1):33–41

    Google Scholar 

  • Vogt MV, Sutil SB, Escobar FM, Sabibi MC, Cariddi LN, Torres CV, Zanon SM, Sabini LI (2010a) Minthostachys verticillata essentials oil and its major components: antiherpeticselective action in HEp-2 cells. Mol Med Chem 21:117–120

    Google Scholar 

  • Vogt V, Tonn C, Sabini L, Rosas S (2010b) Fungitoxic effects of Achyrocline satureioides (marcela) on plant pathogens. Mol Med Chem 21:109–112

    Google Scholar 

  • Zeni ALB, Vandresen-Filho S, Dal-Cim T, Martins WC, Bertoldo DB, Maraschin M, Tasca CI (2014) Aloysia gratissima prevents cellular damage induced by glutamatergic excitotoxicity. J Pharm Pharmacol 66(9):1294–1302

    Article  CAS  PubMed  Google Scholar 

  • Zorzi GK, Caregnato F, Fonseca Moreira JC, Ferreira Teixeira H, Santana Carvalho EL (2015) Antioxidant Effect of Nanoemulsions Containing Extract of Achyrocline satureioides (Lam) D.C.—Asteraceae. AAPS Pharm Sci Tech 17(4). https://doi.org/10.1208/s12249-015-0408-8

    Article  CAS  PubMed  Google Scholar 

  • Zuloaga FO, Morrone ON, Belgrano MJ, Marticorena C, Marchesi E (eds) (2008) Catálogo de las plantas vasculares del Cono Sur. Monogr. Syst Bot Missouri Bot Gard 107(1–3):i–xcvi, 1–3348

    Google Scholar 

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Alvarez, M.A. (2019). Cuyo. In: Pharmacological Properties of Native Plants from Argentina. Springer, Cham. https://doi.org/10.1007/978-3-030-20198-2_3

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