Overview
- Editors:
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Thomas B. Freeman
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Division of Neurosurgery, Department of Pharmacology and Experimental Therapeutics, The Neuroscience Program, University of South Florida, Tampa, USA
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Håkan Widner
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Departments of Clinical Neurosciences and Physiology and Neuroscience, Wallenberg Neuroscience Center, Lund University, Lund, Sweden
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Table of contents (16 chapters)
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Front Matter
Pages i-xviii
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- Robert A. Hauser, C. Warren Olanow, Barry J. Snow, Thomas B. Freeman
Pages 19-30
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- Marc Peschanski, Gilles Defer, Sophie Dethy, Philippe Hantraye, Marc Levivier, Jean-Paul Nguyen et al.
Pages 31-43
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- Jeffrey H. Kordower, Rose Hanbury, Krzysztof S. Bankiewicz
Pages 51-75
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- Paul R. Sanberg, Cesario V. Borlongan, Klas Wictorin, Ole Isacson
Pages 77-93
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- O. V. Kopyov, S. Jacques, M. Kurth, L. Philpott, A. Lee, M. Patterson et al.
Pages 95-134
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- Stephen B. Dunnett, Barry J. Everitt
Pages 135-169
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- Ole Isacson, Peyman Pakzaban, Wendy R. Galpern
Pages 189-210
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- Cesario V. Borlongan, Toru Shimizu, John Q. Trojanowski, Shigeru Watanabe, Virginia M.-Y. Lee, Yasuo Tajima et al.
Pages 211-230
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- Dwaine F. Emerich, Mark D. Lindner, Joel Saydoff, Frank T. Gentile
Pages 253-286
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- Silke Thode, Heather K. Raymon, Fred H. Gage
Pages 303-331
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- Dorothy E. Vawter, Karen G. Gervais
Pages 333-338
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Back Matter
Pages 339-350
About this book
Distinguished medical researchers from around the world review novel neural reconstructive techniques that appear to be beneficial for Parkinson's disease and hold promise for treating Huntington's disease, pain, demyelinating diseases, and stroke. The contributors focus on those diseases for which clinical trials are either ongoing or likely to occur in the near future. Among the topics reviewed are results and rationale for some of the leading transplant programs for the treatment of Parkinson's disease, the use of PET scanning for patient evaluation, autopsy studies of transplant recipients, transplant immunology, fetal tissue transplantation for Huntington's disease, cellular transplantation for the treatment of pain and stroke, and transplantation of myelinating cells. A full discussion of the important ethical issues surrounding the use of fetal tissue for transplantation purposes is also included.
Reviews
"The list of contributors reads like a "who's who" in neural transplantation. . .The chapters are generally well-written, logically arranged, and overall the book is a joy to read. . .this is a truly outstanding book, very well written by the leading authorities. It provides a solid basis of knowledge and understanding in this rapidly developing field. . . Not only neuroscientists, but every neurologists, neurosurgeon, and probably many internists may find this book interesting and relevant to the future of their practice. This book should be found in every medical library."-Archives of Neurology
"The editors. . .have gathered an international panel of experts to address the preclinical foundations fro human trials. . .this is an accomplished work."-Neurology
"This book is a statement-of-the-state of the art in neurotransplantation therapy....The book is a good mix of clinical and basic scientific information and was quite enjoyable to read. It establishes that transplantation therapy will have an ever increasing role in the treatment of neurologic conditions. It points out the obstacles ahead and the challenges that must be faced in the future. It should be on every functional neurosurgeon's and neurologist's bookshelf."-Le Journal Canadien des Sciences Neurologiques
"...these chapters are excellent, and give timely perspective and rationale for the development of neurotransplantation....The chapters are well written, logically arranged, and well documented....this excellent book by experts in the field provides great insight for anyone interested in neurological disease. Some of the information in this volume has not been published, and it represents a unique resource. This is an extremely rapidly developing field, and the book will allow readers to quickly understand the importance and breath of the field." -Quarterly Review of Biology
Editors and Affiliations
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Division of Neurosurgery, Department of Pharmacology and Experimental Therapeutics, The Neuroscience Program, University of South Florida, Tampa, USA
Thomas B. Freeman
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Departments of Clinical Neurosciences and Physiology and Neuroscience, Wallenberg Neuroscience Center, Lund University, Lund, Sweden
Håkan Widner
