Abstract
Malnutrition in cystic fibrosis (CF) has been associated with poor dietary intake, maldigestion and malabsorption of food, and increased nutrient requirements secondary to chronic: infection1. Recent studies have suggested that nutritional status influenced the progression of disease and nutritional supplementation was frequently included in the comprehensive management of this desease. But, children with exocrine pancreatic insufficiency, as observed in CF, might have secondary deficiency of the essential micronutrients specially Selenium (Se) deficiency2,3.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Park R.W., Granr R.J.: Gastrointestinal manifestations of cystic fibrosis: A review. Gastroentero1pgy 81:1149–1161.(1981)
Dworkin B., Newman L.J., Berezin S., Rosenthal W.S., Schwarz S.H., Weiss L. Low blood selenium levels in patients with cystic -fibrosis compared to controls and healthy adults. J. P. E. N. 11:38–41 (1987).
Vancaillie Bertrand M., De Bieville F., Neisens H., Kerrebijn K., Fernandes J. and Degenhart H. Trace metals in cystic -fibrosis. Acta Pediatr. Scand. 71:203–207 (1982).
W.A.Gunzler, H.Kremers, and L. Flohe. An improved coupled test procedure for glutathione peroxidase in blood. Z. Klin. Chem. Klin. Bigchem. 12:444– 448 (1974).
S.B. Dousset, M. Trouilh, and M.J. Foglietti, Plasma malonaldehyde levels during myocardial infarction. Clin. Chim. Acta... 129:319–322(1983).
R.L.Heath, A.L.Tappel A new sensitive assay for the mea surement of hydroperoxydes. Anal. Bipchem. 76: 184–191 (1976).
R.J. Stead, A.N. Redington, L.J. Hinks, B.E. Clayton, M.E. Hodson, J.C. Batten.Selenium deficiency and possible increased risk of carcinoma in adults with cystic fibrosis. Lancet. 19:862–863 (1985).
J.Neve, R. van Geffel, M.Hanocq and L.Nolle. Plasma and erythrocyte Zinc, Copper and Selenium in cystic fibrosis. Acta Pediair.Scand.72:437–440(1983).
H.C.Heinrich, E.E.Gabbe, K.H.Bartels et al. Bioavaibi1ity of food iron(59Fe), vitamin B12(60Co), and protein bound selenomethionine (75Se) in pancreatic exocrine insufficiency due to cystic fibrosis. Klin. Wochensehr. 55:595–601 (1977).
R.Castillo, C.Landon, K.Eckhardt, V.Morris, O.Levander and N.Lewiston. Selenium and vitamin E status in cystic fibrosis. J.Pediatr. 99 : 583–585 (1981).
J.D.Llyd-Sti11, H.E.Ganther.Selenium and glutathione peroxidase levels in cystic fibrosis. Pediatrìc5 65:1010–12 (1980).
P.Foucaud, P.Therond, M.Marchand, F.Brion, J.F.Demelier, J.Navarro. Selenium et Vitamine E au cours de la muc¤viscidose. Arch.Fr.Pediatr. 45:383–386. ( 1988) .
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1990 Plenum Press, New York
About this chapter
Cite this chapter
Richard, M.J., Aguilaniu, B., Arnaud, J., Gout, J.P., Favier, A. (1990). Selenium and Oxidant Injury in Patients with Cystic Fibrosis. In: Emerit, I., Packer, L., Auclair, C. (eds) Antioxidants in Therapy and Preventive Medicine. Advances in Experimental Medicine and Biology, vol 264. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5730-8_27
Download citation
DOI: https://doi.org/10.1007/978-1-4684-5730-8_27
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-5732-2
Online ISBN: 978-1-4684-5730-8
eBook Packages: Springer Book Archive