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Laboratory diagnosis of fetal toxoplasmosis

  • Conference paper
Congenital toxoplasmosis

Abstract

Since 1985, prenatal diagnosis of congenital toxoplasmosis can be reliably performed in women with suspected or confirmed Toxoplasma infection acquired during pregnancy[1]. Availability of this recent diagnostic procedure has profoundly changed the management of congenital infection before birth and more specifically algorithms of decisions regarding prenatal treatment or medical terminations of pregnancy which were previously based mostly on the sole basis of maternal infection. Therefore, termination of pregnancy for maternal infection with Toxoplasma gondii has now become unusual thanks to prenatal diagnosis along with the possibility to treat infected fetus in utero via mother with the combination regimen of pyrimethamine (PYR) and sulfadiazine (SDZ)[2]. These major advances in the field of diagnosis and therapy has allowed to shift indications of medical termination of pregnancy for toxoplasmosis almost exclusively for cases with severe lesions detected by ultrasonography.

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Authors
  1. S. Romand
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  2. P. Thulliez
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Editor information

Editors and Affiliations

  1. Faculté de Médecine de Grenoble, Université Joseph Fourier, Grenoble, France

    Pierre Ambroise-Thomas

  2. Statenserum Institut, Copenhagen, Denmark

    Peter Eskild Petersen

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© 2000 Springer-Verlag France

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Romand, S., Thulliez, P. (2000). Laboratory diagnosis of fetal toxoplasmosis. In: Ambroise-Thomas, P., Petersen, P.E. (eds) Congenital toxoplasmosis. Springer, Paris. https://doi.org/10.1007/978-2-8178-0847-5_10

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  • DOI: https://doi.org/10.1007/978-2-8178-0847-5_10

  • Publisher Name: Springer, Paris

  • Print ISBN: 978-2-287-59664-3

  • Online ISBN: 978-2-8178-0847-5

  • eBook Packages: Springer Book Archive

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