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Animal Models of Cerebral Ischemia

Neurodegeneration and Cell Transplantation

  • Chapter
Cell Transplantation for Neurological Disorders

Part of the book series: Contemporary Neuroscience ((CNEURO))

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Abstract

Stroke remains a leading cause of death in the US, killing more than two of every five Americans (1). There are 500,000 cases of stroke each year, of which 400,000 are ischemic (2). Approximately 20% of the people who suffer a stroke die in the first week. However, more than 70% of stroke patients survive long term. There were an estimated 2,920,000 stroke survivors in 1988 (1). The economic cost of cerebrovascular disease in 1993 was estimated to be $117.4 billion, including costs of physician, nursing, hospital and nursing home services, medications, and lost productivity (3). Many patients, as well as their families, are devastated, since patients are often severely incapacitated with physical and mental disabilities. This health problem will continue to increase as the population of the US ages. It is important to rehabilitate stroke patients, so that they are as independent as possible with activities of daily living (2).

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Authors
  1. Cesario V. Borlongan
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  2. Toru Shimizu
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  3. John Q. Trojanowski
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  4. Shigeru Watanabe
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  5. Virginia M.-Y. Lee
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  6. Yasuo Tajima
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  7. Thomas B. Freeman
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  8. Hitoo Nishino
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  9. Paul R. Sanberg
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Editor information

Editors and Affiliations

  1. Division of Neurosurgery, Department of Pharmacology and Experimental Therapeutics, The Neuroscience Program, University of South Florida, Tampa, FL, USA

    Thomas B. Freeman MD

  2. Departments of Clinical Neurosciences and Physiology and Neuroscience, Wallenberg Neuroscience Center, Lund University, Lund, Sweden

    Håkan Widner MD, PhD

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© 1998 Springer Science+Business Media New York

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Borlongan, C.V. et al. (1998). Animal Models of Cerebral Ischemia. In: Freeman, T.B., Widner, H. (eds) Cell Transplantation for Neurological Disorders. Contemporary Neuroscience. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-476-4_11

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  • DOI: https://doi.org/10.1007/978-1-59259-476-4_11

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61737-043-4

  • Online ISBN: 978-1-59259-476-4

  • eBook Packages: Springer Book Archive

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