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Proteomics of Human Bile

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Proteomics of Human Body Fluids

Abstract

Bile is an important body fluid with crucial functions ranging from fat absorption to excretion of metabolic breakdown products. Although the chemical composition of human bile is well understood, its protein constituents are beginning to be unravelled only recently. Here, we provide an overview of the proteomics of human bile, both in health and in diseases such as cholangiocarcinoma. A comprehensive catalog of proteins in the bile should facilitate better understanding of its role in physiology and the development and validation of biomarkers for hepatobiliary disorders.

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Author information

Authors and Affiliations

  1. McKusick-Nathans Institute of Genetic Medicine and Department of Biological Chemistry, Johns Hopkins University, Baltimore, MD

    Troels Zakarias Kristiansen

  2. Department of Biochemistry and Molecular Biology, University of Southern Denmark, Campusvej 55, Odense M, Denmark

    Troels Zakarias Kristiansen

  3. McKusick-Nathans Institute of Genetic Medicine, The Sol Goldman Pancreatic Cancer Research Center, and Departments of Biological Chemistry, Pathology and Oncology, Johns Hopkins University, Baltimore, MD

    Anirban Maitra

  4. McKusick-Nathans Institute of Genetic Medicine, and Departments of Biological Chemistry, Oncology and Pathology, Johns Hopkins University, Baltimore, MD

    Akhilesh Pandey

Authors
  1. Troels Zakarias Kristiansen
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  2. Anirban Maitra
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  3. Akhilesh Pandey
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Editor information

Editors and Affiliations

  1. Medical Molecular Biology Unit Office for Research and Development Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

    Visith Thongboonkerd MD, FRCPT

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© 2007 Humana Press Inc., Totowa, NJ

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Kristiansen, T.Z., Maitra, A., Pandey, A. (2007). Proteomics of Human Bile. In: Thongboonkerd, V. (eds) Proteomics of Human Body Fluids. Humana Press. https://doi.org/10.1007/978-1-59745-432-2_18

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