Tissue Renin-Angiotensin Systems

Current Concepts of Local Regulators in Reproductive and Endocrine Organs

  • Amal K. Mukhopadhyay
  • Mohan K. Raizada

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 377)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Frontiers in Reproductive Physiology

    1. Richard W. Steger, Andrzej Bartke
      Pages 15-32
    2. Gerhard F. Weinbauer, Eberhard Nieschlag
      Pages 55-65
    3. Kelle H. Moley, James R. Schreiber
      Pages 103-119
    4. Alex Tsafriri
      Pages 121-140
  3. Prorenin-Renin-Angiotensin System: Novel Aspects and Recent Advances

    1. Robert C. Speth, Steven M. Thompson, Susan J. Johns
      Pages 169-192
    2. Steven J. Fluharty, Lawrence P. Reagan, Daniel K. Yee
      Pages 193-215
    3. Willa A. Hsueh, Yung S. Do, Pamela W. Anderson, Ronald E. Law
      Pages 217-223
    4. G. P. Vinson
      Pages 237-251
    5. A. H. Nielsen, A. Hagemann, K. Poulsen
      Pages 253-268
    6. Amal K. Mukhopadhyay, Joana Cobilanschi, Bärbel Brunswig-Spickenheier, Freimut A. Leidenberger
      Pages 269-277
  4. Proceedings of the Symposium on Tissue Prorenin-Renin-Angiotensin Systems: Local Regulatory Actions in Reproductive and Endocrine Organs Hamburg, Germany, July 1–16, 1994

    1. Martin Paul, Philippe Stock, Matthias Langheinrich, Lutz Liefeldt, Gilbert Schönfelder, Michael Böhm
      Pages 279-283
    2. T. Voigtländer, A. Ripperger, D. Ganten, M. Bader
      Pages 285-292

About this book

Introduction

Recent progress in recombinant DNA technology and the availability of a number of nonpeptide subtype-specific receptor antagonists and of specific antibodies to components of prorenin-renin-angiotensin system (PRAS) have led to rapid advances in the under­ standing of the multifaceted role of angiotensin II, classically known as a peptide hormone of cardiovascular homeostasis. Accumulating evidence sug­ responsible for the regulation gests that, in addition to its role in salt and water metabolism, PRAS may control other physiological functions including neurosecretion, cellular proliferation, hypertrophy and/or differentiation, angiogenesis and gonadal function. At the same time, it is becoming evident that the specialized functions of endocrine glands are not only regulated by trophic hormones but also by locally produced paracrine/autocrine factors. The concept is emerging that tissue PRAS is one such locally active regulatory system. With more and more reproductive and endocrine organs being added to the list of tissues that contain a local tissue PRAS, questions are being raised by the reproductive biologists and endocrinologists as to the role of such systems in the tissues of their interest. On the other hand, the cardiovascular and renovascular physiologists are wondering about the relevance of PRAS in various peripheral tissues compared to those of the classical cardiovascular organs. It appeared, therefore, that the time was ripe for a meeting to consider a merger of interest in these two important but heretofore distinct areas of physiology.

Keywords

Angiotensin II Peptide enzymes genes pathophysiology physiology prolactin tissue

Editors and affiliations

  • Amal K. Mukhopadhyay
    • 1
  • Mohan K. Raizada
    • 2
  1. 1.Institute for Hormone and Fertility ResearchUniversity of HamburgHamburgGermany
  2. 2.University of FloridaGainesvilleUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4899-0952-7
  • Copyright Information Springer-Verlag US 1995
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4899-0954-1
  • Online ISBN 978-1-4899-0952-7
  • Series Print ISSN 0065-2598
  • About this book