Respiratory Chain Systems in Theory and Practice

  • Peter Mitchell

Abstract

The deliberate evolution of conceptual conjectures has often acted as a spur and a guide for the experimental exploration of reality. That is the underlying theme of this paper. David Keilin’s concept of the respiratory chain is an excellent example. For strategic reasons, I propose to confine my commentary mainly to the part of the mitochondrial respiratory chain from succinate to oxygen, where our present knowledge of stoichiometry and possible mechanism provides a comparatively well-defined basis for constructive discussion and for the planning of further experimental exploration.

Keywords

Polypeptide Cyanide NADH Succinate Quinone 

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Copyright information

© Plenum Press,New York 1987

Authors and Affiliations

  • Peter Mitchell
    • 1
  1. 1.Glynn Research InstituteBodminUK

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