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Methods for the Isolation and Structural Characterization of Hepatocyte Gap Junctions

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Methods in Membrane Biology

Abstract

Electron microscopy has revealed several different kinds of morphologically distinguishable plasma membrane modifications which are involved in cell-cell interactions. In general, these specialized sites at the cell surface, collectively called intercellular junctions, may be divided into three broad functional categories: (1) those involved in intercellular adhesion, e.g., the desmosome, (2) those involved in regulating transepithelial permeability, e.g., the zonula occludens, and (3) those involved in intercellular communication, e.g., the chemical synapse and the gap junction.

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Authors and Affiliations

  1. Department of Anatomy, Harvard Medical School, Boston, Massachusetts, USA

    Daniel A. Goodenough

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  1. Daniel A. Goodenough
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Editor information

Editors and Affiliations

  1. Laboratory of Cell Biology, National Heart and Lung Institute, Bethesda, Maryland, USA

    Edward D. Korn

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© 1975 Plenum Press, New York

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Goodenough, D.A. (1975). Methods for the Isolation and Structural Characterization of Hepatocyte Gap Junctions. In: Korn, E.D. (eds) Methods in Membrane Biology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0265-1_2

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  • DOI: https://doi.org/10.1007/978-1-4757-0265-1_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-0267-5

  • Online ISBN: 978-1-4757-0265-1

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