Replication Functions Encoded by the Plasmid pSClOl

  • G. Churchward
  • P. Linder
  • L. Caro
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 179)


We describe the mapping of several genetic loci involved in the replication of the pSClOl plasmid. These include the origin of replication and a short segment of DNA that encodes a pSClOl incompatibility function. This short segment lies within the origin region. Flanking the incompatibility segment are two loci, repA and repB, which are required for replication. The product of the repA locus is shown to be trans-acting.


Short Segment Origin Region repA Locus DnaA Protein Replication Function 
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Copyright information

© Springer Science+Business Media New York 1984

Authors and Affiliations

  • G. Churchward
    • 1
  • P. Linder
    • 1
  • L. Caro
    • 1
  1. 1.Département de Biologie MoléculaireUniversité de GenèveGenève 4Switzerland

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