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Experimental Aminoacidemias

  • Sidney Roberts

Abstract

Abnormalities involving the human central nervous system in prenatal or early postnatal life have been described in the presence of derangements in the metabolism of several amino acids, including phenylalanine, tyrosine, branched-chain amino acids, histidine, glycine, lysine, proline, methionine, and homocystine.1–5 The roster of known amino acid dyscrasias associated with brain damage has increased almost annually over the past decade and appears to be far from complete. These diseases are generally of genetic origin. However, experimental studies suggest that environmental factors contribute to the expression of these dyscrasias and may, indeed, be responsible for their occurrence in certain cases.

Keywords

Lysosomal Enzyme Amino Acid Metabolism Maple Syrup Urine Disease Large Neutral Amino Acid Ciba Foundation Symposium 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1985

Authors and Affiliations

  • Sidney Roberts
    • 1
  1. 1.Department of Biological ChemistrySchool of Medicine, and the Brain Research Institute, UCLA Center for the Health SciencesLos AngelesUSA

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