Abstract
In Cl− -loaded Aplysia neurons, hyperpolarizing voltage jumps slowly activate an inward current that is carried by Cl− ions (Chesnoy-Marchais, 1982, 1983). Recent reports suggest the existence of a similar Cl− current in several other preparations. However, the more frequently studied inward currents activated by hyperpolarization are carried either by K+ ions (Hagiwara et al.,1976; Hestrin, 1981; Leech and Stanfield, 1981; Constanti and Galvan, 1983; Sakmann and Trube, 1984; Kurachi, 1985) or by both Na+ and K+ ions (Halliwell and Adams, 1982; Bader et al., 1982; Mayer and Westbrook, 1983; Bader and Bertrand, 1984; DiFrancesco, 1985, 1986; Benham et al., 1987).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Armstrong, D., and Eckert, R., 1987, Voltage-activated calcium channels that must be phosphorylated to respond to membrane depolarization, Proc. Natl. Acad. Sci. USA 84: 2518–2522.
Ascher, P., and Chesnoy-Marchais, D., 1982, Interactions between three slow potassium responses controlled by three distinct receptors in Aplysia neurones, J. Physiol. (London) 324: 67–92.
Bader, C. R., and Bertrand, D., 1984, Effect of changes in intra-and extracellular sodium on the inward (anomalous) rectification in salamander photoreceptors, J. Physiol. (London) 347: 611–631.
Bader, C. R., Bertrand, D., and Schwartz, E. A., 1982, Voltage-activated and calcium-activated currents studied in solitary rod inner segments from the salamander retina, J. Physiol. (London) 331: 253–284.
Benham, C. D., Bolton, T. B., Denbigh, J. S., and Lang, R. J., 1987, Inward rectification in freshly isolated single smooth muscle cells of the rabbit jejunum, J. Physiol. (London) 383: 461–476.
Chesnoy-Marchais, D., 1982, A Cl- conductance activated by hyperpolarization in Aplysia neurones, Nature 299: 359–361.
Chesnoy-Marchais, D., 1983, Characterization of a chloride conductance activated by hyperpolarization in Aplysia neurones, J. Physiol. (London) 342: 277–308.
Chesnoy-Marchais, D., and Evans, M. G., 1986a, Chloride channels activated by hyperpolarization in Aplysia neurones, Pfluegers Arch. 407: 694–696.
Chesnoy-Marchais, D., and Evans, M. G., 1986b, Non-selective ionic channels in Aplysia neurons, J. Membr. Biol. 93: 75–83.
Coleman, H. A., 1986, Chloride currents in Chara. A patch-clamp study, J. Membr. Biol. 93: 55–61.
Coleman, H. A., and Findlay, G. P., 1985, Ion channels in the membrane of Chara inflata, J. Membr. Biol. 83: 109–118.
Constanti, A., and Galvan, M., 1983, Fast inward-rectifying current accounts for anomalous rectification in olfactory cortex neurones, J. Physiol. (London) 385: 153–178.
DiFrancesco, D., 1985, The cardiac hyperpolarizing-activated current, it. Origins and developments, Prog. Biophys. Mol. Biol. 46: 163–183.
DiFrancesco, D., 1986, Characterization of single pacemaker channels in cardiac lino-atrial node cells, Nature 324: 470–473.
Geletyuk, V. I., and Kazachenko, V. N., 1985, Single CI- channels in molluscan neurons: Multiplicity of the conductance states, J. Membr. Biol. 86: 9–15.
Gögelein, H., Schlatter, E., and Greger, R., 1987, The “small” conductance chloride channel in the lumina) membrane of the rectal gland of the dogfish (Squalus acanthias), Pfluegers Arch. 409: 122–125.
Greger, R., Schlatter, E., and Gögelein, H., 1987, Chloride channels in the lumina] membrane of the rectal gland of the dogfish (Squalus acanthias). Properties of the “larger” conductance channel, Pfluegers Arch. 409: 114–121.
Hagiwara, S., Miyazaki, S., and Rosenthal, N. P., 1976, Potassium current and the effect of cesium on this current during anomalous rectification of the egg cell membrane of a starfish, J. Gen. Physiol. 67: 621–638.
Halliwell, J. V., and Adams, P. R., 1982, Voltage-clamp analysis of muscarinic excitation in hippocampal neurons, Brain Res. 250: 71–92.
Hestrin, S., 1981, The interaction of potassium with the activation of anomalous rectification in frog muscle membrane, J. Physiol. (London) 317: 497–508.
Kurachi, Y., 1985, Voltage-dependent activation of the inward-rectifier potassium channel in the ventricular cell membrane of guinea pig heart, J. Physiol. (London) 366: 365–385.
Leech, C. A., and Stanfield, P. R., 1981, Inward rectification in frog skeletal muscle fibres and its dependence on membrane potential and external potassium, J. Physiol. (London) 319: 295–309.
Madison, D. V., Malenka, R. C., and Nicoll, R. A., 1986, Phorbol esters block a voltage-sensitive chloride current in hippocampal pyramidal cells, Nature 321: 695–697.
Mayer, M. L., and Westbrook, G. L., 1983, A voltage clamp analysis of inward (anomalous) rectification in mouse spinal sensory ganglion neurones, J. Physiol. (London) 340: 19–43.
Miller, C., 1982, Open-state substructure of single chloride channels from Torpedo electroplax, Philos. Trans. R. Soc. London Ser. B 299: 401–411.
Miller, C., and White, M. M., 1984, Dimeric structure of single chloride channels from Torpedo electroplax, Proc. Natl. Acad. Sci. USA 81: 2772–2775.
Nowak, L., Ascher, P., and Berwald-Netter, Y., 1987, Ionic channels in mouse astrocytes in culture, J. Neurosci. 7: 101–109.
Ozeki, M., Freeman, A. R., and Grundfest, H., 1966, The membrane components of crustacean neuromuscular systems, J. Gen. Physiol. 49: 1335–1349.
Peres, A., and Bernardini, G., 1983, A hyperpolarization-activated chloride current in Xenopus laevis oocytes under voltage-clamp, Pfluegers Arch. 399: 157–159.
Reuben, J. P., Girardier, L., and Grundfest, H., 1962, The chloride permeability of crayfish muscle fibers, Biol. Bull. 123: 509–510.
Sakmann, B., and Trube, G., 1984, Conductance properties of single inwardly rectifying potassium channels in ventricular cells from guinea-pig heart, J. Physiol. (London) 347: 641–657.
Selyanko, A. A., 1984, Cd2+ suppresses a time-dependent Cl— current in rat sympathetic neurone, J. Physiol. (London) 350: 49.
Shoemaker, R. L., Frizzell, R. A., Dwyer, T. M., and Farley, J. M., 1986, Single chloride channel currents from canine tracheal epithelial cells, Biochim. Biophys. Acta 858: 235–242.
Taglietti, V., Tanzi, F., Romero, R., and Simoncini, L., 1984, Maturation involves suppression of voltage-gated currents in the frog oocyte, J. Cell. Physiol. 121: 576–588.
Tyerman, S. D., Findlay, G. P., and Paterson, G. J., 1986, Inward membrane current in Chara inflata. 1. A voltage and time-dependent Cl — component, J. Membr. Biol. 89: 139–152.
Warner, A. E., 1972, Kinetic properties of the chloride conductance of frog muscle, J. Physiol. (London) 227: 291–312.
Yamamoto, D., and Suzuki, N., 1987, Blockage of chloride channels by HEPES buffer, Proc. R. Soc. London Ser. B 230: 93–100.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1990 Springer Science+Business Media New York
About this chapter
Cite this chapter
Chesnoy-Marchais, D. (1990). Hyperpolarization-Activated Chloride Channels in Aplysia Neurons. In: Alvarez-Leefmans, F.J., Russell, J.M. (eds) Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9685-8_14
Download citation
DOI: https://doi.org/10.1007/978-1-4757-9685-8_14
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4757-9687-2
Online ISBN: 978-1-4757-9685-8
eBook Packages: Springer Book Archive