Age-Related Physiologic Changes in the Gastrointestinal Tract

  • Joshua L. Levine
  • Michael E. Zenilman


The multitude of changes that take place in the gastrointestinal tract throughout the life of a human have various clinical and surgical repercussions. Although our knowledge of age-related changes is growing, their consequences are still the subject of much debate and controversy. One problem when assessing the effects of aging on humans is the extreme physiologic variability seen among elderly individuals. As individuals age, differences among them increase, such as those relating to their genetic distinctions, exposure to toxins, and environmental, psychological, and physical factors. Additionally, it becomes increasingly difficult to isolate control groups of healthy subjects because the elderly commonly have multiple medical problems. Many of these illnesses, such as diabetes, tend to confound study outcomes by adversely affecting the organs studied. Another obstacle to studying age-related changes involves the vast reserve capacity with which the human body is endowed.


Beta Cell Proliferate Cell Nuclear Antigen Elderly Subject Malt Lymphoma Myenteric Plexus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer Science+Business Media New York 2001

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  • Joshua L. Levine
  • Michael E. Zenilman

There are no affiliations available

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