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Nonvillous Parts of the Placenta

  • Chapter
Pathology of the Human Placenta

Abstract

The nonvillous parts of the placenta include the chorionic plate, cell islands, cell columns, placental septa, basal plate, marginal zone, membranes, and fibrinoid deposits in all parts of the organ. These parts comprise one-third to one-half of the placental volume. As they are not vascularized from both the maternal and fetal circulations, they do not participate in maternofetal exchange and are clinically seemingly irrelevant structures; hence they have been largely neglected for a long time.

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References

  • Al Timimi, A., and Fox, H.: Immunohistochemical localization of follicle-stimulating hormone, luteinizing hormone, growth hormone, adrenocorticotrophic hormone and prolactin in the human placenta. Placenta 7: 163–172, 1986.

    Article  Google Scholar 

  • Al-Zuhair, A.G.H., Ibrahim, M.E.A., and Mughal, S.: Calcium deposition on the maternal surface of the human placenta: a scanning electron microscopic study. Arch. Gynecol. 234: 167–172, 1984.

    Article  PubMed  CAS  Google Scholar 

  • Andersen, J.R., Borggaard, B., Schroeder, E., Olsen, E.B., Stimpel, H., and Nyholm, H.C.: The dependence of human decidual prolactin production and secretion on the osmotic environment in vitro. Acta Endocrinol. (Copenh.) 106: 405–410, 1984.

    CAS  Google Scholar 

  • Andersen, J.R., Borggaard, B., Olsen, E.B., Stimpel, H., Nyholm, H.C., and Schroeder, E.: Effect of ouabain and bumetanide on the basal and the osmolality-affected prolactin secretion from human decidual cells in vitro. Eur. J. Obstet. Gynecol. Reprod. Biol. 23: 159–166, 1986.

    Article  PubMed  CAS  Google Scholar 

  • Andersen, J.R., Borggaard, B., Olsen, E.B, Stimpel, H., Nyholm, H.C., and Schroeder, E.: Decidual prolactin content and secretion at term: correlations with the clinical data. Acta Obstet. Gynecol. Scand. 66: 591–596, 1987.

    Article  CAS  Google Scholar 

  • Angel, E., Davis, J.R., and Nagle, R.B.: Correspondence: decidual cells. Lab. Invest. 55: 120, 1986.

    PubMed  CAS  Google Scholar 

  • Aplin, J.D.: Expression of integrin alpha 6 beta 4 in human trophoblast and its loss from extravillous cells. Placenta 14: 203–215, 1993.

    Article  PubMed  CAS  Google Scholar 

  • Aplin, J.D., and Campbell, S.: An immunofluorescence study of extracellular matrix associated with cytotrophoblast of the chorion laeve. Placenta 6: 469–479, 1985.

    Article  PubMed  CAS  Google Scholar 

  • Aplin, J.D., and Foden, L.J.: A cell spreading factor, abundant in human placenta, contains fibronectin and fibrinogen. J. Cell Sci. 58: 287–302, 1982.

    PubMed  CAS  Google Scholar 

  • Arias-Stella, J.: Gestational endometrium. In, The Uterus. H.J. Norris, A.T. Hertig, and M.R. Abel, eds., pp. 183–212. Williams and Wilkins, Baltimore, 1973.

    Google Scholar 

  • Arnholdt, H., and Löhrs, U.: Proliferation and differentiation of Langhans’ cells. Placenta 10: 458, 1989.

    Article  Google Scholar 

  • Arnholdt, H., Meisel, F., Fandrey, K., and Löhrs, U.: Proliferation of villous trophoblast of the human placenta in normal and abnormal pregnancies. Virchows Arch. B Cell Pathol. 60: 365–372, 1991.

    Article  CAS  Google Scholar 

  • Arnold, J.: Über den Schlussring reifer menschlicher Plazenten. Verh. Anat. Ges. 69: 303–306, 1975a.

    PubMed  CAS  Google Scholar 

  • Arnold, J.: Über die Randzone der reifen menschlichen Plazenta. Inaugural Dissertation, Würzburg, 1975b.

    Google Scholar 

  • Arts, N.F.T.: Investigations on the vascular system of the placenta. Am. J. Obstet. Gynecol. 82: 147–166, 1961.

    PubMed  CAS  Google Scholar 

  • Aufderheide E., and Ekblom, P.: Tenascin during gut development: appearance in the mesenchyme, shift in molecular forms, and dependence on epithelial-mesenchymal interactions. J. Cell Biol. 107: 2341–2349, 1988.

    Article  PubMed  CAS  Google Scholar 

  • Autio Harmainen, H., Hurskainen, T., Niskasaari, K., Hoyhtya, M., and Tryggvason, K.: Simultaneous expression of 70 kilodalton type IV collagenase and type IV collagen alpha 1 (IV) chain genes by cells of early human placenta and gestational endometrium. Lab. Invest. 67: 191–200, 1992.

    Google Scholar 

  • Avery, C.R., and Aterman, K.: Calcification of the basement-membrane of placental villi. J. Pathol. 103: 199–200, 1971.

    Article  PubMed  CAS  Google Scholar 

  • Azab, I., Okamura, H., and Beer, A.: Decidual cell production of human placental fibrinoid. Obstet. Gynecol. 40: 186–193, 1972.

    PubMed  CAS  Google Scholar 

  • Badarau, L., and Gavrilita, L.: Intervillous fibrin deposition, the Rohr, Nitabuch and Langhans striae. Am. J. Obstet. Gynecol. 98: 252–260, 1967.

    PubMed  CAS  Google Scholar 

  • Badarau, L., Gavrilita, L., Stratan, E., and Calinca, N.: Étude histologique de la caduque au cours de la grossesse normale: le mode de pénétration du trophoblaste dans la plaque basale; le processus de placentation. Gynecol. Obstet. (Paris) 70: 273–290, 1971.

    CAS  Google Scholar 

  • Bagshawe, K., and Lawler, S.: The immunogenicity of the placenta and trophoblast. In, Immunobiology of Trophoblast. R.G. Edwards, C.W.S. Howe, and M.H. Johnson, eds., pp. 171–182. Cambridge University Press, London, 1975.

    Google Scholar 

  • Baker, B.L., Hook, J., and Severinghaus, A.E.: The cytological structure of the human chorionic villus and decidua parietalis. Am. J. Anat. 74: 291–325, 1944.

    Article  Google Scholar 

  • Bardawil, W.A., and Toy, B.L.: The natural history of choriocarcinoma: problems of immunity and spontaneous regression. Ann. N.Y. Acad. Sci. 80: 197–261, 1959.

    Article  PubMed  CAS  Google Scholar 

  • Bargmann, W.: Über den Bildungsort der Choriongonadotropine und Plazentarsteroide. Geburtshilfe Frauenheilkd. 17: 865–875, 1957.

    PubMed  CAS  Google Scholar 

  • Bautzmann, H., and Schröder, R.: Vergleichende Studien über Bau und Funktion des Amnions: Neue Befunde am menschlichen Amnion mit Einschluss seiner freien Bindegewebs-oder sog. Hofbauerzellen. Z. Anat. 119: 722, 1955.

    Google Scholar 

  • Beck, A.J., and Beck, F.: The origin of intra-arterial cells in the pregnant uterus of the macaque (Macaca mulatta). Anat. Rec. 158: 111–113, 1967.

    Article  PubMed  CAS  Google Scholar 

  • Beck, J.S.: Time of appearance of human placental lactogen in the embryo. N. Engl. J. Med. 283: 189–190, 1970.

    Article  PubMed  CAS  Google Scholar 

  • Beck, T., Schweikhart, G., and Stolz, E.: Immunohistochemical location of HPL, SP1 and ß-HCG in normal placentas of varying gestational age. Arch. Gynecol. 239: 63–74, 1986.

    Article  PubMed  CAS  Google Scholar 

  • Becker, V.: Funktionelle Morphologie der Placenta. Arch. Gynecol. 198: 3–28, 1962.

    Google Scholar 

  • Becker, V.: Gefäße der Chorionplatte und Stammzotten. In, Die Plazenta des Menschen. V. Becker, T.H. Schiebler, and F. Kubli, eds., pp. 311–313. Thieme Verlag, Stuttgart, 1981.

    Google Scholar 

  • Becker, V., and Jipp, P.: Über die Trophoblastschale der menschlichen Plazenta. Geburtshilfe Frauenheilkd. 23: 466474, 1963.

    Google Scholar 

  • Bell, S.C.: Decidualization: regional differentiation and associated function. Oxford Rev. Reprod. Biol. 5: 220–271, 1983.

    Google Scholar 

  • Bell, S.C.: Decidualization and insulin-like growth factor (IGF) binding protein: implications for its role in stromal cell differentiation and the decidual cell in haemochorial placentation. Hum. Reprod. 4: 125–130, 1989.

    PubMed  CAS  Google Scholar 

  • Bell, S.C., Patel, S.R., Jackson, J.A., and Waites, G.T.: Major secretory protein of human decidualized endometrium in pregnancy is an insulin-like growth factor binding protein. J. Endocrinol. 118: 317–328, 1988.

    Article  PubMed  CAS  Google Scholar 

  • Bendon, R.W., and Ray, M.B.: The pathologic findings of the fetal membranes in very prolonged amniotic fluid leakage. Arch. Pathol. Lab. Med. 110: 47–50, 1986.

    PubMed  CAS  Google Scholar 

  • Benirschke, K.: Examination of the placenta. Obstet. Gynecol. 18: 309–333, 1961.

    Google Scholar 

  • Benirschke, K., and Driscoll, S.G.: The Pathology of the Human Placenta. Springer-Verlag, New York, 1967.

    Google Scholar 

  • Berger, G., Verbaere, J., and Feroldi, J.: Placental site trophoblastic tumor of the uterus: an ultrastructural and immunohistochemical study. Ultrastruct. Pathol. 6: 319329, 1984.

    Google Scholar 

  • Bertolini, R., and Klinger, M.: Über deziduaähnliche Zellnester in der Chorionplatte von geburtsreifen menschlichen Plazenten. Zentralbl. Gynäkol. 17: 521–524, 1966.

    Google Scholar 

  • Bertolini, R., Reissig, D., and Schippel, K.: Elektronenmikrokopische Befunde an den Zellen in der Chorionplatte der reifen menschlichen Plazenta. Z. Mikrosk. Anat. Forsch. 80: 358–368, 1969.

    PubMed  CAS  Google Scholar 

  • Bierings, M.B., Adriaansen, H.J., and Van Dijk, J.P.: The appearance of transferrin receptors on cultured human cytotrophoblast and in vitro-formed syncytiotrophoblast. Placenta 9: 387–396, 1988.

    Article  PubMed  CAS  Google Scholar 

  • Bigazzi, M., Bruni, P., Nardi, E., Petrucci, F., Pollicino, G., Franchini, M., Scarselli, G., and Farnararo, M.: Human decidual relaxin. Ann. N. Y. Acad. Sci. 380: 87–99, 1982.

    Article  PubMed  CAS  Google Scholar 

  • Billington, D.: Organization, ultrastructure and histochemistry of the placenta: immunological considerations. In, Immunobiology of Trophoblast. R.G. Edwards, C.W.S. Howe, and M.H. Johnson, eds. Cambridge University Press, Cambridge, 1975.

    Google Scholar 

  • Birkenfeld, A., Mordel, N., and Okon, E.: Direct demonstration of iron in a term placenta in a case of ß-thalassemia major. Am. J. Obstet. Gynecol. 160: 562–563, 1989.

    PubMed  CAS  Google Scholar 

  • Bischof, P., and Martelli, M.: Current topic: proteolysis in the penetration phase of the implantation process. Placenta 13: 17–24, 1992.

    Article  PubMed  CAS  Google Scholar 

  • Bischof, P., Friedli, E., Martelli, M., and Campana, A.: Expression of extracellular matrix-degrading metalloproteinases by cultured human cytotrophoblast cells: effects of cell adhesion and immunopurification. Am. J. Obstet. Gynecol. 165: 1791–1801, 1991.

    PubMed  CAS  Google Scholar 

  • Bittencourt, A.L., and Sadigursky, M.: Decidual angiomatosis with abortion. Patologia (Mexico) 15: 45–47, 1977.

    Google Scholar 

  • Björkman, N.: On the fine structure of the porcine placental barrier. Acta Anat. (Basel) 62: 334–342, 1965a.

    Google Scholar 

  • Björkman, N.: The fine morphology of the area of foetal-maternal apposition in the equine placenta. Z. Zellforsch. 65: 285–289, 1965b.

    Google Scholar 

  • Björkman, N.: An Atlas of Placental Fine Structure. Baillière, London; Williams and Wilkins, Baltimore, 1970.

    Google Scholar 

  • Björkman, N., and Bloom, G.: On the fine structure of the foetal-maternal junction on the bovine placentome. Z. Zellforsch. 45: 649–659, 1957.

    PubMed  Google Scholar 

  • Blankenship, T.N., Enders, A.C., and King, B.F.: Trophoblastic invasion and the development of uteroplacental arteries in the macaque: immunohistochemical localization of cytokeratins, desmin, type IV collagen, laminin, and fibronectin. Cell Tissue Res. 272: 227–236, 1993a.

    Article  PubMed  CAS  Google Scholar 

  • Blankenship, T.N., Enders, A.C., and King, B.F.: Trophoblastic invasion and modification of uterine veins during placental development in macaques. Cell Tiss. Res. 274: 135–144, 1993b.

    CAS  Google Scholar 

  • Blithe, D.L., Richards, R.G., and Skarulis, M.C.: Free alpha molecules from pregnancy stimulate secretion of prolactin from human decidual cells: a novel function for free alpha in pregnancy. Endocrinology 129: 2257–2259, 1991.

    Article  PubMed  CAS  Google Scholar 

  • Boe, F.: Studies on the human placenta. I. The cell islands in the young placenta. Acta Obstet. Gynecol. Scand. 46: 59 1603, 1967.

    Google Scholar 

  • Boeving, B.G.: Das Eindringen des Trophoblasten in das Uterusepithel. Klin. Wochenschr. 42: 467–475, 1964.

    Article  PubMed  CAS  Google Scholar 

  • Bogaert, L.J.: Endometrial granulocytes in proliferative endometrium. Br. J. Obstet. Gynaecol. 82: 995–998, 1975.

    Article  PubMed  Google Scholar 

  • Bohn, H.: The human fibrin-stabilizing factors. Mol. Cell. Biochem. 20: 67–75, 1978.

    Article  PubMed  CAS  Google Scholar 

  • Bonashevskaia, T.I., Lamentova, T.G., Shmakov, G.S., Nikolaeva, E.G., and Suslova, V.M.: Structuro-functional changes in the placenta as a result of exposure to atmospheric pollutants. Arkh. Anat. Gistol. Embriol. 88: 72–76, 1985.

    PubMed  CAS  Google Scholar 

  • Bonnar, J., and Sheppard, B.L.: Treatment of poor intrauterine fetal growth with heparin and dipyridamole. Minerva Med. 465–468, 1977.

    Google Scholar 

  • Bore11, U., Fernstroem, I., Ohlson, L., and Wiqvist, N.: Effect of uterine contractions on the uteroplacental blood flow at term. Am. J. Obstet. Gynecol. 93: 44–57, 1965.

    Google Scholar 

  • Borsi, L., Carnemolla, B., Castellani, P., Rossellini, C., Vecchio, D., Allemanni, G., Change, S.E., TaylorPapadimitriou, J., Pande H., and Zardi, L.: Monoclonal antibodies in the analysis of fibronectin isoforms generated by alternative splicing of mRNA precursors in normal and transformed human cells. J. Cell Biol. 104: 595–600, 1987.

    Article  PubMed  CAS  Google Scholar 

  • Boume, G.L.: The Human Amnion and Chorion. Lloyd-Luke, London, 1962.

    Google Scholar 

  • Boyd, J.D.: Morphology and physiology of the utero-placental circulation. In, Gestation. C.A. Villee, ed., pp. 132–194, Macy. New York, 1956.

    Google Scholar 

  • Boyd, J.D., and Hamilton, W.J.: The giant cells of the pregnant human uterus. J. Obstet. Gynaecol. Br. Emp. 67: 208–218, 1960.

    Article  PubMed  CAS  Google Scholar 

  • Boyd, J.D., and Hamilton, W.J.: Placental septa. Z. Zellforsch. 69: 613–634, 1966.

    Article  PubMed  CAS  Google Scholar 

  • Boyd, J.D., and Hamilton, W.J.: The Human Placenta. Heifer and Sons, Cambridge, 1970.

    Google Scholar 

  • Bradbury, S., Billington, W.D., and Kirby, D.R.S.: A histochemical and electron microscopical study of the mouse placenta. J.R. Microsc. Soc. 84: 199–211, 1965.

    Article  CAS  Google Scholar 

  • Bray, B.A.: Presence of fibronectin in basement membranes and acidic structural glycoproteins from human placenta and lung. Ann. N.Y. Acad. Sci. 312: 142–150, 1978.

    Article  PubMed  CAS  Google Scholar 

  • Bret, A.-J., Legros, R., and Toyoda, S.: Les kystes placentaires. Press Md. 68: 1552–1555, 1960.

    Google Scholar 

  • Brettner, A.: Zum Verhalten der sekundären Wand der Utero-Plazentargefässe bei der decidualen Reaktion. Acta Anat. (Basel) 57: 367–376, 1964.

    Google Scholar 

  • Breus, C.: Das Tuberöse Subchoriale Hämatom der Decidua. Eine typische Form der Molenschwangerschaft. F. Deuticke, Leipzig, 1892.

    Google Scholar 

  • Briese, V., and Müller, H.: Fetomaternal signal transduction by growth factors. Zentralbi. Gynakol. 114: 219–223, 1992.

    CAS  Google Scholar 

  • Brosens, I.: A study of the spiral arteries of the decidua basalis in normotensive and hypertensive pregnancies. J. Obstet. Gynaecol. Br. Commonw. 71: 222–230, 1964.

    Article  PubMed  CAS  Google Scholar 

  • Brosens, I.: The utero-placental vessels at term—the distribution and extent of physiological changes. Trophoblast Res. 3: 61–68, 1988.

    Google Scholar 

  • Brosens, I., Robertson, W.B., and Dixon, H.G.: The physiological response of the vessels of the placental bed to normal pregnancy. J. Pathol. Bacteriol. 93: 569–579, 1967.

    Article  PubMed  CAS  Google Scholar 

  • Brosens, I., Robertson, W.B., and Dixon, H.G.: The role of the spiral arteries in the pathogenesis of preeclampsia. Obstet. Gynecol. Ann. 1: 177–191, 1972.

    CAS  Google Scholar 

  • Brosens, I., Dixon, H.G., and Robertson, W.B.: Fetal growth retardation and the arteries of the placental bed. Br. J. Obstet. Gynaecol. 84: 656–663, 1977.

    PubMed  CAS  Google Scholar 

  • Brown, H.L., Miller, J.M., Khawli, O., and Gabert, H.A.: Premature placental calcification in maternal cigarette smokers. Obstet. Gynecol. 71: 914–917, 1988.

    PubMed  CAS  Google Scholar 

  • Bryant-Greenwood, G.D., Rees, M.C.P., and Turnbull, A.C.: Immunohistochemical localization of relaxin, prolactin and prostaglandin synthase in human amnion, chorion and decidua. J. Endocrinol. 114: 491–496, 1987.

    Article  PubMed  CAS  Google Scholar 

  • Brzosko, W., Nowoslawski, A., and Pisarki, T.: Analiza immunohistochemiczna mas wloknikowatych w lozysku ludzkim. Ginekol. Polska 36: 121–130, 1965a.

    CAS  Google Scholar 

  • Brzosko, W., Nowoslawski, A., and Pisarski, I.: Immunohistochemical analysis of the fibrinoid masses in human placenta. Pol. Med. 5: 114–123, 1965b.

    Google Scholar 

  • Bühler, F.R.: Randbildungen der menschlichen Placenta. Acta Anat. (Basel) 59: 47–76, 1964.

    Google Scholar 

  • Bullen, B., and Bloxam, D.: Human placental trophoblast cultured on amnion basement membrane: a model for transport studies. In, Abstracts of the 11th Rochester Trophoblast Conference, p. 131, 1988.

    Google Scholar 

  • Bulmer, D.: The metrial gland and endometrial granulocytes. J. Anat. 137: 787–826, 1983.

    Google Scholar 

  • Bulmer, D., and Dickson, A.D.: The fibrinoid capsule of the rat placenta and the disappearance of the decidua. J. Anat. 95: 300–310, 1961.

    PubMed  CAS  Google Scholar 

  • Bulmer, D., and Peel, S.: The demonstration of immunoglobulin in the metrial gland cells of the rat placenta. J. Reprod. Fertil. 49: 143–145, 1977.

    Article  PubMed  CAS  Google Scholar 

  • Bulmer, D., Stewart, I., and Peel, S.: Endometrial granulocytes of the pregnant hamster. J. Anat. 136: 329–337, 1983.

    PubMed  CAS  Google Scholar 

  • Bulmer, J.N., and Johnson, P.M.: Macrophage populations in the human placenta and amniochorion. Clin. Exp. Immunol. 57: 393–403, 1984.

    PubMed  CAS  Google Scholar 

  • Bulmer, J.N., and Sunderland, C.A.: Bone-marrow origin of endometrial granulocytes in the early human placental bed. J. Reprod. Immunol. 5: 383–387, 1983.

    Article  PubMed  CAS  Google Scholar 

  • Bulmer, J.N., and Sunderland, C.A.: Immunohistological characterization of lymphoid cell populations in the early human placental bed. Immunology 52: 349–357, 1984.

    PubMed  CAS  Google Scholar 

  • Bulmer, J.N., Wells, M., Bhabra, K., and Johnson, P.M.: Immunohistological characterization of endometrial gland epithelium and extravillous fetal trophoblast in third trimester human placental bed tissues. Br. J. Obstet. Gynaecol. 93: 823–832, 1986.

    Article  PubMed  CAS  Google Scholar 

  • Bulmer, J.N., Johnson, P.M., Sasagawa, M., and Takeuchi, S.: Immunohistochemical studies of fetal trophoblast and maternal decidua in hydatidiform mole and choriocarcinoma. Placenta 9: 183–200, 1988a.

    Article  PubMed  CAS  Google Scholar 

  • Bulmer, J.N., Morrison, L., and Smith, J.C.: Expression of class II MHC gene products by macrophages in human uteroplacental tissue. Immunology 63: 707–714, 1988b.

    PubMed  CAS  Google Scholar 

  • Bulmer, J.N., Smith, J., Morrison, L., and Wells, M.: Maternal and fetal cellular relationships in the human placental basal plate. Placenta 9: 237–246, 1988c.

    Article  PubMed  CAS  Google Scholar 

  • Bulmer, J.N., Thrower, S., and Wells, M.: Expression of epidermal growth factor receptor and transferrin receptor by human trophoblast populations. Am. J. Reprod. Immunol. 21: 87–93, 1989.

    PubMed  CAS  Google Scholar 

  • Bumm, E.: Zur Kenntnis der Uteroplacentargefässe. Arch. Gynäkol. 37: 1–15, 1890.

    Article  Google Scholar 

  • Bunton, T.E.: Incidental lesions in nonhuman primate placentae. Vet. Pathol. 23: 431–438, 1986.

    Article  PubMed  CAS  Google Scholar 

  • Burrows, T.D., King, A., and Loke, Y.W.: Expression of integrins by human trophoblast and differential adhesion to laminin or fibronectin. Hum. Reprod. 8: 475–484, 1993.

    PubMed  CAS  Google Scholar 

  • Burstein, R., Frankel, S., Soule, S.D., and Blumenthal, H.T.: Ageing in the placenta: autoimmune theory of senescence. Am. J. Obstet. Gynecol. 116: 271–274, 1973.

    PubMed  CAS  Google Scholar 

  • Busanny-Caspari, W.: Zur Morphogenese des Fibrinoids in Placenta und Decidua. Virchows Arch. 322: 452–460, 1952.

    Article  PubMed  CAS  Google Scholar 

  • Busanny-Caspari, E.: Zur Morphologie des Fibrinoids in Placenta und Dezidua. Virchows Arch. [Pathol. Anat.] 322: 452–460, 1956.

    Google Scholar 

  • Busanny-Caspari, W.: Fibrin und Fibrinoid. Acta Histochem. 4: 304–313, 1957.

    PubMed  CAS  Google Scholar 

  • Butterworth, B.H., Khong, T.Y., Loke, Y.W., and Robertson, W.B.: Human cytotrophoblast populations studied by monoclonal antibodies using single and double biotinavidin-peroxidase immunocytochemistry. J. Histochem. Cytochem. 33: 977–983, 1985.

    Article  PubMed  CAS  Google Scholar 

  • Carnemolla, B., Borsi, L., Zardi, L., Owens, R.J., and Baralle, F.E.: Localization of the cellular-fibronectinspecific epitope recognized by the monoclonal antibody IST-9 using fusion proteins expressed in E. coli. FEBS Lett. 215: 269–273, 1987.

    Article  CAS  Google Scholar 

  • Carnemolla, B., Balza, E., Siri, A., Zardi, L., Nicotra, M.R., Bigotti, A., and Natali, P.G.: A tumor associated fibronectin isoform generated by alternative splicing of messenger RNA precursors. J. Cell Biol. 108: 1139–1148, 1989.

    Article  PubMed  CAS  Google Scholar 

  • Carter, J.E., Vellios, F., and Huber, C.P.: Histologic classification and incidence of circulatory lesions of the human placenta, with a review of the literature. Am. J. Clin. Pathol. 40: 374–378, 1963.

    Google Scholar 

  • Casey, M.L., Delgadillo, M., Cox, K.A., Nisert, S., and MacDonald, P.C.: Inactivation of prostaglandins in human decidua vera (parietalis) tissue: substrate specificity of prostaglandin dehydrogenase. Am. J. Obstet. Gynecol. 160: 3–7, 1989.

    PubMed  CAS  Google Scholar 

  • Castellucci, M., Kaufmann, P., and Bischof, P.: Extracellular matrix influences hormone and placental protein production by human chorionic villi. In, Abstracts of the 11th Rochester Trophoblast Conference, p. 49, 1988.

    Google Scholar 

  • Castellucci, M., Kaufmann, P., and Bischof, P.: Extracellular matrix influences hormone and protein production by human chorionic villi. Cell Tissue Res. 262: 135–142, 1990.

    Article  PubMed  CAS  Google Scholar 

  • Castellucci, M., Classen Linke, I., Mühlhauser, J., Kaufmann, P., and Zardi, L.: The human placenta: a model for tenascin expression. Histochemistry 95: 449–458, 1991.

    Article  PubMed  CAS  Google Scholar 

  • Castellucci, M., Crescimanno, C., Schröter, C.A., Kaufmann, P., and Mühlhauser, J.: Extravillous trophoblast: immunohistochemical localization of extracellular matrix molecules. In, Frontiers in Gynecologic and Obstetric Investigation. A.R. Genazzani, F. Petraglia, and A.D. Genazzani, eds., pp. 19–25. Parthenon, New York, 1993a. (p. 297 ).

    Google Scholar 

  • Castellucci, M., Crescimano, C., Mühlhauser, J., Frank, H.G., Kaufmann, P., and Zardi, L.: Expression of extracellular matrix molecules related to placental development. Placenta 14: A9, 1993b.

    Article  Google Scholar 

  • Chaouat, G., Kolb, J.P., and Wegmann, T.G.: The murine placenta as an immunological barrier between the mother and the fetus. Immunol. Rev. 75: 31–60, 1983.

    Article  PubMed  CAS  Google Scholar 

  • Cheung, P.Y., Walton, J.C., Tai, H.H., Riley, S.C., and Challis, J.R.: Immunocytochemical distribution and localization of 15-hydroxyprostaglandin dehydrogenase in human fetal membranes, decidua, and placenta. Am. J. Obstet. Gynecol. 163: 1445–1449, 1990.

    PubMed  CAS  Google Scholar 

  • Cheung, P.Y., Walton, J.C., Tai, H.H., Riley, S.C., and Challis, J.R.: Localization of 15-hydroxy prostaglandin dehydrogenase in human fetal membranes, decidua, and placenta during pregnancy. Gynecol. Obstet. Invest. 33: 142–146, 1992.

    Article  PubMed  CAS  Google Scholar 

  • Chiquet-Ehrismann, R., Mackie, E.J., Pearson, C.A., and Sakakura, T.: Tenascin: an extracellular matrix protein involved in tissue interactions during fetal development and oncogenesis. Cell 47: 131–139, 1986.

    Article  PubMed  CAS  Google Scholar 

  • Chung, Si: Comparative studies on tissue transglutaminase and factor XIII. Ann. N.Y. Acad. Sci. 202: 240–255, 1972.

    Article  PubMed  CAS  Google Scholar 

  • Clewell, W.H., and Manchester, D.K.: Recurrent maternal floor infarction: a preventable cause of fetal death. Am. J. Obstet. Gynecol. 147: 346–347, 1983.

    PubMed  CAS  Google Scholar 

  • Coleman, R.W., Marder, V.J., Salzman, E.W., and Hirsh, J.: Overview of hemostasis. In, Hemostasis and Thrombosis, 2nd ed. R.W. Coleman, J. Hirsh, V.J. Marder, and E.W. Salzman, eds., pp. 3–17. Lipincott, Philadelphia 1987.

    Google Scholar 

  • Coukos, G., Gafvels, M.E., Wisel, S., Ruelaz, E.A., Strickland, D.K., Strauss, J.F., and Coutifaris, C.: Expression of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein and the 39-kd receptor-associated protein in human trophoblasts. Am. J. Pathol. 144: 383–392, 1994.

    PubMed  CAS  Google Scholar 

  • Currie, C.A., and Bagshawe, K.D.: The masking of antigens on trophoblast and cancer cells. Lancet 1: 708–710, 1967.

    Article  PubMed  CAS  Google Scholar 

  • Dallenbach, F.D., and Dallenbach-Hellweg, G.: Immunohistologische Untersuchungen zur Lokalisation des Relaxins in menschlicher Placenta und Decidua. Virchows Arch. [Pathol. Anat.] 337: 301–316, 1964.

    CAS  Google Scholar 

  • Dallenbach-Hellweg, G.: Histopathology of the Endometrium. pp. 24–27. Springer-Verlag, Berlin, 1971.

    Google Scholar 

  • Dallenbach-Hellweg, G., and Nette, G.: Über Glykoproteideinschlüsse in den Trophoblastzellen der menschlichen Plazenta und die Frage ihres Zusammenhangs mit der Bildung von Gonadotropin. Z. Zellforsch. 61: 145–158, 1963a.

    Article  PubMed  CAS  Google Scholar 

  • Dallenbach-Hellweg, G., and Nette, G.: Über Proteineinschlüsse in basalen Trophoblastzellen der reifen menschlichen Plazenta. Virchows Arch. [Pathol. Anat.] 336: 528–543, 1963b.

    CAS  Google Scholar 

  • Dallenbach-Hellweg, G., and Nette, G.: Morphological and histochemical observations on trophoblast and decidua of the basal plate of the human placenta at term. Am. J. Anat. 115: 309–326, 1964.

    Article  PubMed  CAS  Google Scholar 

  • Dallenbach-Hellweg, G., and Sievers, S.: Die histologische Reaktion des Endometrium auf lokal applizierte Gestagene. Virchows Arch. [Pathol. Anat.] 368: 289–298, 1975.

    CAS  Google Scholar 

  • Daly, D.C., Maslar, I.A., and Riddick, D.H.: Prolactin production during in vitro decidualization of proliferative endometrium. Am. J. Obstet. Gynecol. 145: 672–678, 1983.

    PubMed  CAS  Google Scholar 

  • Damjanov, I.: Editorial: Vesalius and Hunter were right: decidua is a membrane. Lab. Invest. 53: 597–598, 1985.

    PubMed  CAS  Google Scholar 

  • Damsky, C.H., Fitzgerald, M.L., and Fisher, S.J.: Distribution patterns of extracellular matrix components and adhesion receptors are intricately modulated during first trimester cytotrophoblast differentiation along the invasive pathway, in vivo. J. Clin. Invest. 89: 210–222, 1992.

    Article  PubMed  CAS  Google Scholar 

  • Davies, B.R., Casanueva, E., and Arroyo, P.: Placentas of small-for-dates infants: a small controlled series from Mexico City, Mexico. Am. J. Obstet. Gynecol. 149: 73 1736, 1984.

    Google Scholar 

  • Daya, D., and Sabet, L.: The use of cytokeratin as a sensitive and reliable marker for trophoblastic tissue. Am. J. Clin. Pathol. 95: 137–141, 1991.

    PubMed  CAS  Google Scholar 

  • De Bakker-Theunissen, O.J.G.B., Arts, N.F.T., and Mulder, G.H.: Fluid transport across human fetal membranes affected by human amniotic fluid prolactin: an in vitro study. Placenta 9: 533–545, 1988.

    Article  Google Scholar 

  • Debiasi, E., Damiani, N., and Capodacqua, R.: Contributo allo studio della circolazione utero-placentare nelle donna. Minerva Ginecol. 15: 539–545, 1963.

    PubMed  CAS  Google Scholar 

  • Demir, R., and Erbengi, T.: The cells of the intercotyledonary septae in full-term placenta. In, Proceedings of the 8th European Congress of Electron Microscopy. Vol. 3. pp. 2017–2018, 1984.

    Google Scholar 

  • Dempsey, E.W., Wislocki, G.B., and Amoroso, E.C.: Electron microscopy of the pig’s placenta, with especial reference to the cell membranes of the endometrium and chorion. Am. J. Anat. 96: 65–102, 1955.

    Article  PubMed  CAS  Google Scholar 

  • Dempsey, E.W., Lessey, R.A., and Luse, S.A.: Electron microscopic observations on fibrinoid and histiotroph in the junctional zone and villi of the human placenta. Am. J. Anat. 108: 463–484, 1970.

    Article  Google Scholar 

  • Denker, H.W.: The role of trophoblastic factors in implantation. In, Novel Aspects of Reproductive Physiology. C.H. Spilman and J.W. Wilks, eds., pp. 181–212. Spectrum, New York, 1978.

    Google Scholar 

  • Denker, H.-W.: Trophoblast-endometrial interactions at embryo implantation: a cell biological paradox. Trophoblast Res. 4: 1–27, 1990.

    Google Scholar 

  • Denker, H.-W., and Aplin, J.D. eds.: Trophoblast invasion and endometrial receptivity: novel aspects of the cell biology of embryo implantation. Trophoblast Res. 4:1–462, 1990.

    Google Scholar 

  • DeWolf, F., DeWolf-Peeters, C., and Brosens, I.: Ultrastructure of the spiral arteries in the human placental bed at the end of normal pregnancy. Am. J. Obstet. Gynecol. 117: 833–848, 1973.

    CAS  Google Scholar 

  • DeWolf, F., Brosens, I., and Renaer, M.: Fetal growth retardation and the maternal arterial supply of the human placenta in the absence of sustained hypertension. Br. J. Obstet. Gynaecol. 87: 678–685, 1980.

    Article  CAS  Google Scholar 

  • Dietl, J., Ruck, P., Horny, H.P., Handgretinger, R., Marzusch, K., Ruck, M., Kaiserling, E., Griesser, H., and Kabelitz, D.: The decidua of early human pregnancyimmunohistochemistry and function of immunocompetent cells. Gynecol. Obstet. Invest. 33: 197–204, 1992.

    Article  PubMed  CAS  Google Scholar 

  • Dohrn, M.: Ein Beitrag zur mikroskopischen Anatomie der reifen menschlichen Eihüllen. Monatsschr. Geburtshilfe Frauenkr. 26: 114–127, 1865.

    Google Scholar 

  • Doolittle, R.F.: Fibrinogen and fibrin. In, The Plasma Proteins. 2nd Ed., Vol. 2. F.W. Putnam, ed., pp. 109–161. Academic Press, Orlando, FL, 1975.

    Google Scholar 

  • Douglas, G.C., and King, B.F.: Isolation of pure villous cytotrophoblast from term human placenta using immunomagnetic microspheres. J. Immunol. Methods 119: 259–268, 1989.

    Article  PubMed  CAS  Google Scholar 

  • Douglas, G.C., and King, B.F.: Differentiation of human trophoblast cells in vitro as revealed by immunocytochemical staining of desmoplakin and nuclei. J. Cell Sci. 96: 131–141, 1990a.

    PubMed  Google Scholar 

  • Douglas, G.C., and King, B.F.: Isolation and morphologic differentiation in vitro of villous cytotrophoblast cells from rhesus monkey placenta. In Vitro Cell Dev. Biol. 26:754758, 1990b.

    Google Scholar 

  • Douglas, G.C., and King, B.F.: Colchicine inhibits human trophoblast differentiation in vitro. Placenta 14: 187–201, 1993.

    Article  PubMed  CAS  Google Scholar 

  • Duan, J.S.: Production of granulocyte colony stimulating factor in decidual tissue and its significance in pregnancy. Osaka City Med. J. 36: 81–97, 1990.

    PubMed  CAS  Google Scholar 

  • Duncan, D.A., and Mazur, M.T.: Trophoblastic tumors: ultrastructural comparison of choriocarcinoma and placental-site trophoblastic tumor. Hum. Pathol. 20: 370–381, 1989.

    Article  PubMed  CAS  Google Scholar 

  • Durst-Zivkovic, B.: Endometrial granular cells in fetal membranes. Anat. Anz. 143: 258–261, 1978.

    PubMed  CAS  Google Scholar 

  • Dvorak, H.F., Senger, D.R., and Dvorak, A.M.: Fibrin as a component of the tumor stroma: origins and biological significance. Cancer Metastasis Rev. 2: 41–73, 1983.

    Article  PubMed  CAS  Google Scholar 

  • Earl, U., Wells, M., and Bulmer, J.N.: The expression of major histocompatibility complex antigens by trophoblast in ectopic tubal pregnancy. J. Reprod. Immunol. 8: 13–24, 1985.

    Article  PubMed  CAS  Google Scholar 

  • Earl, U., Morrison, L., Gray, C., and Bulmer, J.N.: Proteinase and proteinase inhibitor localization in the human placenta. Int. J. Gynecol. Pathol. 8: 114–124, 1989.

    Article  PubMed  CAS  Google Scholar 

  • Earl, U., Estlin, C., and Bulmer, J.N.: Fibronectin and laminin in the early human placenta. Placenta 11: 223–231, 1990.

    Article  PubMed  CAS  Google Scholar 

  • Edwards, D., Jones, C.J.P., Sibley, C.P., Farmer, D.R., and Nelson, D.M.: Areas of syncytial denudation may provide routes for paracellular diffusion across the human placenta [abstract]. Placenta 12: 383, 1991.

    Google Scholar 

  • Ehrig, K., Leivo, I., Argraves, W.S., Ruoslahti, E., and Engvall, E.: Merosin, a tissue-specific basement membrane protein, is a laminin-like protein. Proc. Natl. Acad. Sci. U.S.A. 87: 3264–3268, 1990.

    Article  PubMed  CAS  Google Scholar 

  • Eidelman, S., Damsky, C.H., Wheelock, M.J., and Damjanov, I.: Expression of the cell-cell adhesion glycoprotein cell-CAM 120/80 in normal human tissues and tumors. Am. J. Pathol. 135: 101–110, 1989.

    PubMed  CAS  Google Scholar 

  • Einbrodt, H.J., and Schmid, K.O.: Über abnorme Verkalkungen der menschlichen Placenta bei Maternitätstetanie. Arch. Gynecol. 200: 327–339, 1965.

    CAS  Google Scholar 

  • Einbrodt, H.J., Schiereck, F.W., and Kinny, H.: Über die Ablagerung von Blei in den Verkalkungen der menschlichen Placenta. Arch. Gynecol. 213: 303–306, 1973.

    CAS  Google Scholar 

  • Ellis, S.A., Sargent, I.L., Redman, C.W., and McMichael, A.J.: Evidence for a novel HLA antigen found on human extravillous trophoblast and a choriocarcinoma cell line. Immunology 59: 595–601, 1986.

    PubMed  CAS  Google Scholar 

  • Ellis, S.A., Palmer, M.S., and McMichael, A.J.: Human trophoblast and the choriocarcinoma cell line BeWo express a truncated HLA Class I molecule. J. Immunol. 144: 73 1735, 1990.

    Google Scholar 

  • Emonard, H., Christiane, Y., Smet, M., Grimaud, J.A., and Foidart, J.M.: Type IV and interstitial collagenolytic activities in normal and malignant trophoblast cells are specifically regulated by the extracellular matrix. Invasion Metastasis 10: 170–177, 1990.

    PubMed  CAS  Google Scholar 

  • Enders, A.C.: Fine structure of anchoring villi of the human placenta. Am. J. Anat. 122: 419–452, 1968.

    Article  PubMed  CAS  Google Scholar 

  • Enders, A.C.: Current topic: structural responses of the primate endometrium to implantation. Placenta 12: 309325, 1991.

    Google Scholar 

  • Enders, A.C., and Schlafke, S.: Cytological aspects of trophoblast-uterine interaction in early implantation. Am. J. Anat. 125: 1–30, 1969.

    Article  PubMed  CAS  Google Scholar 

  • Ermocilla, R., and Altshuler, G.: The origin of “X cells” of the human placenta and their possible relationship to intrauterine growth retardation: an enigma. Am. J. Obstet. Gynecol. 117: 1137–1140, 1973.

    PubMed  CAS  Google Scholar 

  • Faller, T., and Ferenci, P.: Der Aubau der Placenta-Septen: Untersuchungen mit Hilfe der Quinacrinfluorescenzfärbung des Y-Chromatins. Z. Anat. Entwicklungsgesch. 142: 207217, 1973.

    Google Scholar 

  • Farmer, D.R., and Nelson, D.M.: A fibrin matrix modulates the proliferation, hormone secretion and morphologic differentiation of cultured human placental trophoblast. Placenta 13: 163–177, 1992.

    Article  PubMed  CAS  Google Scholar 

  • Faulk, W.P.: Placental fibrin. Am. J. Reprod. Immunol. 19: 132–135, 1989.

    PubMed  CAS  Google Scholar 

  • Faulk, P., Trenchev, P., Dorling, J., and Holborow, J.: Antigens on post-implantation placentae. In, Immunobiology of Trophoblast. R.G. Edwards, C.W.S. Howe, and M.H. Johnson, eds., pp. 113–130. Cambridge University Press, Cambridge, 1975.

    Google Scholar 

  • Fazleabas, A.T., Verhage, H.G., Waites, G., and Bell, S.C.: Characterization of an insulin-like growth factor binding protein, analogous to human pregnancy-associated secreted endometrial alpha 1-globulin, in decidua of the baboon (Papio anubis) placenta. Biol. Reprod. 40: 873–885, 1989.

    Article  PubMed  CAS  Google Scholar 

  • Feinberg, R.F., and Kliman, H.J.: Tropho-uteronectin (TUN): a unique oncofetal fibronectin deposited in the extracellular matrix of the tropho-uterine junction and regulated in vitro by cultured human trophoblast cells. Trophoblast Res. 7: 167–181, 1993.

    CAS  Google Scholar 

  • Feinberg, R.F., Kao, L.C., Haimowitz, J.E., Queenan, J.T., Jr., Wun, T.C., Strauss, J.F., and Kliman, H.J.: Plasminogen activator inhibitor types 1 and 2 in human trophoblasts: PAI-1 is an immunocytochemical marker of invading trophoblasts. Lab. Invest. 61: 20–26, 1989.

    PubMed  CAS  Google Scholar 

  • Feinberg, R.F., Kliman, H.J., and Cohen, A.W.: Pre-eclampsia, trisomy 13, and the placental bed. Obstet. Gynecol. 78: 505–508, 1991a.

    PubMed  CAS  Google Scholar 

  • Feinberg, R.F., Kliman, H.J., and Lockwood, C.J.: Is oncofetal fibronectin a trophoblast glue for human implantation ? Am. J. Pathol. 138: 537–543, 1991b.

    PubMed  CAS  Google Scholar 

  • Fisher, S., Rikover, M., and Naor, S.: Factor XIII deficiency

    Google Scholar 

  • with severe haemorrhagic diathesis. Blood 28:34–39, 1966. Fisher, S.J., and Damsky, C.H.: Human cytotrophoblast

    Google Scholar 

  • invasion. Semin. Cell Biol. 4: 183–188, 1993.

    Google Scholar 

  • Fisher, S.J., Leitch, M.S., Kantor, M.S., Basbaum, C.B., and Kramer, R.H.: Degradation of extracellular matrix by the trophoblastic cells of first-trimester human placentas. J. Cell Biochem. 27: 31–41, 1985.

    Article  PubMed  CAS  Google Scholar 

  • Fisher, S.J., Cui, T.Y., Zhang, L., Hartman, L., Grahl, K., Guo-Yang, Z., Tarpey, J., and Damsky, C.H.: Adhesive and degradative properties of human placental cytotrophoblast cells in vitro. J. Cell Biol. 109: 891–902, 1989.

    Article  PubMed  CAS  Google Scholar 

  • Fisher, S.J., Librach, C., Zhou, Y., Dao, D., Kosten, K., Roth, I., Bass, K., and Damsky, C.H.: Regulation of human cytotrophoblast invasion. Placenta 13:A. 17, 1992.

    Google Scholar 

  • Fox, H.: White infarcts of the placenta. J. Obstet. Gynaecol. Br. Commonw. 70: 980–991, 1963.

    Article  PubMed  CAS  Google Scholar 

  • Fox, H.: Calcification of the placenta. J. Obstet. Gynaecol. Br. Commonw. 71: 759–765, 1964.

    Article  PubMed  CAS  Google Scholar 

  • Fox, H.: Perivillous fibrin deposition in the human placenta. Am. J. Obstet. Gynecol. 98: 245–251, 1967a.

    PubMed  CAS  Google Scholar 

  • Fox, H.: The significance of placental infarction in perinatal morbidity and mortality. Biol. Neonate 11: 87–105, 1967b.

    Article  CAS  Google Scholar 

  • Fox, H.: Fibrinoid necrosis of placental villi. J. Obstet. Gynaecol. Br. Commonw. 75: 448–452, 1968.

    Article  PubMed  CAS  Google Scholar 

  • Fox, H.: Effect of hypoxia on trophoblast in organ culture. Am. J. Obstet. Gynecol. 107: 1058–1064, 1970.

    PubMed  CAS  Google Scholar 

  • Fox, H.: Pathology of the Placenta. Saunders, London, 1978.

    Google Scholar 

  • Frame, L.T., Wiley, L., and Rogol, A.D.: Indirect immunofluorescent localization of prolactin to the cytoplasm of decidua and trophoblast cells in human placental membranes at term. J. Clin. Endocrinol. Metab. 49: 435–437, 1979.

    Article  PubMed  CAS  Google Scholar 

  • Frank, H.G., Malekzadeh, F., Kertschanska, S., Crescimanno, C., Castellucci, M., Lang, I., Desoye, G., and Kaufmann, P.: Immunohistochemistry of two different types of placental fibrinoid. Acta Anat. (Basel) 150: 55–68, 1994.

    CAS  Google Scholar 

  • Franken, H.: Beitrag zur Veranschaulichung von Struktur und Funktion der Plazenta. Zentralbl. Gynäkol. 76: 729–745, 1954.

    PubMed  CAS  Google Scholar 

  • Freese, U.E.: The uteroplacental vascular relationship in the human. Am. J. Obstet. Gynecol. 101: 8–16, 1968.

    PubMed  CAS  Google Scholar 

  • Freese, U.E., and Maciolek, B.J.: Plastoid injection studies of the uteroplacental vascular relationship in the human. Obstet. Gynecol. 33: 160–169, 1969.

    PubMed  CAS  Google Scholar 

  • Fuchs, A.R., and Fuchs, F.: Endocrinology of human parturition: a review. Br. J. Obstet. Gynaecol. 91: 948–967, 1984.

    Article  PubMed  CAS  Google Scholar 

  • Fujikura, T.: Placental calcification and maternal age. Am. J. Obstet. Gynecol. 87: 41–45, 1963a.

    PubMed  CAS  Google Scholar 

  • Fujikura, T.: Placental calcification and seasonal difference. Am. J. Obstet. Gynecol. 87: 46–47, 1963b.

    PubMed  CAS  Google Scholar 

  • Fukamatsu, Y., Tornita, K., and Fukuta, T.: Further evidence of prolactin production from human decidua and its transport across fetal membrane. Gynecol. Obstet. Invest. 17: 309–316, 1984.

    Article  PubMed  CAS  Google Scholar 

  • Garel, J.-M., and Barlet, J.-P.: Calcitonin in the mother, fetus and newborn. Ann. Biol. Anim. Biochem. Biophys. 18: 53–68, 1978.

    Article  CAS  Google Scholar 

  • Geller, H.F.: Über die Bedeutung des subchorialen Fibrinstreifens in der menschlichen Plazenta. Arch. Gynecol. 192: 1–6, 1959.

    CAS  Google Scholar 

  • Genbacev, O., Papic, N., Cuperlovic, M., Vicovac, L., Vuckovic, M., and Miller, R.K.: First trimester chorionic villous explants in culture as a model to study the origin and characteristics of extravillous cytotrophoblast [abstract]. Placenta 12: 389, 1991.

    Google Scholar 

  • Genbacev, O., Schubach, S.A., and Miller, R.K.: Villous culture of first trimester human placenta—model to study extravillous trophoblast (EVT) differentiation. Placenta 13: 439–461, 1992.

    Article  PubMed  CAS  Google Scholar 

  • Genbacev, O., DeMesey Jensen, K., Schubach Powlin, S., and Miller, R.K.: In vitro differentiation and ultrastructure of human extravillous trophoblast (EVT) cells. Placenta 14: 463–475, 1993a.

    Article  PubMed  CAS  Google Scholar 

  • Genbacev, O., Gerdner, K., and Miller, R.K.: Human cytotrophoblastic cell islands from first trimester placentae—proliferative and functional activity in vitro. Placenta 14:A. 25, 1993b.

    Google Scholar 

  • Genbacev, O., White, T.E.K., Gavin, C.E., and Miller, R.K.: Human trophoblast cultures: models for implantation and peri-implantation toxicology. Reprod. Toxicol. 7: 7594, 1993c.

    Article  Google Scholar 

  • Gille, J., Börner, P., Reinecke, J., Krause, P.-H., and Deicher, H.: Über die Fibrinoidablagerungen in den Endzotten der menschlichen Placenta. Arch. Gynecol. 217: 263–271, 1974.

    CAS  Google Scholar 

  • Gladwell, P., Duncan, P., Barham, K., and Kenny, J.: Amnioscopy of late pregnancy with fetal membrane and decidual cytology. Acta Cytol. (Baltimore) 18: 333–337, 1974.

    CAS  Google Scholar 

  • Gleich, G.J., and Adolphson, C.R.: The eosinophilic leukocyte: structure and function. Adv. Immunol. 39: 177–253, 1986.

    Article  PubMed  CAS  Google Scholar 

  • Glienke, W.: Zur Ultrastruktur der Septen der menschlichen Plazenta. Z. Mikrosk. Anat. Forsch. 88: 111–147, 1974.

    PubMed  CAS  Google Scholar 

  • Globerson, A., Bauminger, S., Abel, L., and Peleg, S.: Decidual extracts suppress antibody response in vitro. Eur. J. Immunol. 6: 120–122, 1976.

    Google Scholar 

  • Golander, A., Hurley, T., Barrett, J., Handwerger, S.: Synthesis of prolactin by human decidua in vitro. J. Endocrinol. 82: 263–267, 1979.

    Article  PubMed  CAS  Google Scholar 

  • Gosseye, S., and Fox, H.: An immunohistological comparison of the secretory capacity of villous and extravillous trophoblast in the human placenta. Placenta 5: 329–348, 1984.

    Article  PubMed  CAS  Google Scholar 

  • Gossrau, R., Graf, R., Ruhnke, M., and Hanski, C.: Pro-teases in the human full-term placenta. Histochemistry 86: 405–413, 1987.

    Article  PubMed  CAS  Google Scholar 

  • Grannum, P.A.T., Berkowitz, R.L., and Hobbins, J.C.: The ultrasonic changes in the maturing placenta and their relation to fetal pulmonic maturity. Am. J. Obstet. Gynecol. 133: 915–922, 1979.

    PubMed  CAS  Google Scholar 

  • Grosser, O.: Über Fibrin und Fibrinoid in der Placenta. Z. Anat. Entwicklungsgesch. 76: 304–314, 1925.

    Article  Google Scholar 

  • Grosser, O.: Frühentwicklung, Eihautbildung und Placentation des Menschen und der Säugetiere. Bergmann, Munich, 1927.

    Google Scholar 

  • Grünwald, P.: The lobular architecture of the human placenta. Bull. John Hopkins Hosp. 119: 172–190, 1966.

    Google Scholar 

  • Grünwald, P.: Fetal deprivation and placental insufficiency. Obstet. Gynecol. 37: 906–908, 1971.

    Google Scholar 

  • Grünwald, P.: Lobular structure of hemochorial primate placentas and its relation to maternal vessels. Am. J. Anat. 136: 133–151, 1973.

    Article  Google Scholar 

  • Gu, Y., Jayatilak, P.G., Parmer, T.G., Gauldie, J., Fey, G.H., and Gibori, G.: Alpha 2-macroglobulin expression in the mesometrial decidua and its regulation by decidual luteotropin and prolactin. Endocrinology 131: 1321–1328, 1992.

    Article  PubMed  CAS  Google Scholar 

  • Gustavii, B.: Release of lysosomal acid phosphatase into the cytoplasm of decidual cells before the onset of labour in humans. Br. J. Obstet. Gynaecol. 82: 177–181, 1975.

    Article  Google Scholar 

  • Haig, D.: Genetic conflicts in human pregnancy. Q. Rev. Biol. 68: 495–532, 1993.

    Article  PubMed  CAS  Google Scholar 

  • Haller, H., Radillo, O., Rukavina, D., Tedesco, F., Candussi, G., Petrovic, O., and Randic, L.: An immunohistochemical study of leucocytes in human endometrium, first and third trimester basal decidua. J. Reprod. Immunol. 23: 41–49, 1993.

    Article  PubMed  CAS  Google Scholar 

  • Haller, U.: Beitrag zur Morphologie der UteroPlacentargefäße. Arch. Gynecol. 205: 185–202, 1968.

    CAS  Google Scholar 

  • Hamaguchi, M., Yamamoto, T., and Sugiyama, Y.: Production of prolactin by cultures of isolated cells from human first-trimester decidua. Obstet. Gynecol. 76: 783–787, 1990.

    Article  PubMed  CAS  Google Scholar 

  • Hamilton, W.J., and Boyd, J.D.: Trophoblast in human uteroplacental arteries. Nature 212: 906–908, 1966.

    Article  PubMed  CAS  Google Scholar 

  • Hamperl, H.: Über die endometrialen Granulozyten (endometriale Körnchenzellen). Klin. Wochenschr. 32: 665–668, 1954.

    Article  PubMed  CAS  Google Scholar 

  • Hansell, D.J., Bryant Greenwood, G.D., and Greenwood, F.C.: Expression of the human relaxin H1 gene in the decidua, trophoblast, and prostate. J. Clin. Endocrinol. Metab. 72: 899–904, 1991.

    Article  PubMed  CAS  Google Scholar 

  • Harman, C.R., Manning, F.A., Stearms, E., and Morrison, I.: The correlation of ultrasonic placental grading and fetal pulmonary maturation in five hundred sixty-three pregnancies. Am. J. Obstet. Gynecol. 143: 941–943, 1982.

    PubMed  CAS  Google Scholar 

  • Harris, J.W.S., and Ramsey, E.M.: The morphology of human uteroplacental vasculature. Carnegie Inst. Contrib. Embryol. 38: 43–58, 1966.

    Google Scholar 

  • Hassler, O.: Placental calcifications. Am. J. Obstet. Gynecol. 103: 348–353, 1969.

    PubMed  CAS  Google Scholar 

  • Healy, D.L., Muller, H.K., and Burger, H G • Immunofluorescence shows localisation of prolactin to human amnion. Nature 265: 642–643, 1977.

    Article  PubMed  CAS  Google Scholar 

  • Hearn, S., Walton, J., and Chapman, W.: Evidence that fibronectin in human placenta is derived from intermediate trophoblasts. Mod. Pathol. 5: 64A, 1992.

    Google Scholar 

  • Hein, K.: Licht-und elektronenmikroskopische Untersuchungen an der Basalplatte der reifen menschlichen Plazenta. Z. Zellforsch. 122: 323–349, 1971.

    Article  PubMed  CAS  Google Scholar 

  • Hellweg, G.: Über Auftreten und Verhalten der endometrialen Körnchenzellen im Verlauf der Schwangerschaft, im krankhaft veränderten Endometrium und außerhalb des Corpus Uteri. Virchows Arch. [Pathol. Anat.] 330: 658680, 1957.

    Google Scholar 

  • Hertig, A.T.: Angiogenesis in the early human chorion and in the primary placenta of the macaque monkey. Contrib. Embryol. Carnegie Inst. 25: 37–81, 1935.

    Google Scholar 

  • Hertig, A.T.: La nidation des oeufs humains fécondes normaux et anormaux. In, Les Fonctions de Nidation Uterine et Leurs Troubles. J. Ferin and M. Gaudefroy, eds., pp. 169–213. Masson, Paris, 1960.

    Google Scholar 

  • Hill, L.M., Breckle, R., Ragozzino, M.W., Wolfgram, K.R., and O’Brien, P.C.: Grade 3 placentation: incidence and neonatal outcome. Obstet. Gynecol. 61: 728–732, 1983.

    PubMed  CAS  Google Scholar 

  • Hitschmann, J., and Lindenthal, O.T.: Der weisse Infarkt der Placenta. Arch. Gynäkol. 69: 587–628, 1903.

    Article  Google Scholar 

  • Hobbins, J.C., and Winsberg, F.: Ultrasonography in Obstetrics and Gynecology. Williams and Wilkins, Baltimore, 1977.

    Google Scholar 

  • Hofmann, G.E., Scott, R.T., Jr., Bergh, P.A., and Deligdisch, L.: Immunohistochemical localization of epidermal growth factor in human endometrium, decidua, and placenta. J. Clin. Endocrinol. Metab. 73: 882–887, 1991.

    Article  PubMed  CAS  Google Scholar 

  • Hofmann, G.E., Drews, M.R., Scott, R.T., Jr., Navot, D., Heller, D., and Deligdisch, L.: Epidermal growth factor and its receptor in human implantation trophoblast: immunohistochemical evidence for autocrine/paracrine function. J. Clin. Endocrinol. Metab. 74: 981–988, 1992.

    Article  PubMed  CAS  Google Scholar 

  • Hofmann, G.E., Glatstein, I., Schatz, F., Heller, D., and Deligdisch, L.: Immunohistochemical localization of urokinase-type plasminogen activator and the plasminogen activator inhibitors 1 and 2 in early human implantation sites. Am. J. Obstet. Gynecol. 170: 671–676, 1994.

    PubMed  CAS  Google Scholar 

  • Hohn H.P., Boots, L.R., Denker, H.W., and Höök, M.: Differentiation of human trophoblast cells in vitro stimulated by extracellular matrix. Trophoblast Res. 7: 181–201, 1993.

    CAS  Google Scholar 

  • Hörmann, G.: Die Fibrinoidisierung des Chorionepithels als Konstruktionsprinzip der menschlichen Plazenta. Z. Geburtshilfe Gynäkol. 164: 263–269, 1965.

    PubMed  Google Scholar 

  • Hörmann, G.: Über die sogenannten Septen, Inseln, Zysten, Furchen and die Randzone der menschlichen Plazenta. Z. Geburtshilfe Gynäkol. 165: 125–134, 1966.

    Google Scholar 

  • Hoshina, M., Boothby, M., Hussa, R., Pattillo, R., Camel, H.M., and Boime, I.: Linkage of human chorionic gonadotrophin and placental lactogen biosynthesis to trophoblast differentiation and tumorigenesis. Placenta 6: 163–172, 1983.

    Article  Google Scholar 

  • Hoshina, M., Hussa, R., Pattillo, R., and Boime, I.: Cytologic distribution of chorionic gonadotropin subunit and placental lactogen messenger RNA in neoplasms derived from human placenta. J. Cell Biol. 97: 1200–1206, 1985.

    Article  Google Scholar 

  • Howorka, E., and Kapczynski, W.: Marginal circular haematoma disrupting the chorionic plate of the placenta. J. Obstet. Gynaecol. Br. Commonw. 78: 280–282, 1971.

    Article  PubMed  CAS  Google Scholar 

  • Hsi, B.L., and Yeh, C.J.: Monoclonal antibody GB25 recognizes human villous trophoblasts. Am. J. Reprod. Immunol. Microbiol. 12: 1–3, 1986.

    PubMed  CAS  Google Scholar 

  • Hsi, B.L., Yeh, C.J., Samson, M., and Fehlmann, M.: Monoclonal antibody GB36 raised against human trophoblast recognizes a novel epithelial antigen. Placenta 8: 209–217, 1987.

    Article  PubMed  CAS  Google Scholar 

  • Huber, C.P., Carter, J.E., and Vellios, F.: Lesions of the circulatory system of the placenta: a study of 243 placentas with special reference to the developments of infarcts. Am. J. Obstet. Gynecol. 81: 560–572, 1961.

    PubMed  CAS  Google Scholar 

  • Hui, K.Y., Haber, E., and Matsueda, G.R.: Monoclonal antibodies to a synthetic fibrin-like peptide bind to human fibrin but not to fibrinogen. Science 222: 1129–1132, 1983.

    Article  PubMed  CAS  Google Scholar 

  • Hunt, J.S.: Current topic: The role of macrophages in the uterine response to pregnancy. Placenta 11: 467–475, 1990.

    Article  PubMed  CAS  Google Scholar 

  • Hunt, J.S., Fishback, J.L., Chumbley, G., and Loke, Y.W.: Identification of class I MHC mRNA in human first trimester trophoblast cells by in situ hybridization. J. Immunol. 144: 4420–4425, 1990.

    PubMed  CAS  Google Scholar 

  • Hunt, J.S., Hsi, B.L., King, C.R., and Fishback, J.L.: Detection of class I MHC mRNA in subpopulations of first trimester cytotrophoblast cells by in situ hybridization. J. Reprod. Immunol. 19: 315–323, 1991.

    Article  PubMed  CAS  Google Scholar 

  • Hunziker, R.D., and Wegmann, T.G.: Placental Immunoregulation. Crit. Rev. Immunol. 613: 245–285, 1987.

    Google Scholar 

  • Hustin, J., and Schaaps, J.-P.: Echocardiographic and anatomic studies of the maternotrophoblastic border during the first trimester of pregnancy. Am. J. Obstet. Gynecol. 157: 162–168, 1987.

    PubMed  CAS  Google Scholar 

  • Hustin, J., and Schaaps, J.-P.: Anatomical studies of the utero-placental vascularization in the first trimester of pregnancy. Trophoblast Res. 3: 49–60, 1988.

    Google Scholar 

  • Ikkala, E., Myllylae, G., and Nevanlinna, H.R.: Transfusion therapy in factor XII (FSF) deficiency. Scand. J. Haematol. 1: 308–312, 1964.

    Article  PubMed  CAS  Google Scholar 

  • Iklé, F.A.: Dissemination von Syncytiotrophoblastzellen im mütterlichen Blut während der Gravidität. Bull. Schweiz. Akad. Med. Wiss. 20: 63–72, 1964.

    Google Scholar 

  • Ikonicoff, L.K.: Histologie et histochimie de la substance fibrinoide au niveau des villositis placentaires humaines. Rev. Fr. Gynecol. 66: 139–146, 1971.

    Google Scholar 

  • Ishizaki, Y., and Belter, L.F.: Melanin deposition in the placenta as a result of skin lesions (dermatopathic melanosis of placenta). Am. J. Obstet. Gynecol. 79: 1074–1077, 1960.

    PubMed  CAS  Google Scholar 

  • Iwanaga, S.: Ultrastructural observations on human endometrial stromal cells during the normal menstrual cycle—with special reference to so-called “predecidual cells.” Nippon Sanka Fujinka Gakkai Zasshi 35: 177–182, 1983.

    PubMed  CAS  Google Scholar 

  • Jackson, G.M., Edwin, S.S., Varer, M.W., Casal, D., and Mitchell, M.D.: Regulation of fetal fibronectin production in human chorion cells. Am. J. Obstet. Gynecol. 169: 1431 1435, 1993.

    Google Scholar 

  • Javert, C.T.: Decidual bleeding in pregnancy. Ann. N.Y. Acad. Sci. 61: 700–712, 1955.

    Article  PubMed  CAS  Google Scholar 

  • Jeacock, M.K., Scott, J., and Plester, J.A.: Calcium content of the human placenta. Am. J. Obstet. Gynecol. 87: 34–40, 1963.

    PubMed  CAS  Google Scholar 

  • Johnson, P.M., and Faulk, W.P.: Immunological studies of human placenta: identification and distribution of proteins in immature chorionic villi. Immunology 34: 1027–1036, 1978.

    PubMed  CAS  Google Scholar 

  • Kaiser, R.: Über Rückbildungsvorgaenge in der Dezidua während der Schwangerschaft. Arch. Gynecol. 192: 209220, 1960.

    Google Scholar 

  • Kanzaki, H., Crainie, M., Lin, H., Yui, J., Guilbert, L.J., Mori, T., and Wegmann, T.G.: The in situ expression of granulocyte-macrophage colony-stimulating factor (GMCSF) mRNA at the maternal-fetal interface. Growth Factors 5: 69–74, 1991.

    Article  PubMed  CAS  Google Scholar 

  • Katz, V.L., Bowes, W.A., and Sierkh, A.E.: Maternal floor infarction of the placenta associated with elevated second trimester serum alpha-fetoprotein. Am. J. Perinatol. 4: 225228, 1987.

    Google Scholar 

  • Kaufman, H., and Adams, E.: Murexide, another approach to the histochemical staining of calcium. Lab. Invest. 6: 275–280, 1957.

    PubMed  CAS  Google Scholar 

  • Kaufmann, P.: Entwicklung der Plazenta. In, Die Plazenta des Menschen. V. Becker, T.H. Schiebler, and F. Kubli, eds. Thieme, Stuttgart, 1981a.

    Google Scholar 

  • Kaufmann, P.: Fibrinoid. In, Die Plazenta des Menschen. V. Becker, T.H. Schiebler, and F. Kubli, eds. Thieme, Stuttgart, 1981b.

    Google Scholar 

  • Kaufmann, P.: Basic morphology of the fetal and maternal circuits in the human placenta. Contrib. Gynecol. Obstet. 13: 5–17, 1985.

    PubMed  CAS  Google Scholar 

  • Kaufmann, P., and Stark, J.: Die Basalplatte der reifen menschlichen Placenta. I. Semidünnschnitt-Histologie. Z. Anat. Entwicklungsgesch. 135: 1–19, 1971.

    Article  CAS  Google Scholar 

  • Kaufmann, P., and Stark, J.: Semidünnschnitt-zytochemische und immunautoradiographische Befunde zum Hormonstoffwechsel der reifen menschlichen Plazenta. Verh. Anat. Ges. 67: 245–249, 1973.

    Google Scholar 

  • Kaufmann, P., Schröder, H., and Leichtweiss, H.-P.: Fluid shift across the placenta. II. Fetomaternal transfer of horseradish peroxidase in the guinea pig. Placenta 3: 339348, 1982.

    Google Scholar 

  • Kaufmann, P., Luckhardt, T.M., and Elger, W.: The structure of the tupaia placenta. II. Ultrastructure. Anat. Embryol. (Berl.) 171: 211–221, 1985.

    Article  CAS  Google Scholar 

  • Kawagoe, K.: Immune reaction between maternal and fetal tissue at the nidatory site of tubal pregnancy. Nippon Sanka Fujinka Gakkai Zasshi 37: 2691–2696, 1985.

    PubMed  CAS  Google Scholar 

  • Kawagoe, K., Kawana, T., and Sakamoto, S.: Ultrastructure of the nidatory site in tubal pregnancy. Acta Obstet. Gynaecol. Jpn. 33: 403–410, 1981.

    CAS  Google Scholar 

  • Kawano, T., Morimoto, K., and Uemura, Y.: Urokinase inhibitor in human placenta. Nature 217: 253–254, 1968.

    Article  PubMed  CAS  Google Scholar 

  • Kazzi, G.M., Gross, T.L., and Sokol, R.J.: Fetal biparietal diameter and placental grade: predictors of intrauterine growth retardation. Obstet. Gynecol. 62: 755–759, 1983.

    PubMed  CAS  Google Scholar 

  • Kearns, M., and Lala, P.K.: Life history of decidual cells: a review. Am. J. Reprod. Immunol. 3: 78–82, 1983.

    PubMed  CAS  Google Scholar 

  • Keiffer, H.: Le placenta myometrial humain; le mechanisme de sa secretion, excretion et absorption. Arch. Biol. 38: 93108, 1928.

    Google Scholar 

  • Kephart, G.M., Andrade, Z.A., and Gleich, G.J.: Localization of eosinophil major basic protein onto eggs of Schistosoma mansoni in human pathologic tissue. Am. J. Pathol. 133: 389–396, 1988.

    PubMed  CAS  Google Scholar 

  • Khan, H., Ishihara, O., Elder, M.G., and Sullivan, M.H.: A comparison of two populations of decidual cells by immunocytochemistry and prostaglandin production. Histochemistry 96: 149–152, 1991.

    Article  PubMed  CAS  Google Scholar 

  • Khan, H., Ishihara, O., Sullivan, M.H., and Elder, M.G.: Changes in decidual stromal cell function associated with labour. Br. J. Obstet. Gynaecol. 99: 10–12, 1992.

    PubMed  CAS  Google Scholar 

  • Khong, T.Y., DeWolf, F., Robertson, W.B., and Brosens, I.: Inadequate maternal vascular response to placentation in preeclampsia and intrauterine fetal growth retardation. Br. J. Obstet. Gynaecol. 93: 1049–1059, 1986a.

    Article  PubMed  CAS  Google Scholar 

  • Khong, T.Y., Lane, E.B., and Robertson, W.B.: An immunocytochemical study of fetal cells at the maternal-placental interface using monoclfonal antibodies to keratins, vimentin and desmin. Cell Tissue Res. 246: 189–195, 1986b.

    Article  PubMed  CAS  Google Scholar 

  • Khudr, G., Soma, H., and Benirschke, K.: Trophoblastic origin of the X-cell and the placental giant cell. Am. J. Obstet. Gynecol. 115: 530–533, 1973.

    PubMed  CAS  Google Scholar 

  • Kim, C.K., and Benirschke, K.: Autoradiographic study of the “X-cells” in the human placenta. Am. J. Obstet. Gynecol. 109: 96–102, 1971.

    PubMed  CAS  Google Scholar 

  • Kim, C.K., Altshuler, G.P., and Benirschke, K.: Karyotypic analysis of the X-cell in the human placenta. Obstet. Gynecol. 37: 72–82, 1971a.

    PubMed  CAS  Google Scholar 

  • Kim, C.K., Naftolin, F., and Benirschke, K.: Immunohistochemical studies of the “X-cell” in the human placenta with anti-human chorionic gonadotropin and anti-human placental lactogen. Am. J. Obstet. Gynecol. 111: 672–676, 1971b.

    PubMed  CAS  Google Scholar 

  • King, A., and Loke, Y.W.: Differential expression of bloodgroup-related carbohydrate antigens by trophoblast sub-populations. Placenta 9: 513–521, 1988.

    Article  PubMed  CAS  Google Scholar 

  • King, A., and Loke, Y.W.: Uterine large granular lymphocytes: a possible role in embryo implantation ? Am. J. Obstet. Gynecol. 162: 308–310, 1990.

    PubMed  CAS  Google Scholar 

  • King, A., and Loke, Y.W.: On the nature and function of human uterine granular lymphocytes. Immunol. Today 12: 432–435, 1991.

    Article  PubMed  CAS  Google Scholar 

  • King, A., Birkby, C., and Loke, Y.W.: Early human decidual cells exhibit NK activity against the K562 cell line but not against first trimester trophoblast. Cell. Immunol. 118: 337344, 1989.

    Google Scholar 

  • King, A., Kalra, P., and Loke, Y.W.: Human trophoblast cell resistance to decidual NK lysis is due to lack of NK target structure. Cell. Immunol. 127: 230–237, 1990.

    Article  PubMed  CAS  Google Scholar 

  • King, B.F., and Blankenship, T.N.: Expression of proliferating cell nuclear antigen (PCNA) in developing macaque placentas. Placenta 14:A. 36, 1993.

    Google Scholar 

  • Kirby, D.R.S., Billington, W.D., Bradbury, S., and Goldstein, D.J.: Antigen barrier of mouse placenta. Nature 204: 548–549, 1964.

    Article  PubMed  CAS  Google Scholar 

  • Kirkinen, P., and Jouppila, P.: Intrauterine membranous cyst: a report of antenatal diagnosis and obstetric aspects in two cases. Obstet. Gynecol. 67: 26S - 30S, 1986.

    Article  PubMed  CAS  Google Scholar 

  • Kisalus, L.L., and Herr, J.C.: Immunocytochemical localization of heparan sulfate proteoglycan in human decidual cell secretory bodies and placental fibrinoid. Biol. Reprod. 39: 419–430, 1988.

    Article  PubMed  CAS  Google Scholar 

  • Kisalus, L.L., Herr, J.C., and Little, C.D.: Immunolocalization of extracellular matrix proteins and collagen synthesis in first trimester human decidua. Anat. Rec. 218: 402–415, 1987.

    Article  PubMed  CAS  Google Scholar 

  • Klein, G.: Makroskopisches Verhalten der UteroPlacentargefässe. In, Die menschliche Placenta. Beiträge zur normalen und pathologischen Anatomie derselben. Hofmeier, ed., pp. 72–87. Bergmann, Wiesbaden, 1890.

    Google Scholar 

  • Kliman, H.J., and Feinberg, R.F.: Human trophoblastextracellular matrix (ECM) interactions in vitro: ECM thickness modulates morphology and proteolytic activity. Proc. Natl. Acad. Sci. U.S.A. 87: 3057–3061, 1990.

    Article  PubMed  CAS  Google Scholar 

  • Kliman, H.J., Nestler, J.E., Sermasi, E., Sanger, J.M., and Strauss, J.F., III: Purification, characterization, and in vitro differentiation of cytotrophoblasts from human term placentae. Endocrinology 118: 1567–1582, 1985.

    Article  Google Scholar 

  • Kliman, H.J., Feinman, M.A., and Strauss, J.F., III: Differentiation of human cytotrophoblasts into syncytiotrophoblasts in culture. Trophoblast Res. 2: 407–421, 1987.

    Google Scholar 

  • Kliman, H.J., Feinberg, R.F., and Haimowitz, J.E.: Human trophoblast-endometrial interactions in an in vitro suspension culture system. Placenta 11: 349–367, 1990.

    Article  PubMed  CAS  Google Scholar 

  • Klinger, H.P.: The sex chromatin in fetal and maternal portions of the human placenta. Acta Anat. (Basel) 30: 371–397, 1957.

    CAS  Google Scholar 

  • Klinger, H.P., and Ludwig, K.S.: Sind die Septen und die grosszelligen Inseln der Placenta aus mütterlichem oder kindlichem Gewebe aufgebaut? Z. Anat. Entwicklungsgesch. 120: 95–100, 1957.

    Article  CAS  Google Scholar 

  • Klopper, H.: The new placental proteins. Placenta 1: 77–89, 1980.

    Article  PubMed  CAS  Google Scholar 

  • Kölliker, A.: Entwicklungsgeschichte des Menschen und der höheren Thiere. 1st Ed. Engelmann, Leipzig, 1861.

    Google Scholar 

  • Kölliker, A.: Entwicklungsgeschichte des Menschen und der höheren Thiere. 2nd Ed. Engelmann, Leipzig, 1879.

    Book  Google Scholar 

  • Kohnen, G., Kosanke, G., Korr, H., and Kaufmann, P.: Comparison of various proliferation markers applied to human placental tissue. Placenta 14: A38, 1993.

    Google Scholar 

  • Korhonen, M., Ylanne, J., Laitinen, L., Cooper, H.M., Quaranta, V., and Virtanen, I.: Distribution of the alpha 1-alpha 6 integrin subunits in human developing and term placenta. Lab. Invest. 65: 347–356, 1991.

    PubMed  CAS  Google Scholar 

  • Kosanke, G.: Methodological studies of proliferation markers applied to human placental villi. Biology doctoral thesis, Sciences Faculty, Technical University of Aachen, 1994.

    Google Scholar 

  • Kottsova, N.A., Bystrova, O.A., Susloparov, L.A., and Mikhailov, V.M.: Changes in the cellular composition of the deciduous membrane in physiologic pregnancy and late toxicosis. Arkh. Anat. Gistol. Embriol. 97: 76–82, 1989.

    PubMed  CAS  Google Scholar 

  • Krafft, M.-L.: Über den Halte-und Verspannungsapparat der plazentaren Randzone und der Eihäute. (Nach graphischen Rekonstruktionen.) Inaugural dissertation, Berlin, 1973.

    Google Scholar 

  • Kratzsch, E., and Grygiel, I.-H.: Über das Vorkommen eines spezifischen Enzyms der Glucuronsäurebildung im menschlichen Amnion. Z. Zellforsch. 123: 566–571, 1972.

    Article  PubMed  CAS  Google Scholar 

  • Kretschmann, H.-J.: Über Feinstruktur des subchorialen Placentarfibrins im Vergleich mit der des Blutfibrins. I. Orthoskopische Analyse. Acta Anat. (Basel) 66: 339–364, 1967a.

    CAS  Google Scholar 

  • Kretschmann, H.-J.: Über die Feinstruktur des subchorialen Placentarfibrins im Vergleich mit der des Blutfibrins. II. Experimentelle Studie Über Veränderungen der Feinstruktur des Blutfibrins. Acta Anat. (Basel) 66: 494503, 1967b.

    Google Scholar 

  • Krönicher, W.D.: Ein Beitrag zur Genese der Inseln in der menschlichen Placenta. Z. Mikrosk. Anat. Forsch. 89: 777803, 1975.

    Google Scholar 

  • Krohn, K., Ljungqvist, A., and Robertson, B.: Trophoblastic and subtrophoblastic mineral salt deposition in hydramnios. Acta Pathol. Microbiol. Scand. 69: 514–520. 1967.

    Article  CAS  Google Scholar 

  • Kubli, F.: Die chronische Placentarinsuffizienz. Gynakologe 1: 53–60, 1968.

    Google Scholar 

  • Kubota, T., Kamada, S., Hirata, Y., Eguchi, S., Imai, T., Marumo, F., and Aso, T.: Synthesis and release of endothelin-1 by human decidual cells. J. Clin. Endocrinol. Metab. 75: 1230–1234, 1992.

    Article  PubMed  CAS  Google Scholar 

  • Kühler, W.: Die Deciduaverteilung in der menschlichen Placenta. Inaugural dissertation, Wesel, pp. 1–38, 1890. Kunicki, T.J., Nugent, D.J., Staats, S.J., Orchekowski, R.P., Wayner E.A., and Carter W.G.: The human fibroblast class II extracellular matrix receptor mediates platelet adhesion to collagen and is identical to the platelet la-IIa complex. J. Biol. Chem. 263: 4516–4519, 1988.

    Google Scholar 

  • Kurman, R.J., Main, C.S., and Chen, H.C.: Intermediate trophoblast: a distinctive form of trophoblast with specific morphological, biochemical and functional features. Placenta 5: 349–369, 1984a.

    Article  PubMed  CAS  Google Scholar 

  • Kurman, R.J., Young, R.H., Norris, H.J., Main, C.S., Lawrence, W.D., and Sculley, R.E.: Immunocytochemical localization of placental lactogen and chorionic gonadotropin in the normal placenta and trophoblastic tumors, with emphasis on intermediate trophoblast and the placental site trophoblastic tumor. Int. J. Gynecol. Pathol. 3: 101121, 1984b.

    Google Scholar 

  • Kyodo, Y., Kobayashi, T., and Terao, T.: Studies on the immunohistochemical localization of coagulation fibrinolysis factors in the placenta, especially of placental plasminogen activator (PPA). Nippon Sanka Fujinka Gakkai Zasshi 38: 10–16, 1986.

    PubMed  CAS  Google Scholar 

  • Ladines Llave, C.A., Maruo, T., Manalo, A.M., and Mochizuki, M.: Decreased expression of epidermal growth factor and its receptor in the malignant transformation of trophoblasts. Cancer 71: 4118–4123, 1993.

    Article  Google Scholar 

  • Lala, P.K., Kearns, M., and Colavincenzo, V.: Cells of the fetomaternal interface: their role in the maintenance of viviparous pregnancy. Am. J. Anat. 170: 501–517, 1984.

    Article  PubMed  CAS  Google Scholar 

  • Lala, P.K., Kearns, M., and Pahar, R.S.: Immunobiology of the decidual tissue: the maternal component of the fetomaternal interface. In, Immunoregulation and Fetal Survival. T. Gill and T.G. Wegmann, eds. Oxford University Press, New York, 1985.

    Google Scholar 

  • Lang, I., Hartmann, M., Blaschitz, A., Dohr, G., Skofitsch, G., and Desoye, G.: Immunohistochemical evidence for the heterogeneity of maternal and fetal vascular endothelial cells in human full-term placenta. Cell Tissue Res. 274: 21 1218, 1993.

    Google Scholar 

  • Lang, I., Hartmann, M., Blaschitz, A., Dohr, G., Kaufmann, P., Frank, H.G., Hahn, T., Skofitsch, G., and Desoye, G.: Differential lectin binding to the fibrinoid of human full term placenta: correlation with a fibrin antibody and the PAF-Halmi method. Acta Anat. (Basel) 1994 (in press).

    Google Scholar 

  • Langhans, T.: Untersuchungen über die menschliche Placenta. Arch. Anat. Physiol., Anat. Abt. 188–267, 1877.

    Google Scholar 

  • Lapan, B., and Friedman, M.M.: Tissue enzymes in gestation: comparative activities in the placenta and fetal membranes. Am. J. Obstet. Gynecol. 93: 1157–1163, 1965.

    PubMed  CAS  Google Scholar 

  • Larsen, J.F., and Knoth, M.: Ultrastructure of the anchoring villi and trophoblastic shell in the second week of placentation. Acta Obstet. Gynecol. Scand. 50: 117–128, 1971.

    Article  CAS  Google Scholar 

  • Larsen, L.G., Theilade, K., Skibsted, L., and Jacobsen, G.K.: Malignant placental site trophoblastic tumor: a case report and a review of the literature. APMIS Suppl. 23: 138–145, 1991.

    PubMed  CAS  Google Scholar 

  • Latta, J.S., and Beber, C.R.: The differentiation of a special form of trophoblast in the human placenta. Am. J. Obstet. Gynecol. 74: 105–110, 1957.

    PubMed  CAS  Google Scholar 

  • Lawn, A.M., Wilson, E.W., and Finn, C.A.: The ultra-structure of human decidual and predecidual cells. J. Reprod. Fertil. 26: 85–90, 1971.

    Article  PubMed  CAS  Google Scholar 

  • Leivo, I., Laurila, P., Wahlstrom, T., and Engvall, E.: Expression of merosin, a tissue-specific basement membrane protein, in the intermediate trophoblast cells of choriocarcinoma and placenta. Lab. Invest. 60: 783–790, 1989.

    PubMed  CAS  Google Scholar 

  • Librach, C.L., Werb, Z., Fitzgerald, M.L., Chiu, K., Corwin, N.M., Esteves, R.A., Grobelny, D., Galardy, R., Damsky, C.H., and Fisher, S.J.: 92-kD Type IV collagenase mediates invasion of human cytotrophoblasts. J. Cell Biol. 113: 437449, 1991.

    Google Scholar 

  • Liotta, L.A., Steeg, P.S., and Stetler-Stevenson, W.G.: Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation. Cell 64: 327–336, 1991.

    Article  PubMed  CAS  Google Scholar 

  • Linthwaite, R. F.: Subchorial hematoma mole (Breus’ mole). J.A.M.A. 186: 867–870, 1963.

    Article  PubMed  CAS  Google Scholar 

  • Logothetou Relia, H., Kotoulas, I.G., Nesland, J.M., Kipiotis, D., and Abazis, D.: Early human trophoblast cell cultures: a morphological and immunocytochemical study. Histol. Histopathol. 4: 367–374, 1989.

    Google Scholar 

  • Loke, Y.W.: Trophoblast antigen expression. Curr. Opin. Immunol. 1: 1131–1134, 1989.

    Article  PubMed  CAS  Google Scholar 

  • Loke, Y.W.: Experimenting with human extravillous trophoblast: a personal view. Am. J. Reprod. Immunol. 24: 22–28, 1990.

    PubMed  CAS  Google Scholar 

  • Loke, Y.W., and Day, S.: Monoclonal antibody to human cytotrophoblast. Am. J. Reprod. Immunol. 5: 106–108, 1984.

    PubMed  CAS  Google Scholar 

  • Loke, Y.W., and King, A.: Recent developments in the human maternal-fetal immune interaction. Curr. Opin. Immunol. 3: 762–766, 1991.

    Article  PubMed  CAS  Google Scholar 

  • Loke, Y.W., Butterworth, B.H., Margetts, J.J., and Burland, K.: Identification of cytotrophoblast colonies in cultures of human placental cells using monoclonal antibodies. Placenta 7: 221–231, 1986.

    Article  PubMed  CAS  Google Scholar 

  • Loke, Y.W., and Burland, K.: Human trophoblast cells cultured in modified medium and supported by extracellular matrix. Placenta 9: 173–182, 1988.

    Article  PubMed  CAS  Google Scholar 

  • Loke, Y.W., Gardner, L., and Grabowska, A.: Isolation of human extravillous trophoblast cells by attachment to laminin-coated magnetic beads. Placenta 10: 407–415, 1989a.

    Article  PubMed  CAS  Google Scholar 

  • Loke, Y.W., Gardner, L., Burland, K., and King, A.: Laminin in human trophoblast—decidua interaction. Hum. Reprod. 4: 457–463, 1989b.

    PubMed  CAS  Google Scholar 

  • Loke, Y.W., Hsi, B.L., Bulmer, J.N., Grivaux, C., Hawley, S., Gardner, L., King, A., and Carter, N.P.: Evaluation of a monoclonal antibody, BC-1, which identifies an antigen expressed on the surface membrane of human extravillous trophoblast. Am. J. Reprod. Immunol. 27: 77–81, 1992a.

    PubMed  CAS  Google Scholar 

  • Loke, Y.W., King, A., Gardner, L., and Carter, N.P.: Evidence for the expression of granulocyte-macrophage colony-stimulating factor receptors by human first trimester extravillous trophoblast and its response to this cytokine. J. Reprod. Immunol. 22: 33–45, 1992b.

    Article  PubMed  CAS  Google Scholar 

  • Luckett, W.P.: Origin and differentiation of the yolk sac and extraembryonic mesoderm in presomite human and rhesus monkey embryos. Am. J. Anat. 152: 59–97, 1978.

    Article  PubMed  CAS  Google Scholar 

  • Ludwig, K.S.: Die Rolle des Fibrins bei der Bildung der menschlichen Placenta. Acta Anat. (Basel) 38: 323–331, 1959.

    CAS  Google Scholar 

  • Ludwig, K.S.: Zur Feinstruktur der materno-fetalen Verbindung im Plazentom des Schafes (Ovis aries L.). Experientia 18: 212, 1962.

    Article  PubMed  CAS  Google Scholar 

  • Ludwig, H., and Metzger, H.: Das uterine Placentarbett post partum im Rasterelektronenmikroskop, zugleich ein Beitrag zur Frage der extravasalen Fibrinbildung. Arch. Gynecol. 210: 251–266, 1971.

    CAS  Google Scholar 

  • Lysiak, J., Khoo, N., Conelly, I., Stettler-Stevenson, W., and Peeyush, L.: Role of transforming growth factor (TGF) a and epidermal growth factor (EGF) on proliferation, invasion, and hCG production by normal and malignant trophoblast. Placenta 13: A41, 1992.

    Article  Google Scholar 

  • Maddox, D.E., Butterfield, J.H., Ackerman, S.J., Coulam, C.B., and Gleich, G.J.: Elevated serum levels in human pregnancy of a molecule immunochemically similar to eosinophil granule major basic protein. J. Exp. Med. 158: 1211–1226, 1983.

    Article  PubMed  CAS  Google Scholar 

  • Maddox, D.E., Kephart, G.M., Coulam, C.B., Butterfield, J.H., Benirschke, K., and Gleich, G.J.: Localization of a molecule immunochemically similar to eosinophil major basic protein in human placenta. J. Exp. Med. 160: 29–41, 1984.

    Article  PubMed  CAS  Google Scholar 

  • Maidman, J.E., Thorpe, L.W., Harris, J.A., and Wynn, R.M.: Fetal origin of X-cells in human placental septa and basal plate. Obstet. Gynecol. 41: 547–552, 1973.

    PubMed  CAS  Google Scholar 

  • Malak, T.M., Ockleford, C.D., Bell, S.C., Dalgleish, R., Bright, N., and MacVicar, J.: Confocal immunofluorescence localization of collagen type-I, type-III, type-IV, type-V and type-VI and their ultrastructural organization in term human fetal membranes. Placenta 14: 385–406, 1993.

    Article  PubMed  CAS  Google Scholar 

  • Manaseki, S., and Searle, R.F.: Natural killer (NK) cell activity of first trimester human decidua. Cell. Immunol. 121: 166–173, 1989.

    Article  PubMed  CAS  Google Scholar 

  • Manivel, J.C., Niehans, G., Wick, M.R., and Dehner, L.P.: Intermediate trophoblast in germ cell neoplasms. Am. J. Surg. Pathol. 11: 693–701, 1987.

    Article  PubMed  CAS  Google Scholar 

  • Mansager, N., Bendon, R., Rosenn, B., Miodovnik, M., Mostello, D., and Siddiqi, T.A.: Maternal floor infarction: prenatal diagnosis and clinical significance [abstract 170]. Am. J. Obstet. Gynecol. 168: 347, 1993.

    Google Scholar 

  • Marais, W.D.: Human decidual spiral artery studies. I. Anatomy, circulation and pathology of the placenta. observations with a colposcope. J. Obstet. Gynaecol. Br. Commonw. 69: 1–122, 1962.

    Article  CAS  Google Scholar 

  • Martinek, J.J.: Fibrinoid and the fetal-maternal interface of the rat placenta. Anat. Rec. 166: 587–604, 1970.

    Article  PubMed  CAS  Google Scholar 

  • Martinek, J.J.: Ultrastructure of the deciduotrophoblastic interface of the mouse placenta. Am. J. Obstet. Gynecol. 109: 424–431, 1971.

    PubMed  CAS  Google Scholar 

  • Matsuo, H., Maruo, T., Murata, K., and Mochizuki, M.: Human early placental trophoblasts produce an epidermal growth factor-like substance in synergy with thyroid hormone. Acta Endocrinol. (Copenh.) 128: 225–229, 1993.

    CAS  Google Scholar 

  • Mau, G., and Netter, P.: Blutungen in der Frühschwangerschaft: ein Hinweis auf kindliche Mißbildungen? Z. Kinderheilk. 117: 79–88, 1974.

    Article  CAS  Google Scholar 

  • McCombs, H.L., and Craig, J.M.: Decidual necrosis in normal pregnancy. Obstet. Gynecol. 24: 436–442, 1964.

    PubMed  CAS  Google Scholar 

  • McCormick, J.N., Faulk, W.P., Fox, H., and Fudenberg, H.H.: Immunohistological and elution studies of the human placenta. J. Exp. Med. 91: 1–13, 1971.

    Article  Google Scholar 

  • McKay, D.G., Hertig, A.T., Adams, E.C., and Richardson, M.V.: Histochemical observations on the human placenta. Obstet. Gynecol. 12: 1–36, 1958.

    Article  PubMed  CAS  Google Scholar 

  • McWey, L.A., Singhas, C.A., and Rogol, A.D.: Prolactin binding sites on human chorion-decidua tissue. Am. J. Obstet. Gynecol. 144: 283–288, 1982.

    PubMed  CAS  Google Scholar 

  • Moe, N.: Deposits of fibrin and plasma proteins in the normal human placenta. Acta Pathol. Microbiol. Scand. 76: 74–88, 1969a.

    Article  CAS  Google Scholar 

  • Moe, N.: Histological and histochemical study of the extracellular deposits in the normal human placenta. Acta Pathol. Microbiol. Scand. 76: 419–431, 1969b.

    Article  CAS  Google Scholar 

  • Moe, N.: The cytotrophoblastic cell columns and the cell islands of the normal human placenta. Acta Pathol. Microbiol. Scand. 76: 401–418, 1969c.

    Article  CAS  Google Scholar 

  • Moe, N.: The deposits of fibrin and fibrin-like materials in the basal plate of the normal human placenta. Acta Pathol. Microbiol. Scand. 75: 1–17, 1969d.

    CAS  Google Scholar 

  • Moll, U.M., and Lane, B.L.: Proteolytic activity of first trimester human placenta: localization of interstitial collagenase in villous and extravillous trophoblast. Histochemistry 94: 555–560, 1990.

    Article  PubMed  CAS  Google Scholar 

  • Moll, W., Nienartowicz, A., Hees, H., Wrobel, K.-H., and Lenz, A.: Blood flow regulation in the uteroplacental arteries. Trophoblast Res. 3: 83–96, 1988.

    Google Scholar 

  • Monaghan, J., O’Herlihy, C., and Boylan, P.: Ultrasound placental grading and amniotic fluid quantitation in prolonged pregnancy. Obstet. Gynecol. 70: 349–352, 1987.

    PubMed  CAS  Google Scholar 

  • Montemagno, U.: La sostanza fibrinoide placentare. Arch. Ostetr. Ginecol. (Napoli) 72: 585–596, 1967.

    CAS  Google Scholar 

  • Morris, N.H., Eaton, B.M., Sooranna, S.R., and Steer, P.J.: NO synthase activity in placental bed and tissues from normotensive pregnant women. Lancet 342: 679–680, 1993.

    Article  PubMed  CAS  Google Scholar 

  • Mortimer, G., Mackay, M.M., and Stimson, W.H.: The distribution of pregnancy-associated prostaglandin synthetase inhibitor in the human placenta. J. Pathol. 159: 239–243, 1989.

    Article  PubMed  CAS  Google Scholar 

  • Mossman, H.W.: Comparative morphogenesis of the foetal membranes and accessory uterine structures. Contrib. Embryol. Carnegie Inst. 26: 129–246, 1937.

    Google Scholar 

  • Mossman, H.W.: Vertebrate Fetal Membranes: Comparative Ontogeny and Morphology; Evolution; Phylogenetic Significance; Basic Functions; Research Opportunities. Macmillan, London, 1987.

    Google Scholar 

  • Mühlhauser, J., Crescimanno, C., Kaufmann, P., Höfler, H., Zaccheo, D., and Castellucci, M.: Differentiation and proliferation patterns in human trophoblast revealed by cerbB-2 oncogene product and EGF-R. J. Histochem. Cytochem. 41: 165–173, 1993.

    Article  PubMed  Google Scholar 

  • Naeye, R.L.: Maternal floor infarction. Hum. Pathol. 16: 823828, 1985.

    Google Scholar 

  • Nanaev, A.K., Milovanov, A.P., and Domogatsky, S.P.: Immunohistochemical localization of extracellular matrix in perivillous fibrinoid of normal human term placenta. Histochemistry 100: 341–346, 1993a.

    Article  PubMed  CAS  Google Scholar 

  • Nanaev, A.K., Milovanov, A.P., and Domogatsky, S.P.; Immunohistochemical localization of extracellular matrix in various types of fibrinoid of the normal human term placenta. Placenta 14:A. 55, 1993b.

    Google Scholar 

  • Nelson, D.M., Crouch, E.C., Curran, E.M., and Farmer, D.R.: Trophoblast interaction with fibrin matrix. Epithelialization of perivillous fibrin deposits as a mechanism for villous repair in the human placenta. Am. J. Pathol. 136: 855–865, 1990.

    PubMed  CAS  Google Scholar 

  • Neuberg, M.: Decidual prolactin. Wiad. Lek. 45: 376–380, 1992.

    PubMed  CAS  Google Scholar 

  • Neumann, E.: Die Picrocarminfärbung und ihre Anwendung auf die Entzündungslehre. Arch. Mikrosk. Anat. 18: 130150, 1880.

    Google Scholar 

  • Nickel, R.E.: Maternal floor infarction: an unusual cause of intrauterine growth retardation. Am. J. Dis. Child. 142: 1270–1271, 1988.

    PubMed  CAS  Google Scholar 

  • Nikolov, S.D., and Schiebler, T.H.: Über die Gefässe der Basalplatte der reifen menschlichen Placenta. Licht-und elektronenmikroskopische Untersuchungen. Z. Zellforsch. 139: 319–332, 1973.

    Article  PubMed  CAS  Google Scholar 

  • Nitabuch, R.: Beiträge zur Kenntnis der menschlichen Plazenta. Inaugural dissertation, Stämpfli, Bern, 1887.

    Google Scholar 

  • Ockleford, C.D., Malak, T., Hubbard, A., Bracken, K., Burton, S.A., Bright, N., Blakey, G., Goodliffe, J., Garrod, D., and d’Lacey, C.: Human amniochorion cytoskeletons at term. Placenta 14: A56, 1993.

    Article  Google Scholar 

  • Ockleford, C., Bright, N., Hubbard, A., d’Lacey, C., Smith, J., Gardiner, L., Sheikh, T., Albentosa, M., and Turtle, K.: Micro-trabeculae, macro-plaques or mini-basement membranes in human term fetal membranes. Philos. Trans. R. Soc. Lond. [Biol.] 342: 121–136, 1994.

    Article  Google Scholar 

  • O’Connor, D.M., and Kurman, R.J.: Intermediate trophoblast in uterine curettings in the diagnosis of ectopic pregnancy. Obstet. Gynecol. 72: 665–670, 1988a.

    PubMed  Google Scholar 

  • O’Connor, D.M., and Kurman, R.J.: Utilization of intermediate trophoblast in the diagnosis of an in utero gestation in endometrial curettings without chorionic villi. Mod. Pathol. 1: 68A, 1988b.

    Google Scholar 

  • Okudaira, Y., Hashimoto, T., Hamanaka, N., and Yoshinare, S.: Electron microscopic study on the trophoblastic cell column of human placenta. J. Electron Microsc. 20: 93–106, 1971.

    CAS  Google Scholar 

  • Okudaira, Y., Matsui, Y., and Kanoh, H.: Morphological variability of human trophoblasts in normal and neoplastic conditions—an ultrastructural reappraisal. In, Placenta: Basic Research for Clinical Application. H. Soma, ed. Karger, Basel, 1991.

    Google Scholar 

  • Olâh, C.S., Gee, H., Rushton, I., and Fowlie, A.: Massive subchorionic thrombohaematoma presenting as a placental tumour: case report. Br. J. Obstet. Gynaecol. 94: 995–997, 1987.

    Article  PubMed  Google Scholar 

  • Ono, H., Ide, C., and Nishiya, I.: Electron microscopic study on early decidualization of the endometrium of pregnant mice, with special reference to gap junctions. Placenta 10: 247–261, 1989.

    Article  PubMed  CAS  Google Scholar 

  • Ornoy, A., Benady, S., Kohen-Raz, R., and Russell, A.: Association between maternal bleeding during gestation and congenital anomalies in the offspring. Am. J. Obstet. Gynecol. 124: 474–478, 1976.

    PubMed  CAS  Google Scholar 

  • Ortmann, R.: Histochemische Untersuchungen an menschlicher Plazenta mit besonderer Berücksichtigung der Kernkugeln (Kerneinschlüsse) und der Plasmalipoideinschlüsse. Z. Anat. Entwicklungsgesch. 119: 28–55, 1955.

    Article  PubMed  CAS  Google Scholar 

  • Ortmann, R.: Morphologie der menschlichen Placenta. Anat. Anz. 106 /107: 27–56, 1960.

    Google Scholar 

  • Oswald, B., and Gerl, D.: Die Mikrofibrinoidablagerungen in der menschlichen Placenta. Acta Histochem. 42: 356–359, 1972.

    PubMed  CAS  Google Scholar 

  • Pace, D., Morrison, L., and Bulmer, J.N.: Proliferative activity in endometrial stromal granulocytes throughout menstrual cycle and early pregnancy. J. Clin. Pathol. 42: 35–39, 1989.

    Article  PubMed  CAS  Google Scholar 

  • Paddock, R., and Greer, E.D.: Origin of common cystic structure of human placenta. Am. J. Obstet. Gynecol. 13: 164–173, 1927.

    Google Scholar 

  • Padykula, H.A., and Driscoll, S.G.: Decidual cell differentiation in the normal early gestational uterus includes lymphoid infiltration. Anat. Rec. 190: 500–501, 1978.

    Google Scholar 

  • Pampfer, S., Daiter, E., Barad, D., and Pollard, J.W.: Expression of the colony-stimulating factor-1 receptor (cfms proto-oncogene product) in the human uterus and placenta. Biol. Reprod. 46: 48–57, 1992.

    Article  PubMed  CAS  Google Scholar 

  • Panigel, M., and Pascaud, M.: Les orifices artériels d’entrée du sang maternel dans la chambre intervilleuse du placenta humain. Bull. Assoc. Anat. 53rd Congres (Tours. No. 142 ), pp. 1287–1298, 1968.

    Google Scholar 

  • Parhar, R.S., Yagel, S., and Lala, P.K.: PGE2—mediated immunosuppression by first trimester human decidual cells blocks activation of maternal leukocytes in the decidua with potential anti-trophoblast activity. Cell Immunol. 120: 6174, 1989.

    Article  Google Scholar 

  • Park, W.W.: Disorders arising from the human trophoblast. In, Modern Trends in Pathology. D.H. Collins, ed., pp. 180–211. Butterworth, London, 1959.

    Google Scholar 

  • Parmley, T.H., Gupta, P.K., and Walker, M.A.: “Aging” pigments in term human placenta. Am. J. Obstet. Gynecol. 139: 760–766, 1981.

    PubMed  CAS  Google Scholar 

  • Peel, S., and Bulmer, D.: The fine structure of the rat metrial gland in relation to the origin of the granulated cells. J. Anat. 123: 687–969, 1977.

    PubMed  CAS  Google Scholar 

  • Perrin, E.V.D.K.: Placenta as a reflection of fetal disease: a brief overview. In, Pathology of the Placenta. E.V.D.K. Perrin, ed. Churchill Livingstone, New York, 1984.

    Google Scholar 

  • Petraglia, F., Sawchenko, P., Lim, A.T.W., Rivier, J., and Vale, W.: Localization, secretion, and action of inhibin in human placenta. Science 237: 187–189, 1987.

    Article  PubMed  CAS  Google Scholar 

  • Petrucha, R.A., and Platt, L.D.: Relationship of placental grade to gestational age. Am. J. Obstet. Gynecol. 144: 733735, 1982.

    Google Scholar 

  • Petry, G.: Der Bau der menschlichen Eihaut und seine funk- tionelle Bedeutung. Klin. Wochenschr. 32: 1020, 1954a.

    Google Scholar 

  • Petry, G.: Studien über die morphologischen Grundlagen des Blasensprungs. Zentralbl. Gynäkol. 76:655— 675, 1954b.

    Google Scholar 

  • Pfeiffer, R.A.: Nanisme microcephalique letal: exemple de pathologie placentaire d’origine genetique ? J. Genet. Hum. 22: 259–261, 1974.

    PubMed  CAS  Google Scholar 

  • Pijnenborg, R., Dixon, G., Robertson, W.B., and Brosens, I.: Trophoblastic invasion of human decidua from 8 to 18 weeks of pregnancy. Placenta 1: 3–19, 1980.

    Article  PubMed  CAS  Google Scholar 

  • Pijnenborg, R., Robertson, W.B., Brosens, I., and Dixon, G.: Trophoblast invasion and the establishment of haemochorial placentation in man and laboratory animals. Placenta 2: 71–92, 1981.

    Article  PubMed  CAS  Google Scholar 

  • Piotrowicz, R.S., Orchekowski, D.J., Nugent, D.J., Yamada, K.Y., and Kunicki T.J.: Glycoprotein le-IIa functions as an activation-independent fibronectin receptor on human platelets. J. Cell Biol. 106: 1359–1364, 1988.

    Article  PubMed  CAS  Google Scholar 

  • Pitkin, R.M.: Calcium metabolism in pregnancy: a review. Am. J. Obstet. Gynecol. 121: 724–737, 1975.

    PubMed  CAS  Google Scholar 

  • Pitkin, R.M., Reeynolds, W.A., Williams, G.A., and Hargis, G.K.: Calcium metabolism in normal pregnancy: a longitudinal study. Am. J. Obstet. Gynecol. 133: 781–790, 1979.

    PubMed  CAS  Google Scholar 

  • Powell, H.C., Benirschke, K., Favara, B.E., and Pflueger, O.H.: Foamy changes of placental cells in fetal storage disorders. Virchows Arch. [A] 369: 191–196, 1976.

    CAS  Google Scholar 

  • Pozniak, M.A., Cullenward, M.J., Zickuhr, D., and Curet, L.B.: Venous lake bleeding: a complication of chorionic villus sampling. J. Ultrasound Med. 7: 297–299, 1988.

    PubMed  CAS  Google Scholar 

  • Raghupathy, R., Singh, B., Barrington-Leigh, J., and Wegmann, T.G.: The ontogeny and turnover kinetics of paternal H-2 K antigenic determinants on the allogenic murine placenta. J. Immunol. 127: 2074, 1981.

    PubMed  CAS  Google Scholar 

  • Raghupathy, R., Singh, B., and Wegmann, T.G.: Fate of antipaternal H-2 antibodies bound to the placenta in vivo. Transplantation 37: 296, 1984.

    Article  PubMed  CAS  Google Scholar 

  • Ramsey, E.M.: Circulation in the maternal placenta of the rhesus monkey and man, with observations on the marginal lakes. Am. J. Anat. 98: 159–190, 1956.

    Article  PubMed  CAS  Google Scholar 

  • Ramsey, E.M.: Circulation in the intervillous space of the primate placenta. Am. J. Obstet. Gynecol. 84: 1649–1663, 1962.

    PubMed  CAS  Google Scholar 

  • Ramsey, E.M.: The story of the spiral arteries. J. Reprod. Med. 26: 393–399, 1981.

    PubMed  CAS  Google Scholar 

  • Ramsey, E.M., and Donner, M.W.: Placental Vasculature and Circulation. Thieme, Stuttgart, 1980.

    Google Scholar 

  • Ramsey, E.M., and Harris, J.W.S.: Comparison of uteroplacental vasculature and circulation in the rhesus monkey and man. Contrib. Embryol. Carnegie Inst. 38: 59–70, 1966.

    Google Scholar 

  • Ramsey, E.M., Corner, G.W., Jr., and Donner, M.W.: Serial and cineradioangiographic visualization of maternal circulation in the primate (hemochorial) placenta. Am. J. Obstet. Gynecol. 86: 213–225, 1963.

    PubMed  CAS  Google Scholar 

  • Ramsey, E.M., Martin, C.B., Jr., McGaughey, H.S., Jr., Kaiser, I.H., and Donner, M.W.: Venous drainage of the placenta in rhesus monkeys: radiographic studies. Am. J. Obstet. Gynecol. 95: 948–955, 1966.

    PubMed  CAS  Google Scholar 

  • Reddy, G.S., Norman, A.W., Willis, D.M., Goltzman, D., Guyda, H., Solomon, S., Philips, D.R., Bishop, J.E., and Mayer, E.: Regulation of vitamin D metabolism in normal human pregnancy. J. Clin. Endocrinol. Metab. 56: 363–370, 1983.

    Article  PubMed  CAS  Google Scholar 

  • Redline, R.W., and Lu, C.Y.: Specific defects in the antilisterial immune response in discrete regions of the murine uterus and placenta account for susceptibility to infection. J. Immunol. 140: 3947–3955, 1988.

    PubMed  CAS  Google Scholar 

  • Ren, S.G., and Braunstein, G.D.: Decidua produces a protein that inhibits choriogonadotrophin release from human trophoblasts. J. Clin. Invest. 87: 326–330, 1991.

    Article  PubMed  CAS  Google Scholar 

  • Reshef, E., Lei, Z.M., Rao, C.V., Pridham, D.D., Chegini, N., and Luborsky, J.L.: The presence of gonadotropin receptors in nonpregnant human uterus, human placenta, fetal membranes, and decidua. J. Clin. Endocrinol. Metab. 70: 421–430, 1990.

    Article  PubMed  CAS  Google Scholar 

  • Reynolds, S.R.M.: Formation of fetal cotyledons in the hemochorial placenta: a theoretical consideration of the functional implication of such an arrangements. Am. J. Obstet. Gynecol. 94: 425–439, 1966.

    PubMed  CAS  Google Scholar 

  • Riley, S.C., Walton, J.C., Herlick, J.M., and Challis, J.R.: The localization and distribution of corticotropin-releasing hormone in the human placenta and fetal membranes throughout gestation. J. Clin. Endocrinol. Metab. 72: 1001–1007, 1991.

    Article  PubMed  CAS  Google Scholar 

  • Riddick, D.H., and Daly, D.C.: Decidual prolactin in human gestation. Semin. Perinatol. 6: L229–237, 1982.

    Google Scholar 

  • Riley, S.C., Dupont, E., Walton, J.C., Luuthe, V., Labrie, F., Pelletier, G., and Challis, J.R.G.: Immunohistochemical localization of 30-hydroxy-5-ene-steroid dehydrogenase deltas — delta4 isomerase in human placenta and fetal membranes throughout gestation. J. Clin. Endocrinol. Metab. 75: 956–961, 1992.

    Article  PubMed  CAS  Google Scholar 

  • Ritson, A., and Bulmer, J.N.: Isolation and functional studies of granulated lymphocytes in first trimester human decidua. Clin. Exp. Immunol. 77: 263–268, 1989.

    PubMed  CAS  Google Scholar 

  • Robb, J.A., Benirschke, K., and Barmeyer, R.: Intrauterine latent herpes simplex virus infection. I. Spontaneous abortion. Hum. Pathol. 17: 1196–1209, 1986a.

    Article  PubMed  CAS  Google Scholar 

  • Robb, J.A., Benirschke, K., Mannino, F., and Voland, J.: Intrauterine latent herpes simplex virus infection. II. Latent neonatal infection. Hum. Pathol. 17: 1210–1217, 1986b.

    Article  PubMed  CAS  Google Scholar 

  • Robertson, W.B.: Uteroplacental vasculature. J. Clin. Pathol. 29(Suppl.):9–17, 1976; R. Coll. Pathol. 10: 9–17, 1976.

    CAS  Google Scholar 

  • Robertson, W.B., and Manning, P.J.: Elastic tissue in uterine blood vessels. J. Pathol. 112: 237–243, 1974.

    Article  PubMed  CAS  Google Scholar 

  • Robertson, W.B., and Warner, B.: The ultrastructure of the human placental bed. J. Pathol. 112: 203–211, 1974.

    Article  PubMed  CAS  Google Scholar 

  • Robinson, L., Grau, P., and Crandall, B.F.: Pregnancy outcomes after increasing maternal serum alpha-fetoprotein levels. Obstet. Gynecol. 74: 17–20, 1989.

    PubMed  CAS  Google Scholar 

  • Rohr, K.: Die Beziehungen der mütterlichen Gefäße zu den intervillösen Räumen der reifen Plazenta speziell zur Thrombose derselben (“weisser Infarkt”). Virchows Arch. [Pathol. Anat.] 115: 505–534, 1889.

    Google Scholar 

  • Romano, W.M., Lukash, L.A., Challis, J.R.G., and Mitchell, B.F.: Substrate utilization for estrogen synthesis by human fetal membranes and decidua. Am. J. Obstet. Gynecol. 155: 1170–1175, 1986.

    PubMed  CAS  Google Scholar 

  • Rosen, J.F., Roginsky, M., Nathenson, G., and Finberg, L.: 25-Hydroxyvitamin D: plasma levels in mothers and their premature infants with neonatal hypocalcemia. Am. J. Dis. Child. 127: 220–223, 1974.

    PubMed  CAS  Google Scholar 

  • Rosenberg, S.M., and Bhatnagar, A.S.: Sex steroid and human chorionic gonadotropin modulation of in vitro prolactin production by human term decidua. Am. J. Obstet. Gynecol. 148: 461–465, 1984.

    PubMed  CAS  Google Scholar 

  • Rosenberg, S.M., Maslar, I.A., and Riddick, D.H.: Decidual production of prolactin in late gestation: further evidence for a decidual source of amniotic fluid prolactin. Am. J. Obstet. Gynecol. 138: 681–685, 1980.

    PubMed  CAS  Google Scholar 

  • Rossant, J., and Croy, B.A.: Genetic identification of tissue of origin of cellular populations within the mouse placenta. J. Embryo]. Exp. Morphol. 86: 177–189, 1985.

    CAS  Google Scholar 

  • Ruffolo, R., Benirschke, K., Covington, H.I., and Munro, A.B.: Electron microscopic study of the “X-cells” in septal cysts of the human placenta. Am. J. Obstet. Gynecol. 99: 1147–1159, 1967.

    PubMed  CAS  Google Scholar 

  • Rukosuev, V.S., Nanaev, A.K., and Milovanov, A.P.: Participation of collagen types I, III, IV, V, and fibronectin in the formation of villi fibrosis in human term placenta. Acta Histochem. 89: 11–16, 1990.

    Article  PubMed  CAS  Google Scholar 

  • Ruoslahti, E., and Pierschbacher, M.D.: New perspectives in cell adhesion: RGD and integrins. Science 238: 491–497, 1987.

    Article  PubMed  CAS  Google Scholar 

  • Russell, J.G.B.: Antenatal diagnosis of placental calcification. J. Obstet. Gynaecol. Br. Commonw. 76: 813–126, 1969.

    Article  PubMed  CAS  Google Scholar 

  • Rutanen, E.M., Partanen, S., and Pekonen, F.: Decidual transformation of human extrauterine mesenchymal cells is associated with the appearance of insulin-like growth factor-binding protein-1. J. Clin. Endocrinol. Metab. 72: 27–31, 1991.

    Article  PubMed  CAS  Google Scholar 

  • Rutherford, R.N.: The significance of bleeding in early pregnancy as evidenced by decidual biopsy. Surg. Gynecol. Obstet. 74: 1139–1153, 1942.

    Google Scholar 

  • Sachs, H.: Quantitativ histochemische Untersuchung des Endometrium in der Schwangerschaft und der Placenta (Cytophotometrische Messungen). Arch. Gynecol. 205: 93104, 1968.

    Google Scholar 

  • Saijonmaa, O., Laatikainen, T., and Wahlström, T.: Corticotrophin-releasing factor in human placenta: localization, concentration and release in vitro. Placenta 9: 373–385, 1988.

    Article  PubMed  CAS  Google Scholar 

  • Saito, S., Nishikawa, K., Morii, T., Enomoto, M., Narita, N., Motoyoshi, K., and Ichijo, M.: Cytokine production by CD16–CD56(bright) natural killer cells in the human early pregnancy decidua. Int. Immunol. 5: 559–563, 1993.

    Article  PubMed  CAS  Google Scholar 

  • Saji, M., Taga, M., and Minaguchi, H.: Epidermal growth factor stimulate cell proliferation and inhibits prolactin secretion of the human decidual cells in culture. Endocrinol. Jpn. 37: 177–182, 1990.

    Article  PubMed  CAS  Google Scholar 

  • Sakbun, V., Ali, S.M., Greenwood, F.C., and Bryant Greenwood, G.D.: Human relaxin in the amnion, chorion, decidua parietalis, basal plate, and placental trophoblast by immunocytochemistry and Northern analysis. J. Clin. Endocrinol. Metab. 70: 508–514, 1990a.

    Article  PubMed  CAS  Google Scholar 

  • Sakbun, V., Ali, S.M., Lee, Y.A., Jara, C.S., and Bryant Greenwood, G.D.: Immunocytochemical localization and messenger ribonucleic acid concentrations for human placental lactogen in amnion, chorion, decidua, and placenta. Am. J. Obstet. Gynecol. 162: 1310–1317, 1990b.

    PubMed  CAS  Google Scholar 

  • Sala, M.A., Matheus, M., and Valeri, V.: Regional variation in the frequency of fibrinoid degeneration in the human term placenta. Z. Geburtshilfe Perinatol. 186: 80–81, 1982a.

    PubMed  CAS  Google Scholar 

  • Sala, M.A., Valeri, V., and Matheus, M.: Michaelis-Gutmann bodies in human placental fibrinoid. Arch. Biol. (Bruxelles) 93: 363–367, 19826.

    Google Scholar 

  • Sasagawa, M., Yamazaki, T., Sudo, Y., Kanazawa, K., and Takeuchi, S.: Immunohistochemical localization of hCG a, hCG ß, CTP, hPL and SP1 on villous and extravillous trophoblasts in normal human pregnancy. Nippon Sanka Fujinka Gakkai Zasshi 39: 1073–1079, 1987.

    PubMed  CAS  Google Scholar 

  • Sauramo, H.: Cytotrophoblast of the placenta and foetal membranes in normal and pathological obstetrics. Ann. Med. Exp. Fenn. 39: 7–12, 1961.

    PubMed  CAS  Google Scholar 

  • Schaaps, J.P., and Hustin, J.: In vivo aspect of the maternaltrophoblastic border during the first trimester of gestation. Trophoblast Res. 3: 39–48, 1988.

    Google Scholar 

  • Scheuner, G.: Über die Verankerung der Nabelschnur an der Plazenta. Morphol. Jahrb. 106: 73–89, 1964.

    Google Scholar 

  • Schiebler, T.H., and Kaufmann, P.: Reife Plazenta. In, Die Plazenta des Menschen. V. Becker, T.H. Schiebler, and F. Kubli, eds. Thieme, Stuttgart, 1981.

    Google Scholar 

  • Schiebler, T.H., and Knoop, A.: Histochemische und elektronenmikroskopische Untersuchungen an der Rattenplacenta. Z. Zellforsch. 50: 494–552, 1959.

    Article  PubMed  CAS  Google Scholar 

  • Schindler, A.M., Bordignon, P., and Bischof, P.: Immunohistochemical localization of pregnancy-associated plasma protein A in decidua and trophoblast: comparison with human chorionic gonadotrophin and fibrin. Placenta 5: 227–235, 1984.

    Article  PubMed  CAS  Google Scholar 

  • Schmidt-Matthiesen, H.: Das normale menschliche Endometrium. Thieme, Stuttgart, 1963.

    Google Scholar 

  • Schuhmann, R.: Plazenton: Begriff, Entstehung, funktionelle Anatomie. In, Die Plazenta des Menschen. V. Becker, T.H. Schiebler, and F. Kubli, eds., pp. 192–207. Thieme, Stuttgart, 1981.

    Google Scholar 

  • Schuhmann, R., and Wehler, V.: Histologische Unterschiede an Plazentazotten innerhalb der maternofetalen Strömungseinheit: ein Beitrag zur funktionellen Morphologie der Plazenta. Arch. Gynecol. 210: 425–439, 1971.

    CAS  Google Scholar 

  • Schultze, K.W.: Über Randsinusblutungen aus der Plazenta in der Schwangerschaft und unter der Geburt. Geburtshilfe Frauenheilkd. 13: 708–715, 1953.

    PubMed  CAS  Google Scholar 

  • Schultze, K.W.: Über sog. Plazenta-Randsinusblutungen. Dtsch. Hebammen. Z. 20: 1–4, 1968.

    Google Scholar 

  • Schwartz, A., Sauer, J., Hradeckky, L., and Pavlik, V.: Die Zysten der menschlichen Plazenta. Zentralbl. Allg. Pathol. 117: 185–190, 1973.

    PubMed  CAS  Google Scholar 

  • Scipiades, E., and Burg, E.: Über die Morphologie der menschlichen Placenta mit besonderer Rücksicht auf unsere eigenen Studien. Arch. Gynecol. 141: 577–619, 1930.

    Google Scholar 

  • Sengel, A., and Stöbner, P: Ultrastructure de l’endometre humain normal. III. Les cellules K. Z. Zellforsch. 133: 4757, 1972.

    Article  Google Scholar 

  • Sengupta, J., Given, R.L., Talwar, D., and Ghosh, D.: Endometrial response to deciduogenic stimulus in ovariectomized rhesus monkeys treated with oestrogen and progesterone: an ultrastructural study. J. Endocrinol. 124: 53–57, 1990.

    Article  PubMed  CAS  Google Scholar 

  • Serr, D.M., Sadowski, A.D., and Kohn, G.: The placental septa; a study based upon nuclear morphological sex difference. J. Obstet. Gynaecol. Br. Commonw. 65: 747–777, 1958.

    Article  Google Scholar 

  • Shanklin, D.R., and Scott, J.S.: Massive subchorial thrombohaematoma (Breus’ mole). Br. J. Obstet. Gynaecol. 82: 476–487, 1975.

    Article  PubMed  CAS  Google Scholar 

  • Sheppard, B.L., and Bonnar, J.: Scanning electron microscopy of the human placenta and decidual spiral arteries in normal pregnancy. J. Obstet. Gynaecol. Br. Commonw. 81: 17–20, 1974a.

    Google Scholar 

  • Sheppard, B.L., and Bonnar, J.: The ultrastructure of the arterial supply of the human placenta in early and late pregnancy. J. Obstet. Gynaecol. Br. Commonw. 81: 497511, 1974b.

    Google Scholar 

  • Sheppard, B.L., and Bonnar, J.: The ultrastructure of the arterial supply of the human placenta in pregnancy complicated by fetal growth retardation. Br. J. Obstet. Gynaecol. 83: 948–959, 1976.

    Article  PubMed  CAS  Google Scholar 

  • Sheppard, B.L., and Bonnar, J.: The maternal blood supply to the placenta in pregnancy complicated by intrauterine fetal growth retardation. Trophoblast Res. 3: 69–82, 1988.

    Google Scholar 

  • Shipley, C.F., and Nelson, G.H.: Prenatal diagnosis of a placental cyst: comparison of postnatal biochemical analyses of cyst fluid, amniotic fluid, cord serum, and maternal serum. Am. J. Obstet. Gynecol. 168: 211–213, 1993.

    PubMed  Google Scholar 

  • Shorter, S.C., Jackson, M.C., Sargent, I.L., Redman, C.W., and Starkey, P.M.: Purification of human cytotrophoblast from term amniochorion by flow cytometry. Placenta 11: 505–513, 1990.

    Article  PubMed  CAS  Google Scholar 

  • Shorter, S.C., Vince, G.S., and Starkey, P.M.: Production of granulocyte colony-stimulating factor at the maternofoetal interface in human pregnancy. Immunology 75: 468–474, 1992.

    PubMed  CAS  Google Scholar 

  • Shorter, S.C., Starkey, P.M., Ferry, B.L., Clover, L.M., Sargent, I.L., and Redman, C.W.G.: Antigenic heterogeneity of human cytotrophoblast and evidence for the transient expression of MHC class I antigens distinct from HLA-G. Placenta 14: 571–582, 1993.

    Article  PubMed  CAS  Google Scholar 

  • Simmen, R.C.M., Ko, Y., Liu, X.H., Wilde, M.H., Pope, W.F., and Simmen, F.A.: A uterine cell mitogen distinct from epidermal growth factor in porcine uterine luminal fluids: characterization and partial purification. Biol. Reprod. 38: 551–561, 1988.

    Article  PubMed  CAS  Google Scholar 

  • Singer, M., and Wislocki, G.B.: The affinity of syncytium, fibrin and fibrinoid of the human placenta for acid and basic dyes under controlled conditions of staining. Anat. Rec. 102: 175–194, 1948.

    Article  PubMed  CAS  Google Scholar 

  • Sinha, A.A.: Ultrastructure of human amnion and amniotic plaques of normal pregnancy. Z. Zellforsch. 122: 1–14, 1971.

    Article  PubMed  CAS  Google Scholar 

  • Sohval, A.R., Gaines, J.A., and Strauss, L.: Chromosomal sex determination in the human newborn and fetus from examination of the umbilical cord, placental tissue, and fetal membranes. Ann. N.Y. Acad. Sci. 75: 905–922, 1959.

    Article  PubMed  CAS  Google Scholar 

  • Soma, H., Satoh, M., Higashi, S., Horikiri, H., Hata, T., Isaka, K., and Malla, D.: Fine structure and biological properties of chorionic cysts. In: Placenta: Basic Research for Clinical Application. H. Soma, ed., pp. 200–208, Karger, Basel, 1991.

    Google Scholar 

  • Sonnenberg, A., Modderman, P.W., and Hogervorst, F.: Laminin receptor on platelets is the integrin VLA-6. Nature 336: 487–489, 1988.

    Article  PubMed  CAS  Google Scholar 

  • Sorensen, F.B., Marcussen, N., Daugaard, H.O., Kristiansen, J.D., Moller, J., and Ingerslev, H.J.: Immunohistological demonstration of intermediate trophoblast in the diagnosis of uterine versus ectopic pregnancy: a retrospective survey and results of a prospective trial. Br. J. Obstet. Gynaecol. 98: 463–469, 1991.

    Article  PubMed  CAS  Google Scholar 

  • Spanner, R.: Der Kreislauf im intervillösen Raum des Menschen: Untersuchungen an den Uteroplacentargefässen schwangerer Uteri. Anat. Anz. 78: 127–129, 1934.

    Google Scholar 

  • Spanner, R.: Mütterlicher und kindlicher Kreislauf der menschlichen Placenta und seine Strombahnen. Z. Ges. Anat. 105: 163–242, 1935.

    Article  Google Scholar 

  • Spanner, R.: Zellinseln und Zottenepithel in der zweiten Hälfte der Schwangerschaft. Morphol. Jahrb. 86: 407–461, 1941.

    Google Scholar 

  • Spornitz, U.M.: The functional morphology of the human endometrium and decidua. Adv. Anat. Embryol. Cell Biol. 124: 1–99, 1992.

    Article  PubMed  CAS  Google Scholar 

  • Spornitz, U.M., and Ludwig, K.S.: Die Ultrastruktur der menschlichen Deziduazelle. Acta Anat. (Basel) 120: 245, 1984.

    Google Scholar 

  • Stark, J., and Kaufmann, P.: Die Basalplatte der reifen menschlichen Placenta. II. Gefrierschnitt-Histochemie. Z. Anat. Entwicklungsgesch. 135: 185–201, 1971.

    Article  PubMed  CAS  Google Scholar 

  • Stark, J., and Kaufmann, P.: Die Basalplatte der reifen menschlichen Placenta. III. Bindegewebs-und Deciduazellen. Arch. Gynecol. 213: 399–417, 1973.

    CAS  Google Scholar 

  • Stark, J., and Kaufmann, P.: Infarktgenese in der Placenta. Arch. Gynecol. 217: 189–208, 1974.

    CAS  Google Scholar 

  • Stegner, H.E., Sachs, H., and Uthmöller, E.: Elektronenmikroskopische Untersuchungen am experimentellen Deziduom der Ratte. Z. Geburtshilfe Gynäkol. 174: 24 1251, 1971.

    Google Scholar 

  • Steininger, H.: Über die Herkunft von Septen und Inseln der menschlichen Plazenta. Arch. Gynecol. 226: 261–275, 1978.

    Article  PubMed  CAS  Google Scholar 

  • Stieve, H.: Neue Untersuchungen über die Placenta, besonders über die Entstehung der Placentasepten. Arch. Gynecol. 161: 160–167, 1936.

    Google Scholar 

  • Stieve, H.: Die Entwicklung und der Bau der menschlichen Placenta. I. Zotten, Trophoblastinseln und Scheidewaende in der ersten Hälfte der Schwangerschaft. Z. Mikrosk. Anat. Forsch. 48: 287–358, 1940.

    Google Scholar 

  • Stieve, H., and von der Heide, I.: Über die Entwicklung der Septen in der menschlichen Plazenta. Anat. Anz. 92: 1–16, 1941.

    Google Scholar 

  • Straatsburg, I.H., and Gossrau, R.: Enzyme histochemistry of the regressing rat decidua and metrial gland. Acta Histochem. 94: 202–219, 1993.

    Article  PubMed  CAS  Google Scholar 

  • Sunderland, C.A., Bulmer, J.N., Luscombe, M., Redman, C.W.G., and Stirrat, G.M.: Immunohistological and biochemical evidence for a role for hyaluronic acid in the growth and development of the placenta. J. Reprod. Immunol. 8: 197–212, 1985.

    Article  PubMed  CAS  Google Scholar 

  • Sutcliffe, R.G., Davies, M., Hunter, J.B., Waters, J.J., and Parry, J.E.: The protein composition of the fibrinoid material at the human uteroplacental interface. Placenta 3: 297–308, 1982.

    Article  PubMed  CAS  Google Scholar 

  • Sutherland, A.E., Calarco, P.G., and Damsky, C.H.: Expression and function of cell surface extracellular matrix receptors in mouse blastocyst attachment and outgrowth. J.Cell Biol. 106: 1331–1348, 1988.

    Article  PubMed  CAS  Google Scholar 

  • Swinburne, L.M.: Leucocyte antigens and placental sponge. Lancet 2: 592–593, 1970.

    Article  PubMed  CAS  Google Scholar 

  • Takayama, M., Isaka, K., Suzuki, Y., Funayama, H., Akiya, K., and Bohn, H.: Comparative study of placental protein 19, human chorionic gonadotrophin and pregnancy-specific 01-glycoprotein as immunohistochemical markers for extravillous trophoblast in pregnancy and trophoblastic disease. Histochemistry 93: 167–173, 1989.

    Article  PubMed  CAS  Google Scholar 

  • Tarachand, U.: Morphogenesis and postulated functions of decidual cells. Biol. Res. Pregnancy Perinatol. 6: 187–190, 1985.

    PubMed  CAS  Google Scholar 

  • Tarachand, U.: Decidualisation: origin and role of associated cells. Biol. Cell 57: 9–16, 1986.

    Article  PubMed  CAS  Google Scholar 

  • Tavare, J.M., and Holmes, C.H.: Differential expression of the receptors for epidermal growth factor and insulin in the developing human placenta. Cell Signal 1: 55–64, 1989.

    Article  PubMed  CAS  Google Scholar 

  • Tekelioglu-Uysal, M., Edwards, R.J., and Kisnisci, H.A.: Ultrastructural relationships between decidua, trophoblast and lymphocytes at the beginning of human pregnancy. J. Reprod. Fertil. 42: 431–438, 1975.

    Article  PubMed  CAS  Google Scholar 

  • Thiede, H.A., and Choate, J.W.: Chorionic localization in the human placenta by immunofluorescent staining. II. Demonstration of hCG in the trophoblast and amnion epithelium of immature and mature placentas. Obstet. Gynecol. 22: 433–443, 1963.

    PubMed  CAS  Google Scholar 

  • Thliveris, J.A., and Speroff, L.: Ultrastructure of the placental villi, chorion laeve, and decidua parietalis in normal and hypertensive pregnant women. Am. J. Obstet. Gynecol. 129: 492–498, 1977.

    PubMed  CAS  Google Scholar 

  • Thomas, J.B.: Breus’ mole. Obstet. Gynecol. 24: 794–797, 1964.

    PubMed  CAS  Google Scholar 

  • Thomsen, K., and Willemsen, R.: Histochemische Untersuchungen über die Produktionsorte der Choriongonadotropine. Acta Endocrinol. (Copenh.) 30: 161–174, 1959.

    CAS  Google Scholar 

  • Thrailkill, K.M., Golander, A., Underwood, L.E., Richards, R.G., and Handwerger, S.: Insulin stimulates the synthesis and release of prolactin from human decidual cells. Endocrinology 124: 3010–3014, 1989.

    Article  PubMed  CAS  Google Scholar 

  • Thrower, S., Bulmer, J.N., Griffin, N.R., and Wells, M.: Further studies of lectin binding by villous and extravillous trophoblast in normal and pathological pregnancy. Int. J. Gynecol. Pathol. 10: 238–251, 1991.

    Article  PubMed  CAS  Google Scholar 

  • Tighe, J.R., Garrod, P.R., and Curran, R.C.: The trophoblast of the human chorionic villus. J. Pathol. Bacteriol. 93: 559–567, 1967.

    Article  PubMed  CAS  Google Scholar 

  • Tindall, V.R., and Scott, J.S.: Placental calcification: a study of 3,025 singleton and multiple pregnancies. J. Obstet. Gynaecol. Br. Commonw. 72: 356–373, 1965.

    Article  PubMed  CAS  Google Scholar 

  • Torpin, R.: Subchorial haematoma mole: hypothetical aetiology. J. Obstet. Gynaecol. Br. Emp. 67: 990, 1960.

    Article  PubMed  CAS  Google Scholar 

  • Torpin, R.: Breus subchorial hematoma mole at three or four months of pregnancy. Pacific Med. Surg. 74: 226–227, 1966.

    Google Scholar 

  • Tsang, R.C., Donavan, E.F., and Steichen, J.J.: Calcium physiology and pathology in the neonate. Pediatr. Clin. North Am. 23: 611–626, 1976.

    PubMed  CAS  Google Scholar 

  • Tuttle, S.E., O’Toole, R.V., O’Shaughnessy, R.W., and Zuspan, F.P.: Immunohistochemical evaluation of human placental implantation: an initial study. Am. J. Obstet. Gynecol. 153: 239–244, 1985.

    PubMed  CAS  Google Scholar 

  • Uhlendorf, B., and Kaufmann, P.: Die Entwicklung des Plazentastieles beim Meerschweinchen. Zentralbl. Veterinarmed. [C] 8: 233–247, 1979.

    CAS  Google Scholar 

  • Vernof, K.K., Benirschke, K., Kephart, G.M., Wasmoen, T.L., and Gleich, G.J.: Maternal floor infarction: relationship to X cells, major basic protein, and adverse perinatal outcome. Am. J. Obstet. Gynecol. 167: 1355–1963, 1992.

    PubMed  CAS  Google Scholar 

  • Vicovac, L., Jones, C.J.P., and Aplin, J.D.: Morphogenesis of human placental anchoring villi in culture. Placenta 14: A. 80, 1993.

    Google Scholar 

  • Wachstein, M., Meagher, J.G., and Ortiz, J.: Enzymatic histochemistry of the term human placenta. Am. J. Obstet. Gynecol. 87: 13–26, 1963.

    PubMed  CAS  Google Scholar 

  • Wadsworth, P.F., Lewis, D.J., and Heywood, R.: The ultra-structural features of progestagen-induced decidual cells in the rhesus monkey (Macaca mulatta). Contraception 22: 189–198, 1980.

    Article  PubMed  CAS  Google Scholar 

  • Waidl, E.: Die Entstehung der Septen und Furchen der menschlichen Plazenta. Geburtshilfe Frauenheilkd. 23: 757–766, 1963.

    PubMed  CAS  Google Scholar 

  • Wakuda, K., and Yoshida, Y.: Cytofluorometric nuclear DNA analysis and immunohistochemical study on the proliferative activity of the trophoblasts in human early gestation. Nippon Sanka Fujinka Gakkai Zasshi 42: 1182–1188, 1990.

    PubMed  CAS  Google Scholar 

  • Wakuda, K., and Yoshida, Y.: DNA ploidy and proliferative characteristics of human trophoblasts. Acta Obstet. Gynecol. Scand. 71: 12–16, 1992.

    Article  CAS  Google Scholar 

  • Wang, D., Fujii, S., Konishi, I., Nanbu, Y., Iwai, T., Nonogaki, H., and Mori, T.: Expression of c-erbB-2 protein and epidermal growth factor receptor in normal tissues of the female genital tract and in the placenta. Virchows Arch. [A] 420: 385–393, 1992.

    Article  CAS  Google Scholar 

  • Wanner, A.: Wird bei der Geburtsplacenta des Menschen die Basalplatte von Trophoblastzellen oder Zellen mütterlicher Herkunft überzogen? Acta Anat. (Basel) 63: 545–558, 1966.

    CAS  Google Scholar 

  • Wasmoen, T.L., Loegering, D.A., Coulam, C.B., Gleich, G.J., and Benirschke, K.: Characterization of a pregnancy-associated protein immunochemically similar to the major basic protein of eosinophils. Fed. Proc. 44: 420, 1985.

    Google Scholar 

  • Wasmoen, T.L., Benirschke, K., and Gleich, G.J.: Demonstration of immunoreactive eosinophil granule major basic protein in the plasma and placentae of non-human primates. Placenta 8: 283–292, 1987a.

    Article  PubMed  CAS  Google Scholar 

  • Wasmoen, T.L., Coulam, C.B., Leiferman, K.M., and Gleich, G.J.: Increase of plasma eosinophil major basic protein levels late in pregnancy predicts onset of labor. Proc. Natl. Acad. Sci. U.S.A. 84: 3029–3032, 1987b.

    Article  PubMed  CAS  Google Scholar 

  • Wasmoen, T.L., Bell, M.P., Loegering, D.A., Gleich, G.J., Prendergast, F.G., and McKean, D.J.: Biochemical and amino acid sequence analysis of human eosinophil granule major basic protein. J. Biol. Chem. 263: 12559–12563, 1988.

    PubMed  CAS  Google Scholar 

  • Wasmoen, T.I., McKean, D.J., Benirschke, K., Coulam, C.B., and Gleich, G.J: Evidence of eosinophil granule major basic protein in human placenta. J. Exp. Med. 170: 2051 2063, 1989.

    Google Scholar 

  • Wasmoen, T.L., Coulam, C.B., Benirschke, K., and Gleich, G.J.: Association of immunoreactive eosinophil major basic protein with placental septa and cysts. Am. J. Obstet. Gynecol. 165: 416–420, 1991.

    PubMed  CAS  Google Scholar 

  • Watanabe, S.: Studies of endometrial granulocytes in early pregnant decidual tissue by means of double immunofluorescent staining and flow cytometry. Nippon Sanka Fujinka Gakkai Zasshi 39: 972–979, 1987.

    PubMed  CAS  Google Scholar 

  • Weber, J.: The site of production of gonadotrophin in the placenta at term. Acta Obstet. Gynecol. Scand. 40: 139151, 1961.

    Google Scholar 

  • Weller, P.F., and Götzl, E.J.: The human eosinophil: roles in host defense and tissue injury. Am. J. Pathol. 100: 793–820, 1980.

    Google Scholar 

  • Wells, M., Hsi, B.-L., Yeh, C.-J., and Faulk, W.P.: Spiral (uteroplacental) arteries of the human placental bed show the presence of amniotic basement membrane antigens. Am. J. Obstet. Gynecol. 150: 973–977, 1984.

    PubMed  CAS  Google Scholar 

  • Welsh, A.O., and Enders, A.C.: Light and electron microscopic examination of the mature decidual cells of the rat with emphasis on the antimesometrial decidua and its degeneration. Am. J. Anat. 172: 1–29, 1985.

    Article  PubMed  CAS  Google Scholar 

  • Welsh, A.O., and Enders, A.C.: Chorioallantoic placenta formation in the rat. III. Granulated cells invade the uterine luminal epithelium at the time of epithelial cell death. Biol. Reprod. 49: 38–57, 1993.

    Article  PubMed  CAS  Google Scholar 

  • Weser, H., and Kaufmann, P.: Lichtmikroskopische und histochemische Untersuchungen an der Chorionplatte der reifen menschlichen Placenta. Arch. Gynecol. 225: 15–30, 1978.

    CAS  Google Scholar 

  • Wewer, U.M., Faber, M., Liotta, L.A., and Albrechtsen, R.: Immunochemical and ultrastructural assessment of the nature of pericellular basement membrane of human decidual cells. Lab. Invest. 53: 624–633, 1985.

    PubMed  CAS  Google Scholar 

  • Wewer, U.M., Faber, M., Liotta, L.A., and Albrechtsen, R.: Correspondence: decidual cells. Lab. Invest. 55: 120–121, 1986.

    Google Scholar 

  • Wewer, U.M., Albrechtsen, R., Fisher, L.W., Young, M.F., and Termine, J.D.: Osteonectin/SPARC/BM-40 in human decidua and carcinoma, tissues characterized by de novo formation of basement membrane. Am. J. Pathol. 132: 345355, 1988.

    Google Scholar 

  • Wieloch, J.: Beitrag zur Kenntnis des Baues der Placenta. Arch. Gynäkol. 118: 112–119, 1923.

    Article  Google Scholar 

  • Wiese, K.-H.: Licht-und elektronenmikroskopische Untersuchungen an der Chorionplatte der reifen menschlichen Plazenta. Arch. Gynecol. 218: 243–259, 1975.

    CAS  Google Scholar 

  • Wigger, H.J.: Villous fibrinoid of the placenta: result of holocrine secretion of the cytotrophoblast. Am. J. Pathol. 86: 8a, 1977.

    Google Scholar 

  • Wigglesworth, J.S.: Morphological variations in the insufficient placenta. J. Obstet. Gynaecol. Br. Commonw. 71: 871–884, 1964.

    Article  PubMed  CAS  Google Scholar 

  • Wigglesworth, J.S.: Vascular anatomy of the human placenta and its significance for placental pathology. J. Obstet. Gynäkol. Br. Commonw. 76: 979–989, 1969.

    Article  CAS  Google Scholar 

  • Wilkin, P.: Morphogenese. In, Le Placenta Humain. J. Snoeck, ed., pp. 23–70. Masson, Paris, 1958.

    Google Scholar 

  • Winkler, F.N.: Zur Kenntnis der menschlichen Plazenta. Arch. Gynecol. 4: 238–265, 1872.

    Google Scholar 

  • Wislocki, G.B.: The histology and cytochemistry of the basal plate and septa placentae of the normal human placenta delivered at full term. Anat. Rec. 109: 359, 1951.

    Article  Google Scholar 

  • Wislocki, G.B., and Streeter, G.L.: On the placentation of the macaque (Macaca mulatta) from the time of implantation until the formation of the definitive placenta. Contrib. Embryol. Carnegie Instit. 27: 1–66, 1938.

    Google Scholar 

  • Witter, F.R., and Sanders, R.C.: Maternal hemorrhage into the amniotic sac producing an apparent umbilical cord mass on sonogram. Am. J. Obstet. Gynecol. 155: 649–651, 1986.

    PubMed  CAS  Google Scholar 

  • Wolf, H.K., and Michalopoulos, G.K.: Proliferating cell nuclear antigen in human placenta and trophoblastic disease. Pediatr. Pathol. 12: 147–154, 1992.

    Article  PubMed  CAS  Google Scholar 

  • Wolska, W.: Über die von Ruge beschriebene Vaskularisation der Serotina. Thesis, Bern, 1888.

    Google Scholar 

  • Wu, W.X., Brooks, J., Millar, M.R., Ledger, W.L., Saunders, P.T., Glasier, A.F., and McNeilly, A.S.: Localization of the sites of synthesis and action of prolactin by immunocytochemistry and in-situ hybridization within the human uteroplacental unit. J. Mol. Endocrinol. 7: 241–247, 1991.

    Article  PubMed  CAS  Google Scholar 

  • Wynn, R.M.: Electron microscopy of the developing decidua. Fertil. Steril. 16: 16–26, 1965.

    PubMed  CAS  Google Scholar 

  • Wynn, R.M.: Fetomaternal cellular relations in the human basal plate: an ultrastructural study of the placenta. Am. J. Obstet. Gynecol. 97: 832–850, 1967a.

    PubMed  CAS  Google Scholar 

  • Wynn, R.M.: Intra-uterine devices: effects on ultrastructure of human endometrium. Science 156: 1508–1510, 1967b.

    Article  PubMed  CAS  Google Scholar 

  • Wynn, R.: Ultrastructural development of the human decidua. Am. J. Obstet. Gynecol. 118: 652–670, 1974.

    PubMed  CAS  Google Scholar 

  • Wynn, R.M.: Fine structure of the placenta. In, The Placenta and its Maternal Supply Line. P. Gruenwald, ed., pp. 5679. Medical Technical Publications, Lancaster, 1975.

    Google Scholar 

  • Yeh, I., O’Connor, D.M., and Kurman, R.J.: Further immunocytochemical characterization of intermediate trophoblast. Mod. Pathol. 1: 106A, 1988.

    Google Scholar 

  • Yeh, I., O’Connor, D.M., and Kurman, R.J.: Vacuolated cytotrophoblast: a sub-population of trophoblast in the chorion laeve. Placenta 10: 429–438, 1989.

    Article  PubMed  CAS  Google Scholar 

  • Yeh, I.T., O’Connor, D.M., and Kurman, R.J.: Intermediate trophoblast: further immunocytochemical characterization. Mod. Pathol. 3: 282–287, 1990.

    PubMed  CAS  Google Scholar 

  • Young, R.H., Kurman, R.J., and Scully, R.E.: Proliferations and tumors of intermediate trophoblast of the placental site. Semin. Diagn. Pathol. 5: 223–237, 1988.

    PubMed  CAS  Google Scholar 

  • Yuen, B.H., Moon, Y.S., and Shin, D.H.: Inhibition of human chorionic gonadotropin production by prolactin from term human trophoblast. Am. J. Obstet. Gynecol. 154: 336–340, 1986.

    PubMed  CAS  Google Scholar 

  • Zeng, C.X., and Fu, X.S.: Immunocytochemical localization of human chorionic gonadotropin and placental lactogen in normal placentae. Chung Hua Fu Chan Ko Tsa Chih 26: 155–157, 188, 1991.

    Google Scholar 

  • Zhemkova, Z.P.: Sex chromatin in human placenta. Arkh. Anat. Histol. Embriol. 39: 24–32, 1960.

    CAS  Google Scholar 

  • Zhou, Y., Damsky, C.H., Chiu, K., Roberts, J.M., and Fisher, S.J.: Preeclampsia is associated with abnormal expression of adhesion molecules by invasive cytotrophoblasts. J. Clin. Invest. 91: 950–960, 1993.

    Article  PubMed  CAS  Google Scholar 

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© 1995 Springer Science+Business Media New York

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Benirschke, K., Kaufmann, P. (1995). Nonvillous Parts of the Placenta. In: Pathology of the Human Placenta. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-4196-4_11

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  • DOI: https://doi.org/10.1007/978-1-4757-4196-4_11

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