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Effects of Toxic Substances on the Heart

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Physiology and Pathophysiology of the Heart

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 34))

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Abstract

The reactions of the heart to toxic injury can be classified according to whether they represent: (a) a direct toxic effect of the agent, (b) the result of an exaggeration of the pharmacologic effects of the agent either on the myocardium itself or on the coronary or systemic circulation, or (c) an allergic or hypersensitivity phenomenon. These etiologic distinctions are not always clear on anatomic study of the heart lesions resulting from toxic injury, as a wide spectrum of complex cardiac morphologic changes has been associated with the effects of toxic drugs and chemicals on humans and on experimental animals.

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  1. Victor J. Ferrans
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Editors and Affiliations

  1. Department of Physiology, University of Cincinnati Medical Center, 231 Bethesda Avenue, 45267, Cincinnati, Ohio, USA

    Nicholas Sperelakis

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Ferrans, V.J. (1984). Effects of Toxic Substances on the Heart. In: Sperelakis, N. (eds) Physiology and Pathophysiology of the Heart. Developments in Cardiovascular Medicine, vol 34. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-1171-4_31

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  • DOI: https://doi.org/10.1007/978-1-4757-1171-4_31

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-1173-8

  • Online ISBN: 978-1-4757-1171-4

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