Alcoholism pp 161-166 | Cite as

Genetic Linkage Analysis: Simple Solutions for Complex Traits?

  • Luis A. Giuffra
Part of the NATO ASI Series book series (NSSA, volume 206)


Many human disorders are either partially or wholly determined by genetic factors. The identification of these genetic defects at the DNA level is a major goal with important implications. Such identification could greatly increase our understanding of diseases whose pathophysiology and clinical course are currently unknown. In turn, this could lead to logical improvements in the way the disorder is treated. Furthermore, antenatal diagnosis and the identification of carriers could provide the opportunity for more accurate genetic counseling.


Linkage Analysis Complex Trait Tuberous Sclerosis Duchenne Muscular Dystrophy Familial Aggregation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Luis A. Giuffra
    • 1
  1. 1.Department of Human GeneticsYale School of MedicineNew HavenUSA

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