Abstract
Learning events are of great interest to biologists because of their basic involvement in behavior. Up to several decades ago the major approaches to learning were of a psychological nature. In the last 20 years, however, biological approaches have achieved prominence. The earlier systematic treatments utilized neurological concepts as exemplified by Hebb’s system in 1949. Although Halstead (1951) and Katz and Halstead (1950) invoked a systematic set of chemical hypotheses and others spoke of chemical events during learning (e.g., Gerard, 1953), the chemical approach followed the neurological one.
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References
Adey, W. R., C. W. Dunlop, and C. E. Hendrix, Hippocampal slow waves. A.M.A. Arch., Neurol., 1960, 3, 74.
Agranoff, B. W., and P. D. Klinger, Puromycin effect on memory fixation in goldfish. Science, 1964, 146, 952.
Albert, D. J., Memory in mammals: evidence for a system involving nuclear ribonucleic acid. Neuropsychologia, 1966, 4, 79.
Appel, S., A critical appraisal of the role of RNA in information storage in the nervous system, in Symposium on the Role of Macromolecules in Complex Behavior, Kansas State University Publication, 1964.
Barondes, S. H., Relationship of biological regulatory mechanisms to learning and memory. Nature, 1965, 205, 18.
Barondes, S. H., and H. D. Cohen, Further studies of learning and memory after intracerebral actinomycin-D. J. Neurochem., 1966a, 13, 207.
Barondes, S. H., and H. D. Cohen, Puromycin effect on successive phases of memory storage. Science, 1966b, 151, 594.
Barondes, S. H., and M. E. Jarvik, The influences of actinomycin-D on brain RNA synthesis and on memory. J. Neurochem., 1964, 11, 187.
Batkin, S., W. T. Woodard, R. E. Cole, and J. B. Hall, RNA and actinomycin-D enhancement of learning in the carp. Psychon. Sci., 1966, 5, 345.
Bendana, F. E., and A. W. Galston, Hormone-induced stabilization of soluble RNA in pea-stem tissue. Science, 1965, 150, 69.
Bennett, E. L., M. C. Diamond, D. Krech, and M. R. Rosenzweig, Chemical and anatomical plasticity of brain. Science, 1964, 146, 610.
Bonner, J., The next new biology. Plant Sci. Bull., 1965, 11, 1.
Bonner, J., Molecular biological approaches to the study of memory, in J. Gaito, ed., Macromolecules and Behavior. New York: Appleton-Century-Crofts, Inc., 1966.
Byrne, W. L., et al. (23 authors), RNA and memory transfer. Science, 1966, 153, 658.
Corning, W. C., and E. R. John, Effect of ribonuclease on retention of conditioned response in regenerated planarians. Science, 1961, 134, 1363.
Davis, R. E., and B. W. Agranoff, Stages of memory formation in goldfish: evidence for an environmental trigger. Proc. Nat. Acad. Sci., 1966, 55, 555.
Dingman, W., and M. B. Sporn, Molecular theories of memory. Science, 1964, 144, 26.
Fjerdingstad, E. J., T. Nissen, and H. H. Roigaard-Petersen, Effect of ribonucleic acid (RNA) extracted from the brain of trained animals on learning in rats. Scand. J. Psychol., 1965, 6, 1.
Flexner, L. B., J. B. Flexner, G. de la Haba, and R. B. Roberts, Loss of memory as related to inhibition of cerebral protein synthesis. J. Neurochem., 1965, 12, 535.
Gaito, J., A biochemical approach to learning and memory. Psychol. Rev., 1961, 68, 288.
Gaito, J., Molecular Psychobiology: A Chemical Approach to Learning and Other Behavior. Springfield, Ill.: Charles C. Thomas, Publisher, 1966.
Gaito, J., J. Mottin, E. Schaeffer, J. Davison, and J. Rigler, Effects of avoidance conditioning on brain neurochemistry. Techn. Rep. MPL 4, York University, 1966.
Gerard, R. W., What is memory ? Sci. Amer., 1953, 189, 118.
Gillespie, D., and S. Spiegelman, A quantitative assay for DNA-RNA hybrids with DNA immobilized on a membrane. J. Mol. Biol., 1965, 12, 829.
Gross, C. G., and F. M. Carey, Transfer of learned response by RNA injection: failure of attempts to replicate. Science, 1965, 150, 1749.
Halstead, W. C., Brain and intelligence, in L. A. Jeffress, ed., Cerebral Mechanisms in Behavior. New York: John Wiley & Sons, Inc., 1951.
Hebb, D. O., The Organization of Behavior. New York : John Wiley & Sons, Inc., 1949.
Hyden, H., Biochemical changes in glial cells and nerve cells at varying activity, in F. Brucke, ed., Proc. 4th Intern. Congr. Biochem., III: Biochemistry of the Central Nervous System. London : Pergamon Press, 1959.
Hyden, H., Satellite cells in the nervous system. Sci. Amer., 1961, 205, 62.
Hyden, H., and E. Egyhazi, Nuclear RNA changes of nerve cells during a learning experiment in rats. Proc. Nat. Acad. Sci., 1962, 48, 1366.
Hyden, H., and P. W. Lange, A differentiation in RNA response in neurons early and late during learning. Proc. Nat. Acad. Sci., 1965, 53, 946.
Hyden, H., and P. W. Lange, A genic stimulation with production of adenine-uracil rich RNA in neurons and glia in learning. The question of transfer of RNA from glia to neurons. Die Naturwiss., 1966, 53, 64.
Jacobson, A. L., F. R. Babich, S. Bubash, and C. Goren, Maze preference in naive rats produced by injection of ribonucleic acid from trained rats. Psychon. Sci., 1966, 4, 3.
Katz, J. J., and W. C. Halstead, Protein organization and mental function. Comp. Psychol. Monogr., 1950, 20, 103.
Landauer, T. K., Two hypotheses concerning the biochemical basis of memory. Psychol. Rev., 1964, 71, 167.
Landauer, T. K., and L. Eldridge, Failure of actinomycin-D to inhibit passive avoidance learning: a confirmation. Unpublished paper, 1966.
Luttges, M., T. Johnson, C. Buck, J. Holland, and J. McGaugh, An examination of “transfer of learning” by nucleic acid. Science, 1966, 151, 834.
McConnell, J. V., RNA and memory, in Symposium on the Role of Macromolecules in Complex Behavior, Kansas State University Publication, 1964.
Meyerson, F. Z., R. I. Kruglikov, and I. A. Kolomeitseva, The role of the synthesis of nucleic acids in the mechanism of stabilization of conditioned reflexes and memory. Bull. Exp. Biol. Med., 1965, 12, 6.
Pevzner, L. Z., Nucleic acid changes during behavioral events, in J. Gaito, ed., Macromolecules and Behavior. New York : Appleton-Century-Crofts, Inc., 1966.
Plotnikoff, N., Magnesium pemoline: enhancement of learning and memory of a conditioned avoidance response. Science, 1966, 151, 703.
Pribram, K. H., Some dimensions of remembering: steps toward a neuropsychological model of memory, in J. Gaito, ed., Macromolecules and Behavior. New York: Appleton-Century-Crofts, Inc., 1966.
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Gaito, J. (1967). The Possible Role of RNA in Learning and Memory Events. In: Corning, W.C., Ratner, S.C. (eds) Chemistry of Learning. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-6565-3_4
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DOI: https://doi.org/10.1007/978-1-4899-6565-3_4
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