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New Valves: Where Do We Stand?

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Technological Advances in Surgery, Trauma and Critical Care

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Abstract

The development of “Transcatheter Aortic Valve Replacement (TAVR)” dramatically changes the field of cardiovascular medicine. The basic principle of TAVR is the percutaneous implantation of a transcatheter heart valve (THV), a bioprosthesis, which is attached to the tip of the catheter, positioned in the native aortic valve and expanded. Alain Cribier implanted in 2002 the first THV successfully. Several multicenter studies later confirmed the technical feasibility. However, its true value as an important therapeutic alternative to open heart surgery (SAVR) in inoperable and high-risk patients was confirmed by the prospective, randomized PARTNER trial. Decisive for the future acceptance of the procedure and for a possible expansion of the indication spectrum will be (1) continuous further development of the implantation technique and the prosthesis design, (2) reduction of TAVR-associated complications, (3) confirmation of the initial positive long-term results, (4) confirmation of the promising results in the treatment of surgical prosthesis dysfunctions and of patients with low to intermediate risk, and (5) reduction of implantation costs.

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References

  1. Moulopoulos SD, Anthopoulos L, Stamatelopoulos S, Stefadouros M. Catheter-mounted aortic valves. Ann Thorac Surg. 1971;11:423–30.

    Article  CAS  PubMed  Google Scholar 

  2. Paniagua D, Condado JA, Besso J, Velez M, Burger B, Bibbo S, Cedeno D, Acquatella H, Mejia C, Induni E, Fish RD. First human case of retrograde transcatheter implantation of an aortic valve prosthesis. Tex Heart Inst J. 2005;32:393–8.

    PubMed Central  PubMed  Google Scholar 

  3. Davies H. Catheter mounted valve for temporary relief of aortic insufficiency. Lancet. 1965;1.

    Google Scholar 

  4. Andersen HR, Knudsen LL, Hasenkam JM. Transluminal implantation of artificial heart valves. Description of a new expandable aortic valve and initial results with implantation by catheter technique in closed chest pigs. Eur Heart J. 1992;13:704–8.

    CAS  PubMed  Google Scholar 

  5. Bonhoeffer P, Boudjemline Y, Saliba Z, Merckx J, Aggoun Y, Bonnet D, Acar P, Le Bidois J, Sidi D, Kachaner J. Percutaneous replacement of pulmonary valve in a right-ventricle to pulmonary-artery prosthetic conduit with valve dysfunction. Lancet. 2000;356:1403–5.

    Article  CAS  PubMed  Google Scholar 

  6. Cribier A, Eltchaninoff H, Bash A, Borenstein N, Tron C, Bauer F, Derumeaux G, Anselme F, Laborde F, Leon MB. Percutaneous transcatheter implantation of an aortic valve prosthesis for calcific aortic stenosis: first human case description. Circulation. 2002;106:3006–8.

    Article  PubMed  Google Scholar 

  7. Leon MB, Smith CR, Mack M, Miller DC, Moses JW, Svensson LG, Tuzcu EM, Webb JG, Fontana GP, Makkar RR, Brown DL, Block PC, Guyton RA, Pichard AD, Bavaria JE, Herrmann HC, Douglas PS, Petersen JL, Akin JJ, Anderson WN, Wang D, Pocock S. Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery. N Engl J Med. 2010;363:1597–607.

    Article  CAS  PubMed  Google Scholar 

  8. Eltchaninoff H, Prat A, Gilard M, Leguerrier A, Blanchard D, Fournial G, Iung B, Donzeau-Gouge P, Tribouilloy C, Debrux JL, Pavie A, Gueret P. Transcatheter aortic valve implantation: early results of the FRANCE (French Aortic National CoreValve and Edwards) registry. Eur Heart J. 2011;32(2):191–7.

    Article  PubMed  Google Scholar 

  9. Thomas M, Schymik G, Walther T, Himbert D, Lefevre T, Treede H, Eggebrecht H, Rubino P, Michev I, Lange R, Anderson WN, Wendler O. Thirty-day results of the SAPIEN aortic Bioprosthesis European Outcome (source) Registry: a European registry of transcatheter aortic valve implantation using the Edwards SAPIEN valve. Circulation. 2010;122:62–9.

    Article  PubMed  Google Scholar 

  10. Vahanian A, Baumgartner H, Bax J, Butchart E, Dion R, Filippatos G, Flachskampf F, Hall R, Iung B, Kasprzak J, Nataf P, Tornos P, Torracca L, Wenink A. Guidelines on the management of valvular heart disease: the task force on the management of valvular heart disease of the European Society of Cardiology. Eur Heart J. 2007;28:230–68.

    PubMed  Google Scholar 

  11. Smid M, Ferda J, Baxa J, Cech J, Hajek T, Kreuzberg B, Rokyta R. Aortic annulus and ascending aorta: comparison of preoperative and perioperative measurement in patients with aortic stenosis. Eur J Radiol. 2010;74:152–5.

    Article  PubMed  Google Scholar 

  12. Ng AC, Delgado V, van der Kley F, Shanks M, van de Veire NR, Bertini M, Nucifora G, van Bommel RJ, Tops LF, de Weger A, Tavrlla G, de Roos A, Kroft LJ, Leung DY, Schuijf J, Schalij MJ, Bax JJ. Comparison of aortic root dimensions and geometries before and after transcatheter aortic valve implantation by 2- and 3-dimensional transesophageal echocardiography and multislice computed tomography. Circ Cardiovasc Imaging. 2010;3:94–102.

    Article  PubMed  Google Scholar 

  13. Blanke P, Siepe M, Reinohl J, Zehender M, Beyersdorf F, Schlensak C, Langer M, Pache G. Assessment of aortic annulus dimensions for Edwards SAPIEN Transapical Heart Valve implantation by computed tomography: calculating average diameter using a virtual ring method. Eur J Cardiothorac Surg. 2010;38(6):750–8.

    Article  PubMed  Google Scholar 

  14. Vahanian A, Alfieri OR, Al-Attar N, Antunes MJ, Bax J, Cormier B, Cribier A, De Jaegere P, Fournial G, Kappetein AP, Kovac J, Ludgate S, Maisano F, Moat N, Mohr FW, Nataf P, Pierard L, Pomar JL, Schofer J, Tornos P, Tuzcu M, van Hout B, von Segesser LK, Walther T. Transcatheter valve implantation for patients with aortic stenosis: a position statement from the European association of cardio-thoracic surgery (eacts) and the European society of cardiology (esc), in collaboration with the European association of percutaneous cardiovascular interventions (eapci). Eur J Cardiothorac Surg. 2008;34:1–8.

    Article  PubMed  Google Scholar 

  15. Delgado V, Ng AC, Shanks M, van der Kley F, Schuijf JD, van de Veire NR, Kroft L, de Roos A, Schalij MJ, Bax JJ. Transcatheter aortic valve implantation: role of multimodality cardiac imaging. Expert Rev Cardiovasc Ther. 2010;8:113–23.

    Article  PubMed  Google Scholar 

  16. Webb JG, Chandavimol M, Thompson CR, Ricci DR, Carere RG, Munt BI, Buller CE, Pasupati S, Lichtenstein S. Percutaneous aortic valve implantation retrograde from the femoral artery. Circulation. 2006;113:842–50.

    Article  PubMed  Google Scholar 

  17. Kaleschke G, Seifarth H, Kerckhoff G, Reinecke H, Baumgartner H. Imaging decision-making for transfemoral or transapical approach of transcatheter aortic valve implantation. EuroIntervention. 2010;6(Suppl G):G20–7.

    PubMed  Google Scholar 

  18. Masson JB, Kovac J, Schuler G, Ye J, Cheung A, Kapadia S, Tuzcu ME, Kodali S, Leon MB, Webb JG. Transcatheter aortic valve implantation: review of the nature, management, and avoidance of procedural complications. JACC Cardiovasc Interv. 2009;2:811–20.

    Article  PubMed  Google Scholar 

  19. Lichtenstein SV, Cheung A, Ye J, Thompson CR, Carere RG, Pasupati S, Webb JG. Transapical transcatheter aortic valve implantation in humans: initial clinical experience. Circulation. 2006;114:591–6.

    Article  PubMed  Google Scholar 

  20. Mukherjee C, Walther T, Borger MA, Kempfert J, Schuler G, Mohr FW, Ender J. Awake transapical aortic valve implantation using thoracic epidural anesthesia. Ann Thorac Surg. 2009;88:992–4.

    Article  PubMed  Google Scholar 

  21. Petronio AS, De Carlo M, Bedogni F, Marzocchi A, Klugmann S, Maisano F, Ramondo A, Ussia GP, Ettori F, Poli A, Brambilla N, Saia F, De Marco F, Colombo A. Safety and efficacy of the subclavian approach for transcatheter aortic valve implantation with the CoreValve revalving system. Circ Cardiovasc Interv. 2010;3:359–66.

    Article  PubMed  Google Scholar 

  22. Bauernschmitt R, Schreiber C, Bleiziffer S, Ruge H, Mazzitelli D, Hutter A, Tassani P, Lange R. Transcatheter aortic valve implantation through the ascending aorta: an alternative option for no-access patients. Heart Surg Forum. 2009;12:E63–4.

    Article  PubMed  Google Scholar 

  23. Smith CR, Leon MB, Mack MJ, Miller DC, Moses JW, Svensson LG, Tuzcu EM, Webb JG, Fontana GP, Makkar RR, Williams M, Dewey T, Kapadia S, Babaliaros V, Thourani VH, Corso P, Pichard AD, Bavaria JE, Herrmann HC, Akin JJ, Anderson WN, Wang D, Pocock SJ. Transcatheter versus surgical aortic-valve replacement in high-risk patients. N Engl J Med. 2011;364:2187–98.

    Article  CAS  PubMed  Google Scholar 

  24. Kodali SK, Williams MR, Smith CR, Svensson LG, Webb JG, Makkar RR, Fontana GP, Dewey TM, Thourani VH, Pichard AD, Fischbein M, Szeto WY, Lim S, Greason KL, Teirstein PS, Malaisrie SC, Douglas PS, Hahn RT, Whisenant B, Zajarias A, Wang D, Akin JJ, Anderson WN, Leon MB. Two-year outcomes after transcatheter or surgical aortic-valve replacement. N Engl J Med. 2012;366:1686–95.

    Article  CAS  PubMed  Google Scholar 

  25. Piazza N, Grube E, Gerckens U, den Heijer P, Linke A, Luha O, Ramondo A, Ussia G, Wenaweser P, Windecker S, Laborde JC, de Jaegere P, Serruys PW. Procedural and 30-day outcomes following transcatheter aortic valve implantation using the third generation (18 fr) corevalve revalving system: results from the multicentre, expanded evaluation registry 1-year following ce mark approval. EuroIntervention. 2008;4:242–9.

    Article  PubMed  Google Scholar 

  26. Tamburino C, Capodanno D, Ramondo A, Petronio AS, Ettori F, Santoro G, Klugmann S, Bedogni F, Maisano F, Marzocchi A, Poli A, Antoniucci D, Napodano M, De Carlo M, Fiorina C, Ussia GP. Incidence and predictors of early and late mortality after transcatheter aortic valve implantation in 663 patients with severe aortic stenosis. Circulation. 2011;123:299–308.

    Article  PubMed  Google Scholar 

  27. Zahn R, Gerckens U, Grube E, Linke A, Sievert H, Eggebrecht H, Hambrecht R, Sack S, Hauptmann KE, Richardt G, Figulla HR, Senges J. Transcatheter aortic valve implantation: first results from a multi-centre real-world registry. Eur Heart J. 2011;32(2):198–204.

    Article  PubMed  Google Scholar 

  28. Moat NE, Ludman P, de Belder MA, Bridgewater B, Cunningham AD, Young CP, Thomas M, Kovac J, Spyt T, MacCarthy PA, Wendler O, Hildick-Smith D, Davies SW, Trivedi U, Blackman DJ, Levy RD, Brecker SJ, Baumbach A, Daniel T, Gray H, Mullen MJ. Long-term outcomes after transcatheter aortic valve implantation in high-risk patients with severe aortic stenosis: the U.K. TAVR (United Kingdom transcatheter aortic valve implantation) registry. J Am Coll Cardiol. 2011;58:2130–8.

    Article  PubMed  Google Scholar 

  29. Rodes-Cabau J, Webb JG, Cheung A, Ye J, Dumont E, Feindel CM, Osten M, Natarajan MK, Velianou JL, Martucci G, DeVarennes B, Chisholm R, Peterson MD, Lichtenstein SV, Nietlispach F, Doyle D, DeLarochelliere R, Teoh K, Chu V, Dancea A, Lachapelle K, Cheema A, Latter D, Horlick E. Transcatheter aortic valve implantation for the treatment of severe symptomatic aortic stenosis in patients at very high or prohibitive surgical risk: acute and late outcomes of the multicenter Canadian experience. J Am Coll Cardiol. 2010;55:1080–90.

    Article  PubMed  Google Scholar 

  30. Cribier A, Eltchaninoff H, Tron C, Bauer F, Agatiello C, Sebagh L, Bash A, Nusimovici D, Litzler PY, Bessou JP, Leon MB. Early experience with percutaneous transcatheter implantation of heart valve prosthesis for the treatment of end-stage inoperable patients with calcific aortic stenosis. J Am Coll Cardiol. 2004;43:698–703.

    Article  PubMed  Google Scholar 

  31. Webb JG, Pasupati S, Humphries K, Thompson C, Altwegg L, Moss R, Sinhal A, Carere RG, Munt B, Ricci D, Ye J, Cheung A, Lichtenstein SV. Percutaneous transarterial aortic valve replacement in selected high-risk patients with aortic stenosis. Circulation. 2007;116:755–63.

    Article  PubMed  Google Scholar 

  32. Walther T, Simon P, Dewey T, Wimmer-Greinecker G, Falk V, Kasimir MT, Doss M, Borger MA, Schuler G, Glogar D, Fehske W, Wolner E, Mohr FW, Mack M. Transapical minimally invasive aortic valve implantation: multicenter experience. Circulation. 2007;116:I240–5.

    Article  PubMed  Google Scholar 

  33. Svensson LG, Dewey T, Kapadia S, Roselli EE, Stewart A, Williams M, Anderson WN, Brown D, Leon M, Lytle B, Moses J, Mack M, Tuzcu M, Smith C. United states feasibility study of transcatheter insertion of a stented aortic valve by the left ventricular apex. Ann Thorac Surg. 2008;86:46–54. Discussion 54–45.

    Article  PubMed  Google Scholar 

  34. Walther T, Kasimir MT, Doss M, Schuler G, Simon P, Schachinger V, Mohr FW, Wimmer-Greinecker G. One-year interim follow-up results of the TRAVERCE trial: the initial feasibility study for trans-apical aortic-valve implantation. Eur J Cardiothoracic Surg. 2011;39:532–7.

    Article  Google Scholar 

  35. Rodes-Cabau J, Dumont E, De LaRochelliere R, Doyle D, Lemieux J, Bergeron S, Clavel MA, Villeneuve J, Raby K, Bertrand OF, Pibarot P. Feasibility and initial results of percutaneous aortic valve implantation including selection of the transfemoral or transapical approach in patients with severe aortic stenosis. Am J Cardiol. 2008;102:1240–6.

    Article  PubMed  Google Scholar 

  36. Lefevre T, Kappetein AP, Wolner E, Nataf P, Thomas M, Schachinger V, De Bruyne B, Eltchaninoff H, Thielmann M, Himbert D, Romano M, Serruys P, Wimmer-Greinecker G. One year follow-up of the multi-centre european partner transcatheter heart valve study. Eur Heart J. 2011;32:148–57.

    Article  PubMed Central  PubMed  Google Scholar 

  37. Grube E, Laborde JC, Zickmann B, Gerckens U, Felderhoff T, Sauren B, Bootsveld A, Buellesfeld L, Iversen S. First report on a human percutaneous transluminal implantation of a self-expanding valve prosthesis for interventional treatment of aortic valve stenosis. Catheter Cardiovasc Interv. 2005;66:465–9.

    Article  PubMed  Google Scholar 

  38. Grube E, Laborde JC, Gerckens U, Felderhoff T, Sauren B, Buellesfeld L, Mueller R, Menichelli M, Schmidt T, Zickmann B, Iversen S, Stone GW. Percutaneous implantation of the CoreValve self-expanding valve prosthesis in high-risk patients with aortic valve disease: the Siegburg first-in-man study. Circulation. 2006;114:1616–24.

    Article  PubMed  Google Scholar 

  39. Grube E, Schuler G, Buellesfeld L, Gerckens U, Linke A, Wenaweser P, Sauren B, Mohr FW, Walther T, Zickmann B, Iversen S, Felderhoff T, Cartier R, Bonan R. Percutaneous aortic valve replacement for severe aortic stenosis in high-risk patients using the second- and current third-generation self-expanding CoreValve prosthesis: device success and 30-day clinical outcome. J Am Coll Cardiol. 2007;50:69–76.

    Article  PubMed  Google Scholar 

  40. Bosmans JM, Kefer J, De Bruyne B, Herijgers P, Dubois C, Legrand V, Verheye S, Rodrigus I. Procedural, 30-day and one year outcome following CoreValve or Edwards transcatheter aortic valve implantation: results of the Belgian national registry. Interact Cardiovasc Thorac Surg. 2011;12:762–7.

    Article  PubMed  Google Scholar 

  41. Clavel MA, Webb JG, Rodes-Cabau J, Masson JB, Dumont E, De Larochelliere R, Doyle D, Bergeron S, Baumgartner H, Burwash IG, Dumesnil JG, Mundigler G, Moss R, Kempny A, Bagur R, Bergler-Klein J, Gurvitch R, Mathieu P, Pibarot P. Comparison between transcatheter and surgical prosthetic valve implantation in patients with severe aortic stenosis and reduced left ventricular ejection fraction. Circulation. 2010;122:1928–36.

    Article  CAS  PubMed  Google Scholar 

  42. Clavel MA, Webb JG, Pibarot P, Altwegg L, Dumont E, Thompson C, De Larochelliere R, Doyle D, Masson JB, Bergeron S, Bertrand OF, Rodes-Cabau J. Comparison of the hemodynamic performance of percutaneous and surgical bioprostheses for the treatment of severe aortic stenosis. J Am Coll Cardiol. 2009;53:1883–91.

    Article  PubMed  Google Scholar 

  43. Bauer F, Eltchaninoff H, Tron C, Lesault PF, Agatiello C, Nercolini D, Derumeaux G, Cribier A. Acute improvement in global and regional left ventricular systolic function after percutaneous heart valve implantation in patients with symptomatic aortic stenosis. Circulation. 2004;110:1473–6.

    Article  PubMed  Google Scholar 

  44. Bagur R, Rodes-Cabau J, Dumont E, Larochelliere RD, Doyle D, Bertrand OF, Cote M, Poirier P, Pibarot P. Exercise capacity in patients with severe symptomatic aortic stenosis before and six months after transcatheter aortic valve implantation. Am J Cardiol. 2011;108:258–64.

    Article  PubMed  Google Scholar 

  45. Reynolds MR, Magnuson EA, Lei Y, Leon MB, Smith CR, Svensson LG, Webb JG, Babaliaros VC, Bowers BS, Fearon WF, Herrmann HC, Kapadia S, Kodali SK, Makkar RR, Pichard AD, Cohen DJ. Health-related quality of life after transcatheter aortic valve replacement in inoperable patients with severe aortic stenosis. Circulation. 2011;124:1964–72.

    Article  PubMed  Google Scholar 

  46. Goncalves A, Marcos-Alberca P, Almeria C, Feltes G, Hernandez-Antolin RA, Rodriguez E, Rodrigo JL, Cobiella J, Maroto L, Cardoso JC, Macaya C, Zamorano JL. Quality of life improvement at midterm follow-up after transcatheter aortic valve implantation. Int J Cardiol. 2013;162(2):117–22.

    Article  PubMed  Google Scholar 

  47. Bagur R, Rodes-Cabau J, Dumont E, De Larochelliere R, Doyle D, Pibarot P, Cote M, Clavel MA, Villeneuve J, Gutierrez M, Poirier P, Bertrand OF. Performance-based functional assessment of patients undergoing transcatheter aortic valve implantation. Am Heart J. 2011;161:726–34.

    Article  PubMed  Google Scholar 

  48. Ussia GP, Mule M, Barbanti M, Cammalleri V, Scarabelli M, Imme S, Capodanno D, Ciriminna S, Tamburino C. Quality of life assessment after percutaneous aortic valve implantation. Eur Heart J. 2009;30:1790–6.

    Article  PubMed  Google Scholar 

  49. Gotzmann M, Pljakic A, Bojara W, Lindstaedt M, Ewers A, Germing A, Mugge A. Transcatheter aortic valve implantation in patients with severe symptomatic aortic valve stenosis-predictors of mortality and poor treatment response. Am Heart J. 2011;162:238–45.

    Article  PubMed  Google Scholar 

  50. Thomas M, Schymik G, Walther T, Himbert D, Lefevre T, Treede H, Eggebrecht H, Rubino P, Colombo A, Lange R, Schwarz RR, Wendler O. One-year outcomes of cohort 1 in the Edwards SAPIEN Aortic Bioprosthesis European Outcome (source) registry: the European registry of transcatheter aortic valve implantation using the Edwards SAPIEN valve. Circulation. 2011;124:425–33.

    Article  PubMed  Google Scholar 

  51. Gilard M, Eltchaninoff H, Iung B, Donzeau-Gouge P, Chevreul K, Fajadet J, Leprince P, Leguerrier A, Lievre M, Prat A, Teiger E, Lefevre T, Himbert D, Tchetche D, Carrie D, Albat B, Cribier A, Rioufol G, Sudre A, Blanchard D, Collet F, Dos Santos P, Meneveau N, Tirouvanziam A, Caussin C, Guyon P, Boschat J, Le Breton H, Collart F, Houel R, Delpine S, Souteyrand G, Favereau X, Ohlmann P, Doisy V, Grollier G, Gommeaux A, Claudel JP, Bourlon F, Bertrand B, Van Belle E, Laskar M. Registry of transcatheter aortic-valve implantation in high-risk patients. N Engl J Med. 2012;366:1705–15.

    Article  CAS  PubMed  Google Scholar 

  52. Makkar RR, Fontana GP, Jilaihawi H, Kapadia S, Pichard AD, Douglas PS, Thourani VH, Babaliaros VC, Webb JG, Herrmann HC, Bavaria JE, Kodali S, Brown DL, Bowers B, Dewey TM, Svensson LG, Tuzcu M, Moses JW, Williams MR, Siegel RJ, Akin JJ, Anderson WN, Pocock S, Smith CR, Leon MB. Transcatheter aortic-valve replacement for inoperable severe aortic stenosis. N Engl J Med. 2012;366:1696–704.

    Article  CAS  PubMed  Google Scholar 

  53. Buellesfeld L, Gerckens U, Schuler G, Bonan R, Kovac J, Serruys PW, Labinaz M, den Heijer P, Mullen M, Tymchak W, Windecker S, Mueller R, Grube E. 2-year follow-up of patients undergoing transcatheter aortic valve implantation using a self-expanding valve prosthesis. J Am Coll Cardiol. 2011;57:1650–7.

    Article  PubMed  Google Scholar 

  54. Gurvitch R, Wood DA, Tay EL, Leipsic J, Ye J, Lichtenstein SV, Thompson CR, Carere RG, Wijesinghe N, Nietlispach F, Boone RH, Lauck S, Cheung A, Webb JG. Transcatheter aortic valve implantation: durability of clinical and hemodynamic outcomes beyond 3 years in a large patient cohort. Circulation. 2010;122:1319–27.

    Article  CAS  PubMed  Google Scholar 

  55. Rodes-Cabau J, Webb J, Cheung A, Ye J, Dumont E, Chris F, Osten M, Natarajan M, Velianou JL, Martucci G, DeVarennes B, Thompson CR, Chisholm R, Peterson M, Lichtenstein S, Toggweiler S, Doyle D, DeLarochelli R, Dumesnil J, Teoh K, Chu V, Cheema A, Wood D, Pibarot P, Horlick E. Long-term outcomes following transcatheter aortic valve implantation: Insights on prognostic factors and valve durability from the Canadian multicenter experience. J the Am Coll Cardiol. 2012;59:E10–E10.

    Google Scholar 

  56. Alli OO, Booker JD, Lennon RJ, Greason KL, Rihal CS, Holmes Jr DR. Transcatheter aortic valve implantation: assessing the learning curve. J Am Coll Cardiol Intv. 2012;5:72–9.

    Article  Google Scholar 

  57. Nuis RJ, van Mieghem NM, van der Boon RM, van Geuns RJ, Schultz CJ, Oei FB, Galema TW, Raap GB, Koudstaal PJ, Geleijnse ML, Kappetein AP, Serruys PW, de Jaegere PP. Effect of experience on results of transcatheter aortic valve implantation using a Medtronic CoreValve system. Am J Cardiol. 2011;107:1824–9.

    Article  PubMed  Google Scholar 

  58. Leon MB, Piazza N, Nikolsky E, Blackstone EH, Cutlip DE, Kappetein AP, Krucoff MW, Mack M, Mehran R, Miller C, Morel MA, Petersen J, Popma JJ, Takkenberg JJ, Vahanian A, van Es GA, Vranckx P, Webb JG, Windecker S, Serruys PW. Standardized endpoint definitions for transcatheter aortic valve implantation clinical trials: a consensus report from the valve academic research consortium. Eur Heart J. 2011;32:205–17.

    Article  PubMed Central  PubMed  Google Scholar 

  59. Eggebrecht H, Schmermund A, Voigtlander T, Kahlert P, Erbel R, Mehta RH. Risk of stroke after transcatheter aortic valve implantation (TAVR): a meta-analysis of 10,037 published patients. EuroIntervention. 2012;8:129–38.

    Article  PubMed  Google Scholar 

  60. Kahlert P, Knipp SC, Schlamann M, Thielmann M, Al-Rashid F, Weber M, Johansson U, Wendt D, Jakob HG, Forsting M, Sack S, Erbel R, Eggebrecht H. Silent and apparent cerebral ischemia after percutaneous transfemoral aortic valve implantation: a diffusion-weighted magnetic resonance imaging study. Circulation. 2010;121:870–8.

    Article  PubMed  Google Scholar 

  61. Ghanem A, Muller A, Nahle CP, Kocurek J, Werner N, Hammerstingl C, Schild HH, Schwab JO, Mellert F, Fimmers R, Nickenig G, Thomas D. Risk and fate of cerebral embolism after transfemoral aortic valve implantation: a prospective pilot study with diffusion-weighted magnetic resonance imaging. J Am Coll Cardiol. 2010;55:1427–32.

    Article  PubMed  Google Scholar 

  62. Rodes-Cabau J, Dumont E, Boone RH, Larose E, Bagur R, Gurvitch R, Bedard F, Doyle D, De Larochelliere R, Jayasuria C, Villeneuve J, Marrero A, Cote M, Pibarot P, Webb JG. Cerebral embolism following transcatheter aortic valve implantation: comparison of transfemoral and transapical approaches. J Am Coll Cardiol. 2011;57:18–28.

    Article  PubMed  Google Scholar 

  63. Nuis RJ, Piazza N, Van Mieghem NM, Otten AM, Tzikas A, Schultz CJ, van der Boon R, van Geuns RJ, van Domburg RT, Koudstaal PJ, Kappetein AP, Serruys PW, de Jaegere PP. In-hospital complications after transcatheter aortic valve implantation revisited according to the valve academic research consortium definitions. Catheter Cardiovasc Interv. 2011;78:457–67.

    PubMed  Google Scholar 

  64. Nietlispach F, Wijesinghe N, Gurvitch R, Tay E, Carpenter JP, Burns C, Wood DA, Webb JG. An embolic deflection device for aortic valve interventions. J Am Coll Cardiol Intv. 2010;3:1133–8.

    Article  Google Scholar 

  65. Ussia GP, Scarabelli M, Mule M, Barbanti M, Sarkar K, Cammalleri V, Imme S, Aruta P, Pistritto AM, Gulino S, Deste W, Capodanno D, Tamburino C. Dual antiplatelet therapy versus aspirin alone in patients undergoing transcatheter aortic valve implantation. Am J Cardiol. 2011;108:1772–6.

    Article  CAS  PubMed  Google Scholar 

  66. Wenaweser P, Pilgrim T, Roth N, Kadner A, Stortecky S, Kalesan B, Meuli F, Bullesfeld L, Khattab AA, Huber C, Eberle B, Erdos G, Meier B, Juni P, Carrel T, Windecker S. Clinical outcome and predictors for adverse events after transcatheter aortic valve implantation with the use of different devices and access routes. Am Heart J. 2011;161:1114–24.

    Article  PubMed  Google Scholar 

  67. Hayashida K, Lefevre T, Chevalier B, Hovasse T, Romano M, Garot P, Mylotte D, Uribe J, Farge A, Donzeau-Gouge P, Bouvier E, Cormier B, Morice MC. Transfemoral aortic valve implantation new criteria to predict vascular complications. J Am Coll Cardiol Intv. 2011;4:851–8.

    Article  Google Scholar 

  68. Godino C, Maisano F, Montorfano M, Latib A, Chieffo A, Michev I, Al-Lamee R, Bande M, Mussardo M, Arioli F, Ielasi A, Cioni M, Taramasso M, Arendar I, Grimaldi A, Spagnolo P, Zangrillo A, La Canna G, Alfieri O, Colombo A. Outcomes after transcatheter aortic valve implantation with both Edwards-SAPIEN and CoreValve devices in a single center: the Milan experience. J Am Coll Cardiol Intv. 2010;3:1110–21.

    Article  Google Scholar 

  69. Moynagh AM, Scott DJ, Baumbach A, Khavandi A, Brecker SJ, Laborde JC, Brown S, Chowdhary S, Saravanan D, Crean PA, Teehan S, Hildick-Smith D, Trivedi U, Khogali SS, Bhabra MS, Roberts DH, Morgan KP, Blackman DJ. CoreValve transcatheter aortic valve implantation via the subclavian artery: comparison with the transfemoral approach. J Am Coll Cardiol. 2011;57:634–5.

    Article  PubMed  Google Scholar 

  70. Kahlert P, Al-Rashid F, Weber M, Wendt D, Heine T, Kottenberg E, Thielmann M, Kuhl H, Peters J, Jakob HG, Sack S, Erbel R, Eggebrecht H. Vascular access site complications after percutaneous transfemoral aortic valve implantation. Herz. 2009;34:398–408.

    Article  PubMed  Google Scholar 

  71. Cockburn J, de Belder A, Brooks M, Hutchinson N, Hill A, Trivedi U, Hildick-Smith D. Large calibre arterial access device closure for percutaneous aortic valve interventions: use of the Prostar system in 118 cases. Catheter Cardiovasc Interv. 2012;79:143–9.

    Article  PubMed  Google Scholar 

  72. Van Mieghem NM, Nuis RJ, Piazza N, Apostolos T, Ligthart J, Schultz C, de Jaegere PP, Serruys PW. Vascular complications with transcatheter aortic valve implantation using the 18 fr Medtronic CoreValve System: the Rotterdam experience. EuroIntervention. 2010;5:673–9.

    Article  PubMed  Google Scholar 

  73. Sharp AS, Michev I, Maisano F, Taramasso M, Godino C, Latib A, Denti P, Dorigo E, Giacomini A, Iaci G, Manca M, Ielasi A, Montorfano M, Alfieri O, Colombo A. A new technique for vascular access management in transcatheter aortic valve implantation. Catheter Cardiovasc Interv. 2010;75:784–93.

    Article  PubMed  Google Scholar 

  74. Saia F, Bordoni B, Marrozzini C, Ciuca C, Moretti C, Branzi A, Marzocchi A. Incidence, prognostic value and management of vascular complications with transfemoral transcatheter aortic valve implantation. Future Cardiol. 2011;7:321–31.

    Article  PubMed  Google Scholar 

  75. Sinhal A, Altwegg L, Pasupati S, Humphries KH, Allard M, Martin P, Cheung A, Ye J, Kerr C, Lichtenstein SV, Webb JG. Atrioventricular block after transcatheter balloon expandable aortic valve implantation. J Am Coll Cardiol Intv. 2008;1:305–9.

    Article  Google Scholar 

  76. Gutierrez M, Rodes-Cabau J, Bagur R, Doyle D, DeLarochelliere R, Bergeron S, Lemieux J, Villeneuve J, Cote M, Bertrand OF, Poirier P, Clavel MA, Pibarot P, Dumont E. Electrocardiographic changes and clinical outcomes after transapical aortic valve implantation. Am Heart J. 2009;158:302–8.

    Article  PubMed  Google Scholar 

  77. Godin M, Eltchaninoff H, Furuta A, Tron C, Anselme F, Bejar K, Sanchez-Giron C, Bauer F, Litzler PY, Bessou JP, Cribier A. Frequency of conduction disturbances after transcatheter implantation of an Edwards SAPIEN aortic valve prosthesis. Am J Cardiol. 2010;106:707–12.

    Article  PubMed  Google Scholar 

  78. Piazza N, Onuma Y, Jesserun E, Kint PP, Maugenest AM, Anderson RH, de Jaegere PP, Serruys PW. Early and persistent intraventricular conduction abnormalities and requirements for pacemaking after percutaneous replacement of the aortic valve. JACC Cardiovasc Interv. 2008;1:310–6.

    Article  PubMed  Google Scholar 

  79. Jilaihawi H, Chin D, Vasa-Nicotera M, Jeilan M, Spyt T, Ng GA, Bence J, Logtens E, Kovac J. Predictors for permanent pacemaker requirement after transcatheter aortic valve implantation with the CoreValve bioprosthesis. Am Heart J. 2009;157:860–6.

    Article  PubMed  Google Scholar 

  80. Erkapic D, Kim WK, Weber M, Mollmann H, Berkowitsch A, Zaltsberg S, Pajitnev DJ, Rixe J, Neumann T, Kuniss M, Sperzel J, Hamm CW, Pitschner HF. Electrocardiographic and further predictors for permanent pacemaker requirement after transcatheter aortic valve implantation. Europace. 2010;12:1188–90.

    Article  PubMed  Google Scholar 

  81. Nuis RJ, Van Mieghem NM, Schultz CJ, Tzikas A, Van der Boon RM, Maugenest AM, Cheng J, Piazza N, van Domburg RT, Serruys PW, de Jaegere PP. Timing and potential mechanisms of new conduction abnormalities during the implantation of the Medtronic CoreValve System in patients with aortic stenosis. Eur Heart J. 2011;32:2067–74.

    Article  PubMed  Google Scholar 

  82. Baan Jr J, Yong ZY, Koch KT, Henriques JP, Bouma BJ, Vis MM, Cocchieri R, Piek JJ, de Mol BA. Factors associated with cardiac conduction disorders and permanent pacemaker implantation after percutaneous aortic valve implantation with the CoreValve prosthesis. Am Heart J. 2010;159:497–503.

    Article  PubMed  Google Scholar 

  83. Fraccaro C, Buja G, Tarantini G, Gasparetto V, Leoni L, Razzolini R, Corrado D, Bonato R, Basso C, Thiene G, Gerosa G, Isabella G, Iliceto S, Napodano M. Incidence, predictors, and outcome of conduction disorders after transcatheter self-expandable aortic valve implantation. Am J Cardiol. 2011;107:747–54.

    Article  PubMed  Google Scholar 

  84. Grube E, Naber C, Abizaid A, Sousa E, Mendiz O, Lemos P, Kalil Filho R, Mangione J, Buellesfeld L. Feasibility of transcatheter aortic valve implantation without balloon pre-dilation: a pilot study. J Am Coll Cardiol Intv. 2011;4:751–7.

    Article  Google Scholar 

  85. John D, Buellesfeld L, Yuecel S, Mueller R, Latsios G, Beucher H, Gerckens U, Grube E. Correlation of device landing zone calcification and acute procedural success in patients undergoing transcatheter aortic valve implantations with the self-expanding CoreValve prosthesis. JACC Cardiovasc Interv. 2010;3:233–43.

    Article  PubMed  Google Scholar 

  86. Sherif MA, Abdel-Wahab M, Stocker B, Geist V, Richardt D, Tolg R, Richardt G. Anatomic and procedural predictors of paravalvular aortic regurgitation after implantation of the Medtronic CoreValve bioprosthesis. J Am Coll Cardiol. 2010;56:1623–9.

    Article  PubMed  Google Scholar 

  87. Detaint D, Lepage L, Himbert D, Brochet E, Messika-Zeitoun D, Iung B, Vahanian A. Determinants of significant paravalvular regurgitation after transcatheter aortic valve: implantation impact of device and annulus discongruence. J Am Coll Cardiol Intv. 2009;2:821–7.

    Article  Google Scholar 

  88. Abdel-Wahab M, Zahn R, Horack M, Gerckens U, Schuler G, Sievert H, Eggebrecht H, Senges J, Richardt G. Aortic regurgitation after transcatheter aortic valve implantation: incidence and early outcome. Results from the German transcatheter aortic valve interventions registry. Heart. 2011;97:899–906.

    Article  PubMed  Google Scholar 

  89. Stabile E, Sorropago G, Cioppa A, Cota L, Agrusta M, Lucchetti V, Rubino P. Acute left main obstructions following TAVR. EuroIntervention. 2010;6:100–5.

    Article  PubMed  Google Scholar 

  90. Kapadia SR, Svensson L, Tuzcu EM. Successful percutaneous management of left main trunk occlusion during percutaneous aortic valve replacement. Catheter Cardiovasc Interv. 2009;73:966–72.

    Article  PubMed  Google Scholar 

  91. Bagur R, Dumont E, Doyle D, Larose E, Lemieux J, Bergeron S, Bilodeau S, Bertrand OF, De Larochelliere R, Rodes-Cabau J. Coronary ostia stenosis after transcatheter aortic valve implantation. JACC Cardiol Interv. 2010;3:253–5.

    Article  Google Scholar 

  92. Elhmidi Y, Bleiziffer S, Piazza N, Hutter A, Opitz A, Hettich I, Kornek M, Ruge H, Brockmann G, Mazzitelli D, Lange R. Incidence and predictors of acute kidney injury in patients undergoing transcatheter aortic valve implantation. Am Heart J. 2011;161:735–9.

    Article  PubMed  Google Scholar 

  93. Van Linden A, Kempfert J, Rastan AJ, Holzhey D, Blumenstein J, Schuler G, Mohr FW, Walther T. Risk of acute kidney injury after minimally invasive transapical aortic valve implantation in 270 patients. Eur J Cardiothoracic Surg. 2011;39:835–42. Discussion 842–3.

    Article  Google Scholar 

  94. Nuis RJ, Van Mieghem NM, Tzikas A, Piazza N, Otten AM, Cheng J, van Domburg RT, Betjes M, Serruys PW, de Jaegere PP. Frequency, determinants, and prognostic effects of acute kidney injury and red blood cell transfusion in patients undergoing transcatheter aortic valve implantation. Catheter Cardiovasc Interv. 2011;77:881–9.

    Article  PubMed  Google Scholar 

  95. Sinning JM, Ghanem A, Steinhauser H, Adenauer V, Hammerstingl C, Nickenig G, Werner N. Renal function as predictor of mortality in patients after percutaneous transcatheter aortic valve implantation. J Am Coll Cardiol Intv. 2010;3:1141–9.

    Article  Google Scholar 

  96. Bagur R, Webb JG, Nietlispach F, Dumont E, De Larochelliere R, Doyle D, Masson JB, Gutierrez MJ, Clavel MA, Bertrand OF, Pibarot P, Rodes-Cabau J. Acute kidney injury following transcatheter aortic valve implantation: predictive factors, prognostic value, and comparison with surgical aortic valve replacement. Eur Heart J. 2010;31:865–74.

    Article  PubMed Central  PubMed  Google Scholar 

  97. Webb JG, Wood DA, Ye J, Gurvitch R, Masson JB, Rodes-Cabau J, Osten M, Horlick E, Wendler O, Dumont E, Carere RG, Wijesinghe N, Nietlispach F, Johnson M, Thompson CR, Moss R, Leipsic J, Munt B, Lichtenstein SV, Cheung A. Transcatheter valve-in-valve implantation for failed bioprosthetic heart valves. Circulation. 2010;121:1848–57.

    Article  PubMed  Google Scholar 

  98. Pasic M, Unbehaun A, Dreysse S, Buz S, Drews T, Kukucka M, Hetzer R. Transapical aortic valve implantation after previous aortic valve replacement: clinical proof of the “valve-in-valve” concept. J Thorac Cardiovasc Surg. 2011;142:270–7.

    Article  PubMed  Google Scholar 

  99. Kempfert J, Van Linden A, Linke A, Borger MA, Rastan A, Mukherjee C, Ender J, Schuler G, Mohr FW, Walther T. Transapical off-pump valve-in-valve implantation in patients with degenerated aortic xenografts. Ann Thorac Surg. 2010;89:1934–41.

    Article  PubMed  Google Scholar 

Bibliography

  • Baumgartner H. Hemodynamic assessment of aortic stenosis: are there still lessons to learn? J Am Coll Cardiol. 2006;47:138–40.

    Article  PubMed  Google Scholar 

  • Bonow RO, Carabello BA, Kanu C, de Leon AC Jr, Faxon DP, Freed MD, Gaasch WH, Lytle BW, Nishimura RA, O‘Gara PT, O‘Rourke RA, Otto CM, Shah PM, Shanewise JS, Smith SC Jr, Jacobs AK, Adams CD, Anderson JL, Antman EM, Fuster V, Halperin JL, Hiratzka LF, Hunt SA, Nishimura R, Page RL, Riegel B. Acc/aha 2006 guidelines for the management of patients with valvular heart disease: a report of the american college of cardiology/american heart association task force on practice guidelines (writing committee to revise the 1998 guidelines for the management of patients with valvular heart disease): developed in collaboration with the society of cardiovascular anesthesiologists: endorsed by the society for cardiovascular angiography and interventions and the society of thoracic surgeons. Circulation 2006;114:e84–231.

    Google Scholar 

  • Buellesfeld L, Gerckens U, Grube E. Percutaneous implantation of the first repositionable aortic valve prosthesis in a patient with severe aortic stenosis. Catheter Cardiovasc Interv. 2008;71:579–84.

    Article  PubMed  Google Scholar 

  • Charlson E, Legedza AT, Hamel MB. Decision-making and outcomes in severe symptomatic aortic stenosis. J Heart Valve Dis. 2006;15:312–21.

    PubMed  Google Scholar 

  • Dewey TM, Brown DL, Herbert MA, Culica D, Smith CR, Leon MB, Svensson LG, Tuzcu M, Webb JG, Cribier A, Mack MJ. Effect of concomitant coronary artery disease on procedural and late outcomes of transcatheter aortic valve implantation. Ann Thorac Surg. 2010;89:758–67. discussion 767.

    Article  PubMed  Google Scholar 

  • Falk V, Schwammenthal EE, Kempfert J, Linke A, Schuler G, Mohr FW, Walther T. New anatomically oriented transapical aortic valve implantation. Ann Thorac Surg. 2009;87:925–6.

    Article  PubMed  Google Scholar 

  • Falk V, Walther T, Schwammenthal E, Strauch J, Aicher D, Wahlers T, Schafers J, Linke A, Mohr FW. Transapical aortic valve implantation with a self-expanding anatomically oriented valve. Eur Heart J. 2011;32:878–87.

    Article  CAS  PubMed  Google Scholar 

  • Gaia DF, Palma JH, Ferreira CB, Souza JA, Agreli G, Guilhen JC, Telis A, Buffolo E. Transapical aortic valve implantation: results of a Brazilian prosthesis. Rev Bras Cir Cardiovasc. 2010;25:293–302.

    Article  PubMed  Google Scholar 

  • Gaia DF, Palma JH, Souza JA, Guilhen JC, Telis A, Fischer CH, Ferreira CB, Buffolo E. Off-pump transapical balloon-expandable aortic valve endoprosthesis implantation. Rev Bras Cir Cardiovasc. 2009;24:233–8.

    Article  PubMed  Google Scholar 

  • Iung B, Cachier A, Baron G, Messika-Zeitoun D, Delahaye F, Tornos P, Gohlke-Barwolf C, Boersma E, Ravaud P, Vahanian A. Decision-making in elderly patients with severe aortic stenosis: why are so many denied surgery? Eur Heart J. 2005;26:2714–20.

    Article  PubMed  Google Scholar 

  • Kempfert J, Rastan AJ, Mohr FW, Walther T. A new self-expanding transcatheter aortic valve for transapical implantation—first in man implantation of the JenaValve. Eur J cardiothoracic Surg. 2011;40:761–3.

    Article  Google Scholar 

  • Kolh P, Kerzmann A, Lahaye L, Gerard P, Limet R. Cardiac surgery in octogenarians; peri-operative outcome and long-term results. Eur Heart J. 2001;22:1235–43.

    Article  CAS  PubMed  Google Scholar 

  • Latib A, Michev I, Laborde JC, Montorfano M, Colombo A. Post-implantation repositioning of the CoreValve percutaneous aortic valve. JACC Cardiovasc Interv. 2010;3:119–21.

    Article  PubMed  Google Scholar 

  • Piazza N, Nuis RJ, Tzikas A, Otten A, Onuma Y, Garcia-Garcia H, Schultz C, van Domburg R, van Es GA, van Geuns R, de Jaegere P, Serruys PW. Persistent conduction abnormalities and requirements for pacemaking six months after transcatheter aortic valve implantation. EuroIntervention. 2010;6:475–84.

    Article  PubMed  Google Scholar 

  • Rodes-Cabau J. Transcatheter aortic valve implantation: current and future approaches. Nat Rev Cardiol. 2012;9:15–29.

    Article  Google Scholar 

  • Rodes-Cabau J, Dumont E, Doyle D. “Valve-in-valve” for the treatment of paravalvular leaks following transcatheter aortic valve implantation. Catheter Cardiovasc Interv. 2009;74:1116–9.

    Article  PubMed  Google Scholar 

  • Rodes-Cabau J, Gutierrez M, Bagur R, De Larochelliere R, Doyle D, Cote M, Villeneuve J, Bertrand OF, Larose E, Manazzoni J, Pibarot P, Dumont E. Incidence, predictive factors, and prognostic value of myocardial injury following uncomplicated transcatheter aortic valve implantation. J Am Coll Cardiol. 2011;57:1988–99.

    Article  PubMed  Google Scholar 

  • Szeto WY, Augoustides JG, Desai ND, Moeller P, McGarvey ML, Walsh E, Bannan A, Herrmann HC, Bavaria JE. Cerebral embolic exposure during transfemoral and transapical transcatheter aortic valve replacement. J Card Surg. 2011;26:348–54.

    Article  PubMed  Google Scholar 

  • Tamburino C, Barbanti M, Capodanno D, Sarkar K, Cammalleri V, Scarabelli M, Mule M, Imme S, Aruta P, Ussia GP. Early- and mid-term outcomes of transcatheter aortic valve implantation in patients with logistic EuroSCORE less than 20%: a comparative analysis between different risk strata. Catheter Cardiovasc Interv. 2012;79:132–40.

    Article  PubMed  Google Scholar 

  • Taylor J. The time has come for a syntax-like trial for transcatheter aortic valve implantation. Eur Heart J. 2011;32:128–9.

    PubMed  Google Scholar 

  • Ussia GP, Barbanti M, Ramondo A, Petronio AS, Ettori F, Santoro G, Klugmann S, Bedogni F, Maisano F, Marzocchi A, Poli A, Napodano M, Tamburino C. The valve-in-valve technique for treatment of aortic bioprosthesis malposition an analysis of incidence and 1-year clinical outcomes from the Italian CoreValve registry. J Am Coll Cardiol. 2011;57:1062–8.

    Article  PubMed  Google Scholar 

  • Webb JG, Altwegg L, Boone RH, Cheung A, Ye J, Lichtenstein S, Lee M, Masson JB, Thompson C, Moss R, Carere R, Munt B, Nietlispach F, Humphries K. Transcatheter aortic valve implantation: impact on clinical and valve-related outcomes. Circulation. 2009;119:3009–16.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Cardiology and Angiology I, Heart Center of Freiburg University, Freiburg, Germany

    Jochen Reinöhl M.D., Manfred Zehender M.D. & Christoph Bode M.D.

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  1. Jochen Reinöhl M.D.
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  2. Manfred Zehender M.D.
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  1. Department of Surgery, University of Arizona, Tucson, Arizona, USA

    Rifat Latifi

  2. Department of Surgery, The University of Arizona, Tucson, Arizona, USA

    Peter Rhee

  3. Department of Surgery, Professor of Surgery, Tucson, Arizona, USA

    Rainer W.G. Gruessner

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Reinöhl, J., Zehender, M., Bode, C. (2015). New Valves: Where Do We Stand?. In: Latifi, R., Rhee, P., Gruessner, R. (eds) Technological Advances in Surgery, Trauma and Critical Care. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2671-8_27

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