Allogeneic Stem Cell Transplantation

Clinical Research and Practice

  • Mary J. Laughlin
  • Hillard M. Lazarus

Part of the Current Clinical Oncology book series (CCO)

Table of contents

  1. Front Matter
    Pages i-x
  2. Historical Perspective

    1. Front Matter
      Pages 1-1
    2. Frederick R. Appelbaum
      Pages 3-9
  3. Disease Indications: Allogeneic Transplantation

    1. Front Matter
      Pages 11-11
    2. Edward Copelan
      Pages 47-56
    3. Abby B. Siegel, Linda T. Vahdat
      Pages 57-68
    4. Stefano Tarantolo, Philip J. Bierman
      Pages 69-81
    5. Igor Espinoza-Delgado, Dan L. Longo
      Pages 83-99
  4. Allogeneic Graft Selection

    1. Front Matter
      Pages 101-101
    2. Daniel Anderson, Daniel Weisdorf
      Pages 103-115
    3. Hillard M. Lazarus, Jacob M. Rowe
      Pages 117-128
    4. Juliet Barker, John E. Wagner
      Pages 129-150
    5. Omer N. Koç, Stanton L. Gerson
      Pages 151-158
    6. Ravi Vij, Randy Brown, John F. DiPersio
      Pages 159-168
    7. David A. Rizzieri, Nelson J. Chao
      Pages 169-188
  5. Supportive Care in Allogeneic Transplantation

    1. Front Matter
      Pages 189-189

About this book

Introduction

Allogeneic transplantation has dramatically grown in importance as a curative cellular therapy for patients with hematologic malignancies and selected solid tumors, marrow failure disorders, and inherited metabolic diseases. In Allogeneic Stem Cell Transplantation: Clinical Research and Practice, internationally recognized physicians and researchers review both the basics of allogeneic stem cell transplantation and recent advances in the field, particularly as they relate to antitumor effects and graft-vs-host disease. They also provide unique decision-tree analyses to guide clinicians in selecting and managing their allogeneic transplant patients. The innovations discussed cover a variety of areas, ranging from stem cell mobilization in normal donors, to indications for allogeneic transplantation other than hematologic malignancies, to the use of non-myeloablative conditioning regimens. The authors also explore new developments in the optimal selection of unrelated allogeneic grafts (e.g., matched unrelated donor, partially mismatched family member, or umbilical cord blood), the use allogeneic peripheral blood stem cell vs marrow-derived grafts for transplantation, and the kinetics of immune reconstitution after transplantation.
Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice offers both clinicians and researchers concise advice on today's best clinical practice, as well as insightful analysis of the promising new lines of laboratory research that are leading to safer and more effective allogeneic transplant procedures.

Keywords

Grading T cell blood cell cytokines hematopoietic stem cell hematopoietic stem cell transplantation immunotherapy leukemia lymphoma prevention stem cell stem cell transplantation stem cells transplantation

Editors and affiliations

  • Mary J. Laughlin
    • 1
  • Hillard M. Lazarus
    • 2
  1. 1.Allogeneic Transplant Program, Ireland Cancer Center, University Hospitals of ClevelandCase Western Reserve UniversityClevelandUSA
  2. 2.Blood and Marrow Transplant Program, Ireland Cancer Center, University Hospitals of ClevelandCase Western Reserve UniversityClevelandUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-59259-333-0
  • Copyright Information Humana Press 2003
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4757-4481-1
  • Online ISBN 978-1-59259-333-0
  • About this book