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Hematopoietic Stem Cell Transplantation

A Historical Perspective

  • Chapter
Allogeneic Stem Cell Transplantation

Part of the book series: Current Clinical Oncology ((CCO))

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Abstract

Over the last half-century, hematopoietic cell transplantation has evolved from an idea to a well-established therapy used in the treatment of tens of thousands of individuals annually. This evolution is the product of laboratory-based investigations, studies using animal models, and especially clinical trials involving human subjects. The following brief account highlights some of the more outstanding contributions, with particular emphasis on those made during the earlier development of the procedure (Table 1). In this brief recounting it is possible to include only a small fraction of the valuable contributions, and apologies are prospectively offered to all of those whose important work is not mentioned. For a more complete retelling of the story, with more extensive bibliographies, the reader is referred to a number of other excellent papers (1–4).

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Authors
  1. Frederick R. Appelbaum MD
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Editor information

Editors and Affiliations

  1. Allogeneic Transplant Program, Ireland Cancer Center, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH, USA

    Mary J. Laughlin MD

  2. Blood and Marrow Transplant Program, Ireland Cancer Center, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH, USA

    Hillard M. Lazarus MD

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Appelbaum, F.R. (2003). Hematopoietic Stem Cell Transplantation. In: Laughlin, M.J., Lazarus, H.M. (eds) Allogeneic Stem Cell Transplantation. Current Clinical Oncology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-333-0_1

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  • DOI: https://doi.org/10.1007/978-1-59259-333-0_1

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4757-4481-1

  • Online ISBN: 978-1-59259-333-0

  • eBook Packages: Springer Book Archive

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