Abstract
Neutron Capture Therapy (NCT) was suggested in theory as a treatment for malignant tumors some 50 years ago. Since then, considerable data have accumulated on the mechanisms of action and possible application of this technique. This paper outlines a protocol for a controlled study of the use of Boron Neutron Capture Therapy (BNCT) for the treatment of Glioblastoma Multiforme (GM). The protocol is one component of a comprehensive national BNCT research program at the Idaho National Engineering Laboratory (INEL) directed towards validating (or invalidating) NCT as a treatment for human malignancies.
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Kornbulith, P. L., et al., 1985, Neoplasms of the Central Nervous System, in Cancer: Principles and Practice of Oncology, DeVita, V. T., Hellman, S., Rosenberg, S. A., editors, 1985, Lippincott, Philadelphia.
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© 1989 Plenum Press, New York
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Dorn, R.V., Spickard, J.H., Griebenow, M.L. (1989). A Proposed Protocol for Clinical Trials of Boron Neutron Capture Therapy in Glioblastoma Multiforme. In: Fairchild, R.G., Bond, V.P., Woodhead, A.D., Vivirito, K. (eds) Clinical Aspects of Neutron Capture Therapy. Basic Life Sciences, vol 50. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5622-6_18
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DOI: https://doi.org/10.1007/978-1-4684-5622-6_18
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-5624-0
Online ISBN: 978-1-4684-5622-6
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