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Scientific Basis for Stem Cell Therapy

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Deer's Treatment of Pain

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Abstract

Stem cells have a proven record of safety and efficacy over the past 50 years of research. Regenerative therapy continues to be an extremely active field of basic science and translational research with significant promise in treatment of previously untreatable pathophysiology. The fast development in epigenetics, genetic engineering technologies, and 3D printing is opening new frontiers in advancing the utility of stem cells, and minimally invasive technology provides a platform for clinical application with promising results. This chapter outlines the basic characterizations of stem cells, reviews their history and supporting evidence, and explores some of the clinical applications currently under investigation.

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Authors and Affiliations

  1. Department of Anesthesiology, Mayo Clinic, Rochester, MN, USA

    Luke A. Law

  2. Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, USA

    Christine L. Hunt

  3. Department of Physical Medicine and Rehabilitation, Division of Pain Medicine, Spine Center, Mayo Clinic, Rochester, MN, USA

    Wenchun Qu

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  1. Luke A. Law
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  2. Christine L. Hunt
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  3. Wenchun Qu
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Correspondence to Wenchun Qu .

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Editors and Affiliations

  1. The Spine and Nerve Center of the Virginias, Charleston, WV, USA

    Timothy R. Deer

  2. Evolve Restorative Center, Santa Rosa, CA, USA

    Jason E. Pope

  3. Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, USA

    Tim J. Lamer

  4. Pain Diagnostics and Interventional Care, Sewickley, PA, USA

    David Provenzano

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Law, L.A., Hunt, C.L., Qu, W. (2019). Scientific Basis for Stem Cell Therapy. In: Deer, T., Pope, J., Lamer, T., Provenzano, D. (eds) Deer's Treatment of Pain. Springer, Cham. https://doi.org/10.1007/978-3-030-12281-2_88

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