Abstract
The meeting that generated this book was unique in that it covered the general topic of tissue renin-angiotensin systems, and even though it concentrated on the systems in reproductive and endocrine organs, it brought together information on many other local systems. Other meetings have focussed on one or another of the tissue systems, usually in the context of blood pressure control and cardiovascular disease, but few have provided broad coverage and compared one system with another. Many topics were considered in this meeting and much information was presented. However, the meeting also made it clear that much is still to be learned. Perhaps the best way to summarize what has been done and more importantly what needs to be done in the future is to consider the tissue renin-angiotensin systems in the context of a series of questions.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Ganong WF Origin of the angiotensin II secreted by cells. Proc Soc Exp Biol Med 205: 213–219, 1994.
Dzau VJ. Vascular renin-angiotensin: A possible autocrine or paracrine system in control of vascular function. J Cardiovasc Pharmacol 6:S377–S382, 1984.
Mulrow PJ Adrenal renin: Regulation and function. Frontiers in Neuroendocrinology 13: 47–60, 1992.
Dostal DE, Rothblum KN, Conrad K.M., Cooper G.R., Baker K.M. Detection of angiotensin I and II in cultured rat cardiac myocytes and fibroblasts. Am J Physiol 263:C851–C863, 1992.
Dostal DE, Rothblum KN, Chemin MI, Cooper GR, Baker KM. Intracardiac dection of angiotensinogen and renin: A localized renin-angiotensin system in neonatal rat heart. Am J Physiol 263:C838–C850,1992.
von Lutterotti N, Catanzaro DF, Sealey JE, Laragh JH Renin is not synthesized by cardiac and extrarenal vascular tissues: A review of experimental evidenc. Circulation 89: 458–470, 1994.
Saye JA, Ragsdale V, Carey RM, Peach MJ. Localization of angiotensin peptide-forming enzymes of 3T3-F442A adipocytes. Am J Physiol 264:C1570–C1576, 1993.
Ganong WF, Deschepper CF, Steele MK, Intebi A Renin-angiotensin system in the anterior pituitary of the rat. Am J Hypertens 2: 320–322, 1989.
Deschepper CF The renin-angiotensin system in the putuitary gland. Trends Endocrinol Metab 2: 104–107, 1991.
Deschepper CF, Ganong WF Distribution of angiotensinogen immunoreactivity in rat anterior pituitary glands. Pro Soc Exp Biol Med 197: 304–309, 1991.
Sealey JE, Quimby FW, Itskovitz J, Rubattu S The ovarian renin-angiotensin system. Frontiers in Neuroendocrinology 11: 213–237, 1990.
Wilkes BM, Mento PF, Pearl AR, Hollander AM, Mossey RT, Belluci A, Bluestone PA, Mailloux LU Plasma angiotensins in anephric humans: Evidence for an extrarenal angiotensin system. J Cardiovasc Pharmacol 17: 419–423, 1991.
Sealey JE, White RP, Laragh JH, Rubin AL. Plasma renin and proprenin in anephric patients. Circ Res 41(Suppl II):17–20, 1977.
LeNoble FA, Hekking JW, Van Straaten HW, Slaaf DW, Struyker Boudier HA Angiotensin II stimulates angiogenesis in the chorio-allantoic membrane of the chick embryo. Eur J Pharmacol 195: 305–306, 1991.
Ganong WF. Reproduction and the renin-angiotensin system. Neurosci Biobehav Rev, 1995 (in press).
Ganong WF Blood, pituitary, and brain renin-angiotensin systems and regulation of secretion of anterior pituitary gland. Frontiers in Neuroendocrinology 14: 233–249, 1993.
Cushman DW, Wang FL, Fung WC, Harvey CM, DeForrest JM Differentiation of angiotensin-converting enzyme (ACE) inhibitors by their selective inhibition of ACE in physiologically important target organs. Am J Hypertens 2: 294–306, 1989.
Song K, Zhou J, Mendelsohn FAO Access of peripherally administered DuP 735 to rat brain angiotensin II receptors. Br J Pharmacol 104: 771–772, 1991.
Palmer AA, Steele MK, Shackelford RL, Ganong WF. Intravenous losartan inhibits the increase in plasma luteinizing hormone and water intake produced by intraventricular angiotensin II. Proc Soc Exp Biol Med 205:263–266; 1994.
Daud AI, Bumpus FM, Husain A. Angiotensin II: Does it have a direct obligate role in ovulation? Science 245:870–871, 1989.
Peterson CM, Zhu C, Mukaida T, Butler TA, and others The angiotensin II antagonist saralasin inhibits ovulation in the perfused rat ovary. Am J Obstet Gynecol 168: 242–245, 1993.
Kuo TC, Endo K, Dharmarajan AM, Miyazaki T, and others Direct effect of angiotensin II in in vitro perfused rabbit ovary. J Reprod Fertil 92: 469–474, 1991.
Yoshimura Y, Karube M, Koyama N, Shiokawa S, and others Angiotensin II directly induces follicle rupture and oocyte maturation in the rabbit. FEBS Lett 307: 305–308, 1992.
Yoshimura Y, Karube M, Oda T, Koyama N, Shiokawa S, Akiba M, Yoshinaga A, Nakamura Y Locally produced angiotensin II induces ovulation by stimulating prostaglandin production in in vitro perfused rabbit ovaries. Endocrinology 133: 1609–1616, 1993.
Anderson PW, D’Ablaing G, Penny R, Sherrod A, Do YS Secretion of prorenin by a virilizing ovarian tumor. Gynecol Oncol 45: 58–61, 1992.
Anderson PW, Macaulay L, Do YS, Sherrod A, D’Ablaing G, Koss M, Shinagawa T, Tran B, Montz FJ, Hsueh WA Extrarenal renin-secreting tumors: Insights into hypertension and ovarian renin production. Medicine 68: 257–268, 1989.
Palumbo A, Pourmotabbed G, Carcangiu ML, Andrade-Gordon P, Roa L, DeCherney A, Naftolin F Immunohistochemical localization of renin and angiotensin in the ovary: Comparison between normal women and patients with histologically proven polycystic ovarian disease. Fertil Steril 60: 280–284, 1993.
Ong ACM, Eisen V, Rennie DP, Homburg R, Lachelin GCL, Jacobs HS, Slater JDH The pathogenesis of the ovarian hyperstimulation syndrome (OHS): A possible role for ovarian renin. Clin Endocrinol 34: 43–49, 1990.
Salat-Baroux J, Antoine JM Accidental hyperstimulation during ovulation induction. Baillieres Clin Obstet Gynaecol 4: 627–637, 1990.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1995 Springer Science+Business Media New York
About this chapter
Cite this chapter
Ganong, W.F. (1995). Coda. In: Mukhopadhyay, A.K., Raizada, M.K. (eds) Tissue Renin-Angiotensin Systems. Advances in Experimental Medicine and Biology, vol 377. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0952-7_33
Download citation
DOI: https://doi.org/10.1007/978-1-4899-0952-7_33
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4899-0954-1
Online ISBN: 978-1-4899-0952-7
eBook Packages: Springer Book Archive