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Cyclic Nucleotide Phosphodiesterases

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Principles of Molecular Regulation

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Abstract

In multicellular organisms, cell functions are integrated through a large network of signals and homeostatic mechanisms that control the intracellular concentration of second messengers. This is a feature indispensable for the basal functions of the body, as well as for an efficient response to the continuous changes in the environment to which the organism is exposed. In addition to regulation of second messenger production, complex regulations of second messenger inactivation are also necessary to maintain cell homeostasis and to control cell sensitivity to extracellular cues.

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Authors
  1. Marco Conti
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Editors and Affiliations

  1. Oregon Regional Primate Research Center, Beaverton, and Oregon Health Sciences University, Portland, OR, USA

    P. Michael Conn PhD

  2. Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, USA

    Anthony R. Means PhD

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Conti, M. (2000). Cyclic Nucleotide Phosphodiesterases. In: Conn, P.M., Means, A.R. (eds) Principles of Molecular Regulation. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-032-2_15

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  • DOI: https://doi.org/10.1007/978-1-59259-032-2_15

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61737-104-2

  • Online ISBN: 978-1-59259-032-2

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