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A hyperpolarization-activated chloride current in xenopus laevis oocytes under voltage-clamp

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Abstract

Voltage-clamp experiments have been performed on ovulated Xenopus laevis oocytes. Two kinds of oocytes were studied: mature oocytes presenting the white spot due to germinal vesicle breakdown (GVBD) were found to be essentially unexcitable; oocytes without the white spot appeared to possess ionic channels which open transiently on hyperpolarization. The current is carried by chloride ions and, in Holtfreter's solution, has a reversal potential at approximately −15 mV.

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Peres, A., Bernardini, G. A hyperpolarization-activated chloride current in xenopus laevis oocytes under voltage-clamp. Pflugers Arch. 399, 157–159 (1983). https://doi.org/10.1007/BF00663914

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  • DOI: https://doi.org/10.1007/BF00663914

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