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Multiplex Immunoassays

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Point-of-Care Technologies Enabling Next-Generation Healthcare Monitoring and Management

Abstract

Multiplex immunoassays (IAs) refer to IA formats that can simultaneously determine many analytes in a single sample. They are becoming critically important in healthcare for the diagnosis of complex diseases, which require the simultaneous monitoring of multiple disease biomarkers. The ongoing research efforts are based on the determination of clinical scores for such complex diseases by assigning appropriate weightages to various biomarkers based on their contribution to the disease. Although a wide range of multiplex IA formats have been demonstrated by researchers with few of them commercialized successfully, there is still a need for the development of advanced and bioanalytically superior multiplex IA formats that are clinically and commercially viable. Further, the multiplex IAs should align well with the established and clinically accredited IAs. We provide here an overview of various multiplex IA formats and technologies together with the challenges involved, prospects, and guided insights.

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  1. Labsystems Diagnostics Oy, Vantaa, Finland

    Sandeep Kumar Vashist

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Vashist, S.K. (2019). Multiplex Immunoassays. In: Point-of-Care Technologies Enabling Next-Generation Healthcare Monitoring and Management. Springer, Cham. https://doi.org/10.1007/978-3-030-11416-9_7

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  • DOI: https://doi.org/10.1007/978-3-030-11416-9_7

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