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Polycystic Ovary Syndrome

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Principles of Diabetes Mellitus

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Abstract

Polycystic ovary syndrome (PCOS) is a common disorder affecting (depending on the population studied and the definition of the syndrome) between 5 to 20% of reproductive age women.1 If the middle of this range is considered as a realistic prevalence, then PCOS may be the most prevalent endocrine disorder in women. In spite of the widespread presence of PCOS, its precise definition still eludes both investigators and practitioners. Most consensus definitions describe PCOS as a disorder characterized by chronic anovulation and the presence of some degree of hyperandrogenism, with the exclusion of specific disorders that may lead to similar phenotypes, particularly, 21-hydroxylase deficiency and other forms of congenital adrenal hyperplasia. The definition proposed in 1990 by the National Institutes of Health Conference on PCOS requires a minimum of two criteria: menstrual abnormalities due to oligo- or anovulation, and hyperandrogenism of ovarian origin. Other disorders, such as 21-hydroxylase deficiency, androgen secreting tumors, and hyperprolactinemia, must be excluded.2

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Authors
  1. Susan B. Zweig
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  2. Marsha C. Tolentino
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  3. Leonid Poretsky
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Editors and Affiliations

  1. Division of Endocrinology, Beth Israel Medical Center, New York, New York, USA

    Leonid Poretsky M.D. (Chief, Professor of Medicine) (Chief, Professor of Medicine)

  2. Albert Einstein College of Medicine, New York, New York, USA

    Leonid Poretsky M.D. (Chief, Professor of Medicine) (Chief, Professor of Medicine)

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Zweig, S.B., Tolentino, M.C., Poretsky, L. (2004). Polycystic Ovary Syndrome. In: Poretsky, L. (eds) Principles of Diabetes Mellitus. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-6260-0_38

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