Nuclear Terminal Deoxynucleotidyl Transferase (Tdt) in Leukemic Infiltrates of Testicular Tissue
Carefully monitored chemotherapy regimes and prophylactic control of meningeal disease1,2 have contributed to prolonged hematological remissions in childhood acute lymphoblastic leukemia (ALL). With this lengthened remission duration leukemic infiltration of the testis has become an increasingly recognised complication in boys especially after cessation of maintenance therapy3. Many centers have therefore instituted the policy of routine testicular biopsy before cessation of therapy in order to detect residual disease in this site4,5.
KeywordsAcute Lymphoblastic Leukemia Testicular Tissue Leukemic Blast Testicular Biopsy Childhood Acute Lymphoblastic Leukemia
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